Package: pocrm
Type: Package
Title: Dose Finding in Drug Combination Phase I Trials Using PO-CRM
Version: 0.13
Date: 2021-09-07
Author: Nolan A. Wages
Maintainer: "Brewer, Ben (arb5mt)" <arb5mt@virginia.edu>
Depends: dfcrm, nnet
Imports: stats
Description: Provides functions to implement and simulate the partial order continual reassessment method (PO-CRM) of Wages, Conaway and O'Quigley (2011) <doi:10.1177/1740774511408748> for use in Phase I trials of combinations of agents. Provides a function for generating a set of initial guesses (skeleton) for the toxicity probabilities at each combination that correspond to the set of possible orderings of the toxicity probabilities specified by the user.
License: GPL-2
NeedsCompilation: no
Packaged: 2021-09-08 14:25:52 UTC; arb5mt
Repository: CRAN
Date/Publication: 2021-09-08 16:00:06 UTC
Built: R 4.6.0; ; 2026-04-25 21:13:57 UTC; unix
