Package: nonmem2rx
Type: Package
Title: Converts 'NONMEM' Models to 'rxode2'
Version: 0.1.9
Maintainer: Matthew Fidler <matthew.fidler@gmail.com>
Authors@R: c(person("Matthew","Fidler", role = c("aut", "cre"), email = "matthew.fidler@gmail.com", comment=c(ORCID="0000-0001-8538-6691")),
    person("Philip", "Delff", email = "philip@delff.dk",role = c("ctb")),
    person("Gabriel", "Staples", role="ctb", comment="string insensitive compare"))
Description: 'NONMEM' has been a tool for running nonlinear mixed
    effects models since the 80s and is still used today (Bauer 2019
    <doi:10.1002/psp4.12404>). This tool allows you to convert
    'NONMEM' models to 'rxode2' (Wang, Hallow and James (2016)
    <doi:10.1002/psp4.12052>) and with simple models 'nlmixr2' syntax
    (Fidler et al (2019) <doi:10.1002/psp4.12445>). The 'nlmixr2'
    syntax requires the residual specification to be included and it
    is not always translated. If available, the 'rxode2' model will
    read in the 'NONMEM' data and compare the simulation for the
    population model ('PRED') individual model ('IPRED') and residual
    model ('IWRES') to immediately show how well the translation is
    performing. This saves the model development time for people who are
    creating an 'rxode2' model manually.  Additionally, this package reads
    in all the information to allow simulation with uncertainty (that is the
    number of observations, the number of subjects, and the covariance
    matrix) with a 'rxode2' model.  This is complementary to the
    'babelmixr2' package that translates 'nlmixr2' models to 'NONMEM' and can
    convert the objects converted from 'nonmem2rx' to a full 'nlmixr2' fit.
License: GPL (>= 3)
URL: https://nlmixr2.github.io/nonmem2rx/,
        https://github.com/nlmixr2/nonmem2rx/
Encoding: UTF-8
LinkingTo: dparser, Rcpp, rxode2
Imports: checkmate, digest, dparser, lotri, Rcpp, rxode2 (> 2.0.13),
        magrittr, cli, tools, utils, data.table, qs2, xml2, ggplot2,
        ggforce, crayon
Suggests: devtools, testthat (>= 3.0.0), nonmemica, NMdata, nonmem2R,
        withr, nlme, dplyr, xgxr, vdiffr, knitr, rmarkdown, spelling
Config/testthat/edition: 3
RoxygenNote: 7.3.3
VignetteBuilder: knitr
Language: en-US
NeedsCompilation: yes
Packaged: 2025-11-27 02:27:53 UTC; matt
Author: Matthew Fidler [aut, cre] (ORCID:
    <https://orcid.org/0000-0001-8538-6691>),
  Philip Delff [ctb],
  Gabriel Staples [ctb] (string insensitive compare)
Repository: CRAN
Date/Publication: 2025-11-27 06:10:18 UTC
Built: R 4.6.0; aarch64-apple-darwin23; 2026-04-25 13:55:59 UTC; unix
Archs: nonmem2rx.so.dSYM
