Infer Cell-Cell Communication from Spatial Transcriptomics R package blisa version 0.2.0 Identifies cell-cell communication hotspots in spatial transcriptomics data using bivariate Local Moran's I statistics on hexagonally binned cells. Provides functions for spatial weighting, ligand-receptor pair filtering, hotspot detection, and visualisation of sender-receiver cell-type interactions. Software Imports: sf, spdep, Matrix, SpatialExperiment, SummarizedExperiment, ComplexHeatmap, ggplot2, viridisLite, grid Suggests: knitr, rmarkdown Yunshun Chen <yuchen@wehi.edu.au> Comprehensive R Archive Network (CRAN) Yunshun Chen [aut, cre], Lei Qin [aut], Lizhong Chen [aut] GPL (>= 3) 2026-06-02 application/tgz https://CRAN.R-project.org/package=blisa doi:10.32614/CRAN.package.blisa