R: DE Analysis for Single-Cell RNA-Sequencing Data

# DE Analysis for Single-Cell RNA-Sequencing Data

## Documentation for package ‘twosigma’ version 1.0.2

- DESCRIPTION file
- Package NEWS
- Package README

## Help Pages

adhoc.twosigma | adhoc.twosigma: Perform the ad hoc method described in TWO-SIGMA paper
lr.twosigma | Convenient wrapper function for performing joint likelihood ratio tests using the TWO-SIGMA model.
lr.twosigma_custom | Convenient wrapper function for performing joint likelihood ratio tests with the TWO-SIGMA model using custom user-specified formulas.
simulate_zero_inflated_nb_random_effect_data | Simulated zero-inflated negative binomial data with random effects
test.vc.twosigma | Convenient wrapper function for performing (joint) likelihood ratio tests of variance components using the TWO-SIGMA model.
twosigma | Fit the TWO-SIGMA Model.
twosigmag | Gene set testing for single-cell RNA-sequencing data adjusting for inter-gene correlation.
twosigma_custom | Fit the TWO-SIGMA model with custom user-specified model formulas.