Type: Package
Package: simIDM
Title: Simulating Oncology Trials using an Illness-Death Model
Version: 0.1.0
Authors@R: c(
    person("Alexandra", "Erdmann", , "alexandra.erdmann@uni-ulm.de", role = c("aut", "cre")),
    person("Kaspar", "Rufibach", , "kaspar.rufibach@roche.com", role = "aut"),
    person("Holger", "Löwe", , "hbj.loewe@gmail.com", role = "aut"),
    person("Daniel", "Sabanés Bové", , "daniel.sabanes_bove@roche.com", role = "aut"),
    person("F. Hoffmann-La Roche AG", role = c("cph", "fnd")),
    person("University of Ulm", role = c("cph", "fnd"))
  )
Description: Based on the illness-death model a large number of clinical
    trials with oncology endpoints progression-free survival (PFS) and
    overall survival (OS) can be simulated, see Meller, Beyersmann and
    Rufibach (2019) <doi:10.1002/sim.8295>.  The simulation set-up allows
    for random and event-driven censoring, an arbitrary number of
    treatment arms, staggered study entry and drop-out.  Exponentially,
    Weibull and piecewise exponentially distributed survival times can be
    generated. The correlation between PFS and OS can be calculated.
License: Apache License 2.0
URL: https://github.com/insightsengineering/simIDM/
BugReports: https://github.com/insightsengineering/simIDM/issues
Depends: R (>= 3.6)
Imports: checkmate, furrr, future, mstate, parallelly, stats, survival
Suggests: coxphw, knitr, mvna, prodlim, rmarkdown, rpact, testthat (>=
        3.0.0)
VignetteBuilder: knitr
Config/testthat/edition: 3
Encoding: UTF-8
Language: en-US
RoxygenNote: 7.2.3
NeedsCompilation: no
Packaged: 2023-12-11 09:17:50 UTC; sabanesd
Author: Alexandra Erdmann [aut, cre],
  Kaspar Rufibach [aut],
  Holger Löwe [aut],
  Daniel Sabanés Bové [aut],
  F. Hoffmann-La Roche AG [cph, fnd],
  University of Ulm [cph, fnd]
Maintainer: Alexandra Erdmann <alexandra.erdmann@uni-ulm.de>
Repository: CRAN
Date/Publication: 2023-12-11 10:20:02 UTC
Built: R 4.6.0; ; 2026-04-26 04:52:46 UTC; unix
