R: Trigger Strategy in Clinical Trials

# Trigger Strategy in Clinical Trials

## Documentation for package ‘triggerstrategy’ version 1.2.0

- DESCRIPTION file

## Help Pages

alpha2boundary | Convert cumulative alpha levels to normal critical boundaries
boundary2alpha | Convert normal critical boundaries to cumulative alpha levels.
corrMatGenerator | Correlation matrix generator
gbounds | Critical boundary in group sequential trials
marginalPwR | Marginal Power Rate
psPwRbhmb | Powers of testing the primary and secondary hypotheses
psPwRtrigger | Powers of testing the primary and secondary hypotheses using trigger strategy
sBoundsPh2 | Critical boundaries for the secondary endpoint in the partially hierarchical group sequential design
sErrRphInt2 | Type I error rate of the overall null hypothesis using the partial hierarchical design
solveAlphaXsampleSize | Sample size calculation
solveAlphaXsampleSizeGA | Sample size calculation using Genetic Algorithms
sPwRholm | Power of testing the secondary hypothesis using Holm
sPwRholmye | Power of testing the secondary hypothesis using Holm-Ye
sPwRnaiveBonf | Power of testing the secondary hypothesis using Bonferroni
sPwRph2 | Power of testing the secondary hypothesis in partially hierarchical design
sPwRtrigger | Power of testing the secondary hypothesis using Trigger strategy