R: Understanding Nonlinear Mixed Effects Modeling for Population Pharmacokinetics

# Understanding Nonlinear Mixed Effects Modeling for Population Pharmacokinetics

## Documentation for package ‘nmw’ version 0.3.1

- DESCRIPTION file
- User guides, package vignettes and other documentation
- Package NEWS

## Help Pages

nmw-package | Understanding Nonlinear Mixed Effects Modeling for Population Pharmacokinetics
AddCox | Add a Covariate Column to an Existing NONMEM dataset
AddDoNoTaLD | Add Dose Number, Time of Latest Dose, and Time after Latest Dose
AddPage | Add a New Page to PDF
add_crcl_cg | Add CRCL Column via Cockcroft-Gault
BtwTagMat | Extract Matrix from NONMEM XML Output
BtwTagVals | Extract Vector of Values Between XML Tags
build_dose_records | Build NONMEM Dose Records
build_nm_dataset | Build a NONMEM-Format Dataset from DM/EX/PC
build_obs_records | Build NONMEM Observation Records
ClosePDF | Close PDF Output
code_race | Code RACE as Integer
code_sex | Code SEX as Integer
CombDmExPc | Combine the demographics(DM), dosing(EX), and DV(PC) tables into a new NONMEM dataset
CovStep | Covariance Step
crcl_cg | Cockcroft-Gault Creatinine Clearance
dat2_time_to_posix | Combine Date and Time Strings into POSIXct
DxPlotPost | Diagnostic Plot for Post-Processing
EBEpair | EBE Pair Plot
EstStep | Estimation Step
ExpandDoseHist | Expand Dose History with ADDL/II Records
GetAICc | Get Corrected AIC (AICc)
GetCountEps | Get Count of Epsilons
GetCountEta | Get Count of Etas
GetCountObs | Get Count of Observations
GetCountPara | Get Count of Parameters
GetEstMethod | Get Estimation Method
GetOFV | Get Objective Function Value
InitStep | Initialization Step
locf_value | LOCF / LOCB Lookup
LogDV | Check if Model Uses Log-Transformed DV (from Control File)
LogDV2 | Check if Model Uses Log-Transformed DV (from FSUBS)
merge_cov_locf | Merge Time-Varying Covariates by LOCF
MinSuccess | Check Minimization Success
mlr2 | Multiple Linear Regression with Influence Diagnostics
NMIDStat | NONMEM Individual (ID) Statistics
NMVarStat | NONMEM Variable Statistics
nmw | Understanding Nonlinear Mixed Effects Modeling for Population Pharmacokinetics
nmw_report_ebe | Generate EBE Diagnostics Report (S5-EBE.PDF)
nmw_report_indipk | Generate Individual PK Parameter Report (SC-IndiPK.PDF)
nmw_report_input | Generate Input Data Summary Report (SA-Input.PDF)
nmw_report_ofv | Generate OFV Diagnostic Report (S1-OFV.PDF)
nmw_report_output | Generate NONMEM Output Report (SB-Output.PDF)
nmw_report_param | Generate Parameter Estimates Report (S2-Parameters.PDF)
nmw_report_pred | Generate Prediction Diagnostics Report (S3-Predictions.PDF)
nmw_report_resid | Generate Residual Diagnostics Report (S4-Residuals.PDF)
nmw_run | Run All NONMEM Post-Processing Reports
nm_to_molar | Convert NM Dataset from Mass to Molar Units
Outline | Draw Model Development Flow Diagram
ParseOut | Parse Value After Tag from NONMEM Output
parse_dtc | Parse SDTM-Style DTC Strings into POSIXct
PrepPDF | Prepare PDF Output
PrinMTxt | Print Multiple Lines of Text
PrinTxt | Print Text at Position
RemoveNA | Remove Rows with NA Values
ResTest | Residual Count Test Using Binomial Distribution
run.test.nm | Runs Test for NONMEM Residuals
SESuccess | Check Standard Error Success
SumOut | Summarize Multiple NONMEM Runs
TabStep | Table Step
TrimOut | Trimming and beautifying NONMEM original OUTPUT file