Package: msce
Type: Package
Title: Hazard of Multi-Stage Clonal Expansion Models
Version: 1.0.2
Date: 2025-12-05
Authors@R: c(person(given = "Cristoforo",
                    family = "Simonetto",
                    role = c("aut", "cre"),
                    email = "cristoforo.simonetto@ph.tum.de",
                    comment = c(ORCID = "0000-0003-4816-3514")),
             person(given = c("Jan", "Christian"),
                    family = "Kaiser",
                    role = "ctb"))
Author: Cristoforo Simonetto [aut, cre] (ORCID:
    <https://orcid.org/0000-0003-4816-3514>),
  Jan Christian Kaiser [ctb]
Maintainer: Cristoforo Simonetto <cristoforo.simonetto@ph.tum.de>
Description: Functions to calculate hazard and survival function of Multi-Stage Clonal Expansion Models used in cancer epidemiology. For the Two-Stage Clonal Expansion Model an exact solution is implemented assuming piecewise constant parameters, see Heidenreich, Luebeck, Moolgavkar (1997) <doi:10.1111/j.1539-6924.1997.tb00878.x>. Numerical solutions are provided for its extensions, see also Little, Vineis, Li (2008) <doi:10.1016/j.jtbi.2008.05.027>.
License: GPL (>= 2)
Imports: Rcpp (>= 1.0.3), RcppParallel (>= 5.0.0)
LinkingTo: Rcpp, RcppParallel
Encoding: UTF-8
RoxygenNote: 7.3.3
Suggests: knitr, rmarkdown, testthat
VignetteBuilder: knitr
NeedsCompilation: yes
Packaged: 2025-12-16 23:37:14 UTC; cristoforo
Repository: CRAN
Date/Publication: 2025-12-17 00:00:02 UTC
Built: R 4.6.0; aarch64-apple-darwin23; 2026-04-25 20:35:42 UTC; unix
Archs: msce.so.dSYM
