Package: twosigma
Type: Package
Title: DE Analysis for Single-Cell RNA-Sequencing Data
Version: 1.0.2
Date: 2021-12-10
Authors@R: c(person("Eric", "Van Buren", email = "edvanburen@gmail.com",
  role = c("aut", "cre")),person("Yun", "Li",role="aut"),person("Di", "Wu",role="aut"),person("Ming", "Hu",role="aut"))
Maintainer: Eric Van Buren <edvanburen@gmail.com>
Description: Implements the TWO-Component Single Cell Model-Based Association Method (TWO-SIGMA) for gene-level differential expression (DE) analysis and DE-based gene set testing of single-cell RNA-sequencing datasets. See Van Buren et al. (2020) <doi:10.1002/gepi.22361> and Van Buren et al. (2021) <doi:10.1101/2021.01.24.427979>.   
License: AGPL-3
Imports: multcomp (>= 1.4-13), glmmTMB, methods, pscl (>= 1.5.5),
        pbapply (>= 1.4.0), parallel (>= 3.6.3), doParallel (>= 1.0.15)
Encoding: UTF-8
LazyData: false
URL: https://github.com/edvanburen/twosigma
BugReports: https://github.com/edvanburen/twosigma/issues
RoxygenNote: 7.1.0
Suggests: testthat
NeedsCompilation: no
Packaged: 2021-12-10 21:30:03 UTC; edvanburen
Author: Eric Van Buren [aut, cre],
  Yun Li [aut],
  Di Wu [aut],
  Ming Hu [aut]
Repository: CRAN
Date/Publication: 2021-12-13 09:40:02 UTC
Built: R 4.6.0; ; 2026-04-25 14:06:27 UTC; unix
