Package: metasplines
Title: Pool Literature-Based and Individual Participant Data Based
        Spline Estimates
Version: 0.1.1
Authors@R: 
    person("Tommi", "Härkänen", , "tommi.harkanen@thl.fi", role = c("aut", "cre"))
Author: Tommi Härkänen [aut, cre]
Maintainer: Tommi Härkänen <tommi.harkanen@thl.fi>
Depends: R (>= 4.2.0)
Description: Pooling estimates reported in meta-analyses (literature-based, LB) and estimates based on individual participant data (IPD) is not straight-forward as the details of the LB nonlinear function estimate are not usually reported. This package pools the nonlinear IPD dose-response estimates based on a natural cubic spline from lm or glm with the pointwise LB estimates and their estimated variances. Details will be presented in Härkänen, Tapanainen, Sares-Jäske, Männistö, Kaartinen and Paalanen (2026) "Novel pooling method for nonlinear cohort analysis and meta-analysis estimates: Predicting health outcomes based on climate-friendly diets" Epidemiology <doi:10.1097/EDE.0000000000001932>.
License: GPL (>= 3)
Encoding: UTF-8
RoxygenNote: 7.3.3
Imports: rlang, dplyr, tidyr, tibble, stringr, meta, optimization
Suggests: knitr, rmarkdown, splines2
VignetteBuilder: knitr
NeedsCompilation: no
Packaged: 2026-01-12 12:56:30 UTC; thah
Repository: CRAN
Date/Publication: 2026-01-12 15:00:08 UTC
Built: R 4.6.0; ; 2026-04-26 19:40:32 UTC; unix
