Package: nphPower
Title: Sample Size Calculation under Non-Proportional Hazards
Version: 1.1.0
Authors@R: 
    person(given = "Huan",
           family = "Cheng",
           role = c("aut", "cre"),
           email = "hcheng1118@hotmail.com",
           comment = c(ORCID = "0000-0002-2552-7656"))
Description: Performs combination tests and sample size calculation for 
   fixed design with survival endpoints using combination tests under either
   proportional hazards or non-proportional hazards. The combination tests 
   include maximum weighted log-rank test and projection test. The sample 
   size calculation procedure is very flexible, allowing for user-defined
   hazard ratio function and considering various trial conditions like 
   staggered entry, drop-out etc. The sample size calculation also applies to 
   various cure models such as proportional hazards cure model, cure model with
   (random) delayed treatments effects. Trial simulation function is also provided 
   to facilitate the empirical power calculation. The references for 
   projection test and maximum weighted logrank test include Brendel et al. (2014)
   <doi:10.1111/sjos.12059> and Cheng and He (2021) <arXiv:2110.03833>. The 
   references for sample size calculation under proportional hazard include
   Schoenfeld (1981) <doi:10.1093/biomet/68.1.316> and Freedman (1982) <doi:10.1002/sim.4780010204>.
   The references for calculation under non-proportional hazards include 
   Lakatos (1988) <doi:10.2307/2531910> and Cheng and He (2023) <doi:10.1002/bimj.202100403>.
License: GPL (>= 2)
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.3.1
Imports: survival, stats, mvtnorm, MASS, zoo
Suggests: rmarkdown, knitr
URL: https://github.com/hcheng99/nphPower
Depends: R (>= 2.10)
NeedsCompilation: no
Packaged: 2024-03-27 14:26:33 UTC; huan.cheng
Author: Huan Cheng [aut, cre] (<https://orcid.org/0000-0002-2552-7656>)
Maintainer: Huan Cheng <hcheng1118@hotmail.com>
Repository: CRAN
Date/Publication: 2024-03-28 08:20:02 UTC
Built: R 4.6.0; ; 2026-04-26 04:22:34 UTC; unix
