>CLTR1_HUMAN
FRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYH---SAFQVYMINLAVADLLCVCTLPLR
VVYYV---WLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFPVQ---VTQKKAR
FVCVGIWIFVILTSSPFLMA---HVLVLHYVSLFVGFIIPFVIIIVCYTMIILTL---KK
NLSSHKKAIGMIMVVTAAFLVSFMPYHIQRTIHLHF---RMQKSVVITLSLAASNCCFDP
LLYFFSGGNFRKRL
>CLTR2_HUMAN
FKREFFPIVYLIIFFWGVLGNGLSIYVFLQPYK---TSVNVFMLNLAISDLLFISTLPFR
ADYYL---WIFGDLACRIMSYSLYVNMYSSIYFLTVLSVVRFLAMVHPFR---TSIRSAW
ILCGIIWILIMASSIMLLDS---KLQTMNYIALVVGCLLPFFTLSICYLLIIRVL---SG
LRVSHRKALTTIIITLIIFFLCFLPYHTLRTVHLTT---RLHKALVITLALAAANACFNP
LLYYFAGENFKDRL
>FFAR1_HUMAN
LPPQLSFGLYVAAFALGFPLNVLAIRGATAHAR---TPSLVYALNLGCSDLLLTVSLPLK
AVEAL---WPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLG---RRPCYSW
GVCAAIWALVLCHLGLVFGL---SAGPARFSLSLLLFFLPLAITAFCYVGCLRAL---GL
THRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLY---LGGSWRKLGLITGAWSVVLNP
LVTGYLGRGPGLKT
>FFAR2_HUMAN
WKSSLILMAYIIIFLTGLPANLLALRAFVGRIR---APVHILLLSLTLADLLLLLLLPFK
IIEAA---WYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQ---RRPLYGV
IAALVAWVMSFGHCTIVIIV---VVLPVRLELCLVLFFIPMAVTIFCYWRFVWIM---LV
GAQRRRRAVGLAVVTLLNFLVCFGPYNVSHLVGYHQ---KSPWWRSIAVVFSSLNASLDP
LLFYFSSSVVRRAF
>FFAR3_HUMAN
GNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLR---VAVDVLLLNLTASDLLLLLFLPFR
MVEAA---WPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLW---PRLGQAG
LVSVACWLLASAHCSVVYVI---ILLPVRLEMAVVLFVVPLIITSYCYSRLVWIL---GG
SHRRQRRVAGLVAATLLNFLVCFGPYNVSHVVGYIC---ESPVWRIYVTLLSTLNSCVDP
FVYYFSSSGFQADF
>GP132_HUMAN
ESRIVLVVVYSAVCTLGVPANCLTAWLALLQVL---NVLAVYLLCLALCELLYTGTLPLW
VIYIR---WTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALE---RRRRTAI
LISACIFILVGIVHYPVFQT---RIAGYYYARFTVGFAIPLSIIAFTNHRIFRSI---GL
SAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAA---RLYTASVVFLCLSTVNGVADP
IIYVLATDHSRQEV
>GP141_HUMAN
IVTPHLISLYFIVLIGGLVGVISILFLLVKMNT---SVTTMAVINLVVVHSVFLLTVPFR
LTYLI---WMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKD---YRKLHAV
AASAGMWTLVIVIVVPLVVS---YTYVKIINYMIVIFVIAVAVILLVFQVFIIML---SL
LSHQEFWAQLKNLFFIGVILVCFLPYQFFRIYYLNV---SKVAFYNEIFLSVTAISCYDL
LLFVFGGSHWFKQK
>GP171_HUMAN
KDLEPFTYFFYLVFLVGIIGSCFATWAFIQKNT---RCVSIYLINLLTADFLLTLALPVK
IVVDL---WKLKIFHCQVTACLIYINMYLSIIFLAFVSIDRCLQLTHSCK---QEPGFAK
MISTVVWLMVLLIMVPNMMI---NWHLLTNFICVAIFLNFSAIILISNCLVIRQL---NE
NYPNVKKALINILLVTTGYIICFVPYHIVRIPYTLS---SLFKAKEATLLLAVSNLCFDP
ILYYHLSKAFRSKV
>GP174_HUMAN
FRYFIYAVTYTVILVPGLIGNILALWVFYGYMK---KRAVIFMINLAIADLLQVLSLPLR
IFYYL---WPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFR---CKQKYDL
YISIAGWLIICLACVLFPLL---QSVVMMTIGELIGFVTPLLIVLYCTWKTVLSL---AQ
DLGEKQKALKMILTCAGVFLICFAPYHFSFPLDFLV---VILIFHSVALCLASLNSCLDP
VIYYFSTNEFRRRL
>GP183_HUMAN
TARIVMPLHYSLVFIIGLVGNLLALVVIVQNRK---NSTTLYSTNLVISDILFTTALPTR
IAYYA---WRIGDALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLR---KRIEHAK
GVCIFVWILVFAQTLPLLIN---SLPWILLGACFIGYVLPLIIILICYSQICCKL---TE
KSGVNKKALNTIILIIVVFVLCFTPYHVAIIQHMIK---SFQISLHFTVCLMNFNCCMDP
FIYFFACKGYKRKV
>GPR17_HUMAN
LENMLFASFYLLDFILALVGNTLALWLFIRDHK---TPANVFLMHLAVADLSCVLVLPTR
LVYHF---WPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVK---RRPLYAH
LACAFLWVVVAVAMAPLLVS---KASHHALVSLAVAFTFPFITTVTCYLLIIRSL---RV
EKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLH---ILALANRITSCLTSLNGALDP
IMYFFVAEKFRHAL
>GPR18_HUMAN
EYKIAALVFYSCIFIIGLFVNITALWVFSCTTK---TTVTIYMMNVALVDLIFIMTLPFR
MFYYA---WPFGEYFCQIIGALTVFYPSIALWLLAFISADRYMAIVQPKY---KNTCKAV
LACVGVWIMTLTTTTPLLLL---AVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNL---KL
KPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLG---SYNPWGAFTTFLMNLSTCLDV
ILYYIVSKQFQARV
>GPR20_HUMAN
GLCVALMAVHGAIFLAGLVLNGLALYVFCCRTR---TPSVIYTINLVVTDLLVGLSLPTR
FAVYY---ARGCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEA---RQPACAR
AVCAFVWLAAGAVTLSVLGV----PCCRVFALTVLEFLLPLLVISVFTGRIMCAL---HQ
GRQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVALW---TSLVVYHVAVTLSSLNSCMDP
IVYCFVTSGFQATV
>GPR31_HUMAN
VVATAVGVLLGLECGLGLLGNAVALWTFLFRVR---KPYAVYLLNLALADLLLAACLPFL
AAFYL---WHLGRVGCWALRFLLDLSRSVGMAFLAAVALDRYLRVVHPRL---LSPQAAL
GVSGLVWLLMVALTCPGLLI---FSIIWQEALSCLQFVLPFGLIVFCNAGIIRAL---PE
KQPKLQRAQALVTLVVVLFALCFLPCFLARVLMHIF---AVAHTSDVTGSLTYLHSVVNP
VVYCFSSPTFRSSY
>GPR34_HUMAN
LLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHR---NSIQIYLLNVAIADLLLIFCLPFR
IMYHI---WTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQ---ITTKQSI
YVCCIVWMLALGGFLTMIIL---KGEAIFNFILVVMFWLIFLLIILSYIKIGKNL---FP
NSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISS---IVHKTNEIMLVLSSFNSCLDP
VMYFLMSSNIRKIM
>GPR35_HUMAN
AIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQ---TETRIYMTNLAVADLCLLCTLPFV
LHSLR---DTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLR---RSPRQAA
AVCAVLWVLVIGSLVARWLL---RHNFNSMAFPLLGFYLPLAVVVFCSLKVVTAL---VG
QAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAV---TIRRALYITSKLSDANCCLDA
ICYYYMAKEFQEAS
>GPR4_HUMAN
VDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQ---NELGVYLMNLSIADLLYICTLPLW
VDYFL---WIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLR---RRVKTAV
AVSSVVWATELGANSAPLFH---WVAWMNLYRVFVGFLFPWALMLLSYRGILRAV---ST
ERQEKAKIKRLALSLIAIVLVCFAPYHVLLLSRSAI---RVFSAYHSSLAFTSLNCVADP
ILYCLVNEGARSDV
>GPR55_HUMAN
LMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLK---AATSIYMINLAVFDLLLVLSLPFK
MVLSQ---QSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLL---GPPGRSL
GSACTIWVLVWTGSIPIYSF---WSAKVFFPLEVFGFLLPMGIMGFCCSRSIHIL---TQ
DWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLV---SISFFLQLSMCFSNVNCCLDV
FCYYFVIKEFRMNI
>GPR81_HUMAN
TISQVMPPLLIVAFVLGALGNGVALCGFCFHMK---KPSTVYLFNLAVADFLLMICLPFR
TDYYL---WAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHH---ISTRVAA
GIVCTLWALVILGTVYLLLE---SANGWHDIMFQLEFFMPLGIILFCSFKIVWSL---LA
RQARMKKATRFIMVVAIVFITCYLPSVSARLYFLWT---SVHGALHITLSFTYMNSMLDP
LVYYFSSPSFPKFY
>GPR82_HUMAN
ISSMALPIIYILLCIVGVFGNTLSQWIFLTKIG---TSTHIYLSHLVTANLLVCSAMPFM
SIYFL---SAQCRVVNFLGTLSMHASMFVSLLILSWIAISRYATLMQKDS---RQPNFAR
KLCIYIWGVVLGIIIPVTVY---ISQIAGLIGTTFIGFSFLVVLTSYYSFVSHLR---ME
KDLTYSSVKRHLLVIQILLIVCFLPYSIFKPIFYVL---YLIETKNILTCLASARSSTDP
IIFLLLDKTFKKTL
>GPR87_HUMAN
FDTIVLPVLYLIIFVASILLNGLAVWIFFHIRN---TSFIFYLKNIVVADLIMTLTFPFR
IVHDA---WYFKFILCRYTSVLFYANMYTSIVFLGLISIDRYLKVVKPFG---YSITFTK
VLSVCVWVIMAVLSLPNIIL---KWHTAVTYVNSCLFVAVLVILIGCYIAISRYI---IS
QSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFS---ILYYCKEITLFLSACNVCLDP
IIYFFMCRSFSRRL
>LPAR4_HUMAN
FKYNLNGAVYSVVFILGLITNSVSLFVFCFRMK---SETAIFITNLAVSDLLFVCTLPFK
IFYNF---WPFGDTLCKISGTAFLTNIYGSMLFLTCISVDRFLAIVYPFR---RTRRNSA
IVCAGVWILVLSGGISASLF---YLSKITIFIEVVGFIIPLILNVSCSSVVLRTL---SQ
IGTNKKKVLKMITVHMAVFVVCFVPYNSVLFLYALV---FAKIMYPITLCLATLNCCFDP
FIYYFTLESFQKSF
>LPAR5_HUMAN
PTHRLHLVVYSLVLAAGLPLNALALWVFLRALR---SVVSVYMCNLAASDLLFTLSLPVR
LSYYA---WPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLR---RRPRVAR
LLCLGVWALILVFAVPAARV---RLLPLVLLAEALGFLLPLAAVVYSSGRVFWTL---AT
QSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLL---RVRGVLMVMVLLAGANCVLDP
LVYYFSAEGFRNTL
>NIAR1_HUMAN
FIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLK---KSSRIFLFNLAVADFLLIICLPFL
MDNYV---WKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHH---ISNRTAA
IISCLLWGITIGLTVHLLKK---HTFQWHEAMFLLEFFLPLGIILFCSARIIWSL---MD
RHAKIKRAITFIMVVAIVFVICFLPSVVVRIRIFWL---SVDLAFFITLSFTYMNSMLDP
VVYYFSSPSFPNFF
>OGR1_HUMAN
IHQTLAPVVYVTVLVVGFPANCLSLYFGYLQIK---NELGVYLCNLTVADLFYICSLPFW
LQYVL---WSHGDLSCQVCGILLYENIYISVGFLCCISVDRYLAVAHPFR---RTLKAAV
GVSVVIWAKELLTSIYFLMH---WQRAINYYRFLVGFLFPICLLLASYQGILRAV---GT
QKSRKDQIQRLVLSTVVIFLACFLPYHVLLLVRSVW---GVFNAYHFSLLLTSFNCVADP
VLYCFVSETTHRDL
>OXER1_HUMAN
LVSAFLAPILALEFVLGLVGNSLALFIFCIHTR---TSNTVFLVSLVAADFLLISNLPLR
VDYYL---WRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHH---ASVGAAA
RVAGGLWVGILLLNGHLLLS---ASLRWHQALYLLEFFLPLALILFAIVSIGLTI---LG
GQAGPQRAMRVLAMVVAVYTICFLPSIIFGMASMVA---LCTQLFHGSLAFTYLNSVLDP
VLYCFSSPNFLHQS
>OXGR1_HUMAN
LKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMR---KSSTIIMLNLACTDLLYLTSLPFL
IHYYA---WIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMS---HKTRCAV
VACAVVWIISLVAVIPMTFL---TIKWYNLILTATTFCLPLVIVTLCYTTIIHTL---QT
DSCLKQKARRLTILLLLAFYVCFLPFHILRVIRIES---QIHEAYIVSRPLAALNTFGNL
LLYVVVSDNFQQAV
>P2RY1_HUMAN
FQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMK---SGISVYMFNLALADFLYVLTLPAL
IFYYF---WIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLK---LKKKNAI
CISVLVWLIVVVAISPILFY---SYFIYSMCTTVAMFCVPLVLILGCYGLIVRAL---LD
NSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRA---RVYATYQVTRGLASLNSCVDP
ILYFLAGDTFRRRL
>P2RY2_HUMAN
FKYVLLPVSYGVVCVLGLCLNAVALYIFLCRLK---NASTTYMFHLAVSDALYAASLPLL
VYYYA---WPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLR---GRARYAR
RVAGAVWVLVLACQAPVLYF---RFVAYSSVMLGLLFAVPFAVILVCYVLMARRL---GG
LPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSF---AINMAYKVTRPLASANSCLDP
VLYFLAGQRLVRFA
>P2RY4_HUMAN
FKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLR---DATATYMFHLALSDTLYVLSLPTL
IYYYA---WPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLR---GRPRLAG
LLCLAVWLVVAGCLVPNLFF---HYVHFSSAVMGLLFGVPCLVTLVCYGLMARRL---SA
QSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLA---IVNVVYKVTRPLASANSCLDP
VLYLLTGDKYRRQL
>P2RY5_HUMAN
FKYTLYGCMFSMVFVLGLISNCVAIYIFICVLK---NETTTYMINLAMSDLLFVFTLPFR
IFYFT---WPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFK---RTKRNAK
IVCTGVWLTVIGGSAPAVFV---YLSRIVIFIEIVGFFIPLILNVTCSSMVLKTL---SR
SKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLV---AVRTMYPITLCIAVSNCCFDP
IVYYFTSDTIQNSI
>P2RY6_HUMAN
FKQLLLPPVYSAVLAAGLPLNICVITQICTSRR---TRTAVYTLNLALADLLYACSLPLL
IYNYA---WPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLA---GGRRAAW
LVCVAVWLAVTTQCLPTAIF---HYMPYGMALTVIGFLLPFAALLACYCLLACRL---PV
AQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAV---AFAAAYKGTRPFASANSVLDP
ILFYFTQKKFRRRP
>P2RY8_HUMAN
AIAVALPVVYSLVAAVSIPGNLFSLWVLCRRMG---SPSVIFMINLSVTDLMLASVLPFQ
IYYHC---WVFGVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLS---RRRRYAV
AACAGTWLLLLTALSPLART---MWAVFLFTIFILLFLIPFVITVACYTATILKL---AH
GREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVS---SYYHVYKLTLCLSCLNNCLDP
FVYYFASREFQLRL
>P2Y10_HUMAN
FQYSLYATTYILIFIPGLLANSAALWVLCRFIS---NKAIIFMINLSVADLAHVLSLPLR
IYYYI---WPFQRALCLLCFYLKYLNMYASICFLTCISLQRCFFLLKPFR---WKRRYDV
GISAAIWIVVGTACLPFPIL---ALVGMITVAELAGFVIPVIIIAWCTWKTTISL---FQ
GISERQKALRMVFMCAAVFFICFTPYHINFIFYTMV---IALYFHPFCLCLASLCCLLDP
ILYYFMASEFRDQL
>P2Y11_HUMAN
FQGDFLWPILVVEFLVAVASNGLALYRFSIRKQ---HPAVVFSVQLAVSDLLCALTLPPL
AAYLY---WRYGEAACRLERFLFTCNLLGSVIFITCISLNRYLGIVHPFF---LRPKHAW
AVSAAGWVLAALLAMPTLSF---AYRAYSLVLAGLGCGLPLLLTLAAYGALGRAV---GM
TVAEKLRVAALVASGVALYASSYVPYHIMRVLNVDA---GPYVGYQVMRGLMPLAFCVHP
LLYMAAVPSLGCCC
>P2Y12_HUMAN
ITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRS---SNFIIFLKNTVISDLLMILTFPFK
ILSDA---GPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFK---KNLLGAK
ILSVVIWAFMFLLSLPNMIL---VWHEIVNYICQVIFWINFLIVIVCYTLITKEL---GV
GKVPRKKVNVKVFIIIAVFFICFVPFHFARIPYTLS---TLFYVKESTLWLTSLNACLDP
FIYFFLCKSFRNSL
>P2Y13_HUMAN
IVQLVFPALYTVVFLTGILLNTLALWVFVHIPS---STFIIYLKNTLVADLIMTLMLPFK
ILSDS---WQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLR---KKPVFAK
TVSIFIWFFLFFISLPNMIL---KWHQMVNNICQFIFWTVFILMLVFYVVIAKKV---SK
DRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHS---QLFIAKETTLFLAATNICMDP
LIYIFLCKKFTEKL
>P2Y14_HUMAN
ITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPS---KSFIIYLKNIVIADFVMSLTFPFK
ILGDS---WQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLW---QSVSYSK
LLSVIVWMLMLLLAVPNIIL---KWHKASNYIFVAIFWIVFLLLIVFYTAITKKI---RN
STSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKS---ILRYMKEFTLLLSAANVCLDP
IIYFFLCQPFREIL
>PAR1_HUMAN
WLTLFVPSVYTGVFVVSLPLNIMAIVVFILKMK---KPAVVYMLHLATADVLFVSVLPFK
ISYYF---WQFGSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQ---RTLGRAS
FTCLAIWALAIAGVVPLLLK---YYAYYFSAFSAVFFFVPLIISTVCYVSIIRCL---VA
NRSKKSRALFLSAAVFCIFIICFGPTNVLLIAHYSF---AAYFAYLLCVCVSSISCCIDP
LIYYYASSECQRYV
>PAR2_HUMAN
LTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTK---HPAVIYMANLALADLLSVIWFPLK
IAYHI---WIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMG---KKANIAI
GISLAIWLLILLVTIPLYVV---DMFNYFLSLAIGVFLFPAFLTASAYVLMIRML---EN
SEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFL---HVYALYIVALCLSTLNSCIDP
FVYYFVSHDFRDHA
>PAR3_HUMAN
LSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTR---ICTTVFYTNLAIADFLFCVTLPFK
IAYHL---WVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFT---PKHTYAL
VTCGLVWATVFLYMLPFFIL---FQLYYFISLAFFGFLIPFVLIIYCYAAIIRTL---NA
YDHRWLWYVKASLLILVIFTICFAPSNIILIIHHAN---GLYFIYLIALCLGSLNSCLDP
FLYFLMSKTRNHST
>PAR4_HUMAN
VPTRLVPALYGLVLVVGLPANGLALWVLATQAP---LPSTMLLMNLATADLLLALALPPR
IAYHL---WPFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVHPLR---RGRRLAL
GLCMAAWLMAAALALPLTLQ---HWQPAFTCLALLGCFLPLLAMLLCYGATLHTL---AA
SGRRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSD---NLYGAYVPSLALSTLNSCVDP
FIYYYVSAEFRDKV
>PSYR_HUMAN
LDHYLFPIVYIFVIIVSIPANIGSLCVSFLQAK---SELGIYLFSLSLSDLLYALTLPLW
IDYTW---WTFSPALCKGSAFLMYMNFYSSTAFLTCIAVDRYLAVVYPLK---RTRRFAL
MVSLSIWILETIFNAVMLWE---WQINLNLFRTCTGYAIPLVTILICNRKVYQAV---AT
ENKEKKRIIKLLVSITVTFVLCFTPFHVMLLIRCIL---RTYTMYRITVALTSLNCVADP
ILYCFVTETGRYDM
>PTAFR_HUMAN
FRYTLFPIVYSIIFVLGVIANGYVLWVFARLYP---NEIKIFMVNLTMADMLFLITLPLW
IVYYQ---WILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIK---NTRKRGI
SLSLVIWVAIVGAASYFLIL---GSVPVLIIHIFIVFSFFLVFLIILFCNLVIIR---QR
NAEVKRRALWMVCTVLAVFIICFVPHHVVQLPWTLA---AINDAHQVTLCLLSTNCVLDP
VIYCFLTKKFRKHL
>Q5KU21_HUMAN
SVNNFFIIYSALLLVLGLLLNSVALWVFCYRMH---TETRIYMTNLAVADLCLLCSLPFV
LYSLK---SSSDTPVCQLSQGIYLANRYMSISLVTAIAVDRYVAVRHPLR---RSPRQAA
AVCVALWVIVVTSLVVRWRL---RRNFSTTAFSLLGFYLPLAIVVFCSLQVVTVL---VG
QAEATQKATHMVWANLAVFVICFLPLHVVLTVQVSL---TFSRALSITGKLSDTNCCLDA
ICYYYMAREFQEAS
>SUCR1_HUMAN
LEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLK---NSSNIYLFNLSVSDLAFLCTLPML
IRSYA---WIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFR---QKKEFAI
LISLAIWVLVTLELLPILPL---YNLIYSMCLTLLGFLIPLFVMCFFYYKIALFL---VA
TALPLEKPLNLVIMAVVIFSVLFTPYHVMRNVRIAS---VINSFYIVTRPLAFLNSVINP
VFYFLLGDHFRDML
>AGTR1_HUMAN
YIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMK---TVASVFLLNLALADLCFLLTLPLW
AVYTA---WPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMK---RTMLVAK
VTCIIIWLLAGLASLPAIIH---LPIGLGLTKNILGFLFPFLIILTSYTLIWKAL---QK
NKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLI---IVDTAMPITICIAYFNNCLNP
LFYGFLGKKFKRYF
>AGTR2_HUMAN
KHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKG---KVSSIYIFNLAVADLLLLATLPLW
ATYYS---WLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFL---RNPWQAS
YIVPLVWCMACLSSLPTFYF---WSAGIALMKNILGFIIPLIFIATCYFGIRKHL---GK
NRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALA---VIDLALPFAILLGFTNSCVNP
FLYCFVGNRFQQKL
>APJ_HUMAN
SSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSR---RSADIFIASLAVADLTFVVTLPLW
ATYTY---WPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVA---RLRVSGA
VATAVLWVLAALLAMPVMVL---WEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTI---IE
GLRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLG---FLMNIFPYCTCISYVNSCLNP
FLYAFFDPRFRQAC
>BKRB1_HUMAN
LLHRVLPTFIISICFFGLLGNLFVLLVFLLPRR---NVAEIYLANLAASDLVFVLGLPFW
AENIW---WPFGALLCRVINGVIKANLFISIFLVVAISQDRYRVLVHPMA---QRRRQAR
VTCVLIWVVGGLLSIPTFLL---WHFARIVELNILGFLLPLAAIVFFNYHILASL---RV
RGPKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLF---FIDLGLQLANFFAFTNSSLNP
VIYVFVGRLFRTKV
>BKRB2_HUMAN
WLNTIQPPFLWVLFVLATLENIFVLSVFCLHKS---TVAEIYLGNLAAADLILACGLPFW
AITIS---WLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMS---RGVRWAK
LYSLVIWGCTLLLSSPMLVF---WEVFTNMLLNVVGFLLPLSVITFCTMQIMQVL---FK
EIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLH---IIDVITQIASFMAYSNSCLNP
LVYVIVGKRFRKKS
>C3AR_HUMAN
PPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQ---TVNTIWFLHLTLADLLCCLSLPFS
LAHLA---WPYGRFLCKLIPSIIVLNMFASVFLLTAISLDRCLVVFKPIW---RNVGMAC
SICGCIWVVAFVMCIPVFVY---RLDPSSFQTNDHPWTVPTVFQPQTFQRPSADS---GR
FAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLT---TLMSWDHVCIALASANSCFNP
FLYALLGKDFRKKA
>C5ARL_HUMAN
PLRVAPLPLYAAIFLVGVPGNAMVAWVAGKVAR---RVGATWLLHLAVADLLCCLSLPIL
AVPIA---WPYGAVGCRALPSIILLTMYASVLLLAALSADLCFLALGPAW---QRACGVQ
VACGAAWTLALLLTVPSAIY---TENAVTAIRFLFGFLGPLVAVASCHSALLCWA-----
----ARRCRPLGTAIVVGFFVCWAPYHLLGLVLTVA---RALRAEPLIVGLALAHSCLNP
MLFLYFGRAQLRRS
>C5AR_HUMAN
VPDILALVIFAVVFLVGVLGNALVVWVTAFEAK---TINAIWFLNLAVADFLSCLALPIL
FTSIV---WPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPIW---RGAGLAW
IACAVAWGLALLLTIPSFLY---RERAVAIVRLVLGFLWPLLTLTICYTFILLRT---SR
RATRSTKTLKVVVAVVASFFIFWLPYQVTGIMMSFL---LLNKLDSLCVSFAYINCCINP
IIYVVAGQGFQGRL
>CCBP2_HUMAN
FGKVFLPVFYSLIFVLGLSGNLLLLMVLLRYVP---RMVEIYLLNLAISNLLFLVTLPFW
GISVA---WVFGSFLCKMVSTLYTINFYSGIFFISCMSLDKYLEIVHAQP---RTRAKSL
LLATIVWAVSLAVSIPDMVF---WKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVL---RL
RPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLL---HLDYALQVTESIAFLHCCFSP
ILYAFSSHRFRQYL
>CCR10_HUMAN
FSRAFQPSVSLTVAALGLAGNGLVLATHLAARR---SPTSAHLLQLALADLLLALTLPFA
AAGAL---WSLGSATCRTISGLYSASFHAGFLFLACISADRYVAIARALP---STPGRAH
LVSVIVWLLSLLLALPALLF---VKGASAVAQVALGFALPLGVMVACYALLGRTL---AA
RGPERRRALRVVVALVAAFVVLQLPYSLALLLDTAD---RKDVALLVTSGLALARCGLNP
VLYAFLGLRFRQDL
>CCR1_HUMAN
FGAQLLPPLYSLVFVIGLVGNILVVLVLVQYKR---NMTSIYLLNLAISDLLFLFTLPFW
IDYKL---WVFGDAMCKILSGFYYTGLYSEIFFIILLTIDRYLAIVHAVF---RTVTFGV
ITSIIIWALAILASMPGLYF---WKLFQALKLNLFGLVLPLLVMIICYTGIIKIL---RR
PNEKKSKAVRLIFVIMIIFFLFWTPYNLTILISVFQ---HLDLAVQVTEVIAYTHCCVNP
VIYAFVGERFRKYL
>CCR2_HUMAN
IGAQLLPPLYSLVFIFGFVGNMLVVLILINCKK---CLTDIYLLNLAISDLLFLITLPLW
AHSAA---WVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVF---RTVTFGV
VTSVITWLVAVFASVPGIIF---WNNFHTIMRNILGLVLPLLIMVICYSGILKTL---CR
NEKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQ---QLDQATQVTETLGMTHCCINP
IIYAFVGEKFRSLF
>CCR3_HUMAN
LMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRR---IMTNIYLLNLAISDLLFLVTLPFW
IHYVR---WVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVF---RTVTFGV
ITSIVTWGLAVLAALPEFIF---WRHFHTLRMTIFCLVLPLLVMAICYTGIIKTL---RC
PSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQ---HLDLVMLVTEVIAYSHCCMNP
VIYAFVGERFRKYL
>CCR4_HUMAN
FGELFLPPLYSLVFVFGLLGNSVVVLVLFKYKR---SMTDVYLLNLAISDLLFVFSLPFW
GYYAA---WVFGLGLCKMISWMYLVGFYSGIFFVMLMSIDRYLAIVHAVF---RTLTYGV
ITSLATWSVAVFASLPGFLF---WKVLSSLEINILGLVIPLGIMLFCYSMIIRTL---HC
KNEKKNKAVKMIFAVVVLFLGFWTPYNIVLFLETLV---YLDYAIQATETLAFVHCCLNP
IIYFFLGEKFRKYI
>CCR5_HUMAN
IAARLLPPLYSLVFIFGFVGNMLVILILINCKR---SMTDIYLLNLAISDLFFLLTVPFW
AHYAA---WDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVF---RTVTFGV
VTSVITWVVAVFASLPGIIF---WKNFQTLKIVILGLVLPLLVMVICYSGILKTL---CR
NEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQ---RLDQAMQVTETLGMTHCCINP
IIYAFVGEKFRNYL
>CCR6_HUMAN
FSRLFVPIAYSLICVFGLLGNILVVITFAFYKK---SMTDVYLLNMAIADILFVLTLPFW
AVSHA---WVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATK---RTLPRSK
IICLVVWGLSVIISSSTFVF---WKLLMLGLELLFGFFIPLMFMIFCYTFIVKTL---QA
QNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAAN---LIGYTKTVTEVLAFLHCCLNP
VLYAFIGQKFRNYF
>CCR7_HUMAN
FKAWFLPIMYSIICFVGLLGNGLVVLTYIYFKR---TMTDTYLLNLAVADILFLLTLPFW
AYSAA---WVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVS---RVLLISK
LSCVGIWILATVLSIPELLY---AFITIQVAQMVIGFLVPLLAMSFCYLVIIRTL---QA
RNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVA---QLNIAYDVTYSLACVRCCVNP
FLYAFIGVKFRNDL
>CCR8_HUMAN
NGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKK---SITDVYLLNLALSDLLFVFSFPFQ
TYYLL---WVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVY---RTIRMGT
TLCLAVWLTAIMATIPLLVF---WKIFTNFKMNILGLLIPFTIFMFCYIKILHQL---RC
QNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLH---QLTYATHVTEIISFTHCCVNP
VIYAFVGEKFKKHL
>CCR9_HUMAN
FASHFLPPLYWLVFIVGALGNSLVILVYWYCTR---TMTDMFLLNLAIADLLFLVTLPFW
AIAAA---WKFQTFMCKVVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMR---KRLLYSK
MVCFTIWVLAAALCIPEILY---LKSAVLTLKVILGFFLPFVVMACCYTIIIHTL---QA
KKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTID---NIDICFQVTQTIAFFHSCLNP
VLYVFVGERFRRDL
>CCRL1_HUMAN
FAKVFLPVFLTIVFVIGLAGNSMVVAIYAYYKK---TKTDVYILNLAVADLLLLFTLPFW
AVNAV---WVLGKIMCKITSALYTLNFVSGMQFLACISIDRYVAVTKVPS---GVGKPCW
IICFCVWMAAILLSIPQLVF---MKALIQMLEICIGFVVPFLIMGVCYFITARTL---KM
PNIKISRPLKVLLTVVIVFIVTQLPYNIVKFCRAID---RMDIAIQVTESIALFHSCLNP
ILYVFMGASFKNYV
>CCRL2_HUMAN
LSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKG---RVENIYLLNLAVSNLCFLLTLPFW
AHAG-------GDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGN---RRVPCGI
ITSVLAWVTAILATLPEYVV---WKHFLTLKMNISVLVLPLFIFTFLYVQMRKTL----R
FREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFK---NLDKSVHITKLIATTHCCINP
LLYAFLDGTFSKYL
>CML1_HUMAN
VTRIFLVVVYSIVCFLGILGNGLVIIIATFKMK---TVNMVWFLNLAVADFLFNVFLPIH
ITYAA---WVFGTAMCKISNFLLIHNMFTSVFLLTIISSDRCISVLLPVW---RSVRLAY
MACMVIWVLAFFLSSPSLVF---RHMVVTVTRFLCGFLVPVLIITACYLTIVCKL---RN
RLAKTKKPFKIIVTIIITFFLCWCPYHTLNLLELHH---VFSLGLPLATALAIANSCMNP
ILYVFMGQDFKKFK
>CX3C1_HUMAN
FGTVFLSIFYSVIFAIGLVGNLLVVFALTNSKK---SVTDIYLLNLALSDLLFVATLPFW
THYLI---KGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAAN---RTVQHGV
TISLGVWAAAILVAAPQFMF---WPVLRNVETNFLGFLLPLLIMSYCYFRIIQTL---SC
KNHKKAKAIKLILLVVIVFFLFWTPYNVMIFLETLK---DLRLALSVTETVAFSHCCLNP
LIYAFAGEKFRRYL
>CXCR1_HUMAN
LNKYVVIIAYALVFLLSLLGNSLVMLVILYSRV---SVTDVYLLNLALADLLFALTLPIW
AASKV---WIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATR---QKRHLVK
FVCLGCWGLSMNLSLPFFLF---WRMVLRILPHTFGFIVPLFVMLFCYGFTLRTL---KA
HMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLM---NIGRALDATEILGFLHSCLNP
IIYAFIGQNFRHGF
>CXCR2_HUMAN
INKYFVVIIYALVFLLSLLGNSLVMLVILYSRV---SVTDVYLLNLALADLLFALTLPIW
AASKV---WIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATR---QKRYLVK
FICLSIWGLSLLLALPVLLF---WRMLLRILPQSFGFIVPLLIMLFCYGFTLRTL---KA
HMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLM---HIDRALDATEILGILHSCLNP
LIYAFIGQKFRHGL
>CXCR3_HUMAN
FDRAFLPALYSLLFLLGLLGNGAVAAVLLSRRT---SSTDTFLLHLAVADTLLVLTLPLW
AVDAA---WVFGSGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQ---GPPARVT
LTCLAVWGLCLLFALPDFIF---GRTALRVLQLVAGFLLPLLVMAYCYAHILAVL---VS
RGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILM---RVDVAKSVTSGLGYMHCCLNP
LLYAFVGVKFRERM
>CXCR4_HUMAN
FNKIFLPTIYSIIFLTGIVGNGLVILVMGYQKK---SMTDKYRLHLSVADLLFVITLPFW
AVDAV---WYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATN---RKLLAEK
VVYVGVWIPALLLTIPDFIF---WVVVFQFQHIMVGLILPGIVILSCYCIIISKL---HS
KGHQKRKALKTTVILILAFFACWLPYYIGISIDSFI---TVHKWISITEALAFFHCCLNP
ILYAFLGAKFKTSA
>CXCR5_HUMAN
FKAVFVPVAYSLIFLLGVIGNVLVLVILERHRQ---SSTETFLFHLAVADLLLVFILPFA
VAEGS---WVLGTFLCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVH---RRLLSIH
ITCGTIWLVGFLLALPEILF---AWFTSRFLYHVAGFLLPMLVMGWCYVGVVHRL---AQ
RRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLDTLA---SLPVAITMCEFLGLAHCCLNP
MLYTFAGVKFRSDL
>CXCR6_HUMAN
FSKVFLPCMYLVVFVCGLVGNSLVLVISIFYHK---SLTDVFLVNLPLADLVFVCTLPFW
AYAGI---WVFGQVMCKSLLGIYTINFYTSMLILTCITVDRFIVVVKATK---KRMTWGK
VTSLLIWVISLLVSLPQIIY---ISTVVLATQMTLGFFLPLLTMIVCYSVIIKTL---HA
GGFQKHRSLKIIFLVMAVFLLTQMPFNLMKFIRSTH---SFHYTIMVTEAIAYLRACLNP
VLYAFVSLKFRKNF
>CXCR7_HUMAN
VLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKT---YDTHCYILNLAIADLWVVLTIPVW
VVSLV---WPMGELTCKVTHLIFSINLFGSIFFLTCMSVDRYLSITYFTN---RKKMVRR
VVCILVWLLAFCVSLPDTYY---WLIGMELVSVVLGFAVPFSIIAVFYFLLARAI---AS
SDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFS---ALFTALHVTQCLSLVHCCVNP
VLYSFINRNYRYEL
>FPR1_HUMAN
FLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMT---TVTTISYLNLAVADFCFTSTLPFF
MVRKA---WPFGWFLCKFLFTIVDINLFGSVFLIALIALDRCVCVLHPVW---RTVSLAK
KVIIGPWVMALLLTLPVIIR---MLTVRGIIRFIIGFSAPMSIVAVSYGLIATKI---KQ
GLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVR---EIGIAVDVTSALAFFNSCLNP
MLYVFMGQDFRERL
>FPR2_HUMAN
VLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMT---TVTTICYLNLALADFSFTATLPFL
IVSMA---WPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVW---RTVSLAM
KVIVGPWILALVLTLPVFLF---MLTARGIIRFVIGFSLPMSIVAICYGLIAAKI---KK
GMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVW---IIDILVNPTSSLAFFNSCLNP
MLYVFVGQDFRERL
>FPR3_HUMAN
VLWIFSLLVHGVTFVFGVLGNGLVIWVAGFRMT---TVNTICYLNLALADFSFSAILPFR
MVSVA---WPFGSFLCKLVHVMIDINLFVSVYLITIIALDRCICVLHPAW---RTMSLAK
RVMTGLWIFTIVLTLPNFIF---MAKVFLILHFIIGFSVPMSIITVCYGIIAAKI---RN
HMIKSSRPLRVFAAVVASFFICWFPYELIGILMAVW---IILVLINPTSSLAFFNSCLNP
ILYVFMGRNFQERL
>GP152_HUMAN
PQGGWDTVFLVALLLLGLPANGLMAWLAGSQAR---TRLALLLLSLALSDFLFLAAAAFQ
ILEIR---WPLGTAACRFYYFLWGVSYSSGLFLLAALSLDRCLLALCPHW---RPVRLPL
WVCAGVWVLATLFSVPWLVF---SEELSLRMLEVLGGFLPFLLLLVCHVLTQATA---QQ
QPAACRGFARVARTILSAYVVLRLPYQLAQLLYLAF---LLWEALVYSDYLILLNSCLSP
FLCLMASADLRTLL
>GP182_HUMAN
TKRVVLFALYLAMFVVGLVENLLVICVNWRGSG---GLMNLYILNMAIADLGIVLSLPVW
MLEVT---WLWGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASP---YQHRVRR
AMCAGIWVLSAIIPLPEVVH---WALAVALSTTILGFLLPFPLITVFNVLTACRL---QP
GQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLH---LLYFFYDVIDCFSMLHCVINP
ILYNFLSPHFRGRL
>GPER_HUMAN
IGLFLSCLYTIFLFPIGFVGNILILVVNISFRE---TIPDLYFINLAVADLILVADSLIE
VFNLH---YYDIAVLCTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMR---RTKHHAR
LSCGLIWMASVSATLVPFTA---DVREVQWLEVTLGFIVPFAIIGLCYSLIVRVL---RG
LRPRRQKALRMILAVVLVFFVCWLPENVFISVHLLQ---AHPLTGHIVNLAAFSNSCLNP
LIYSFLGETFRDKL
>GPR15_HUMAN
YTSVFLPVFYTAVFLTGVLGNLVLMGALHFKPG---RLIDIFIINLAASDFIFLVTLPLW
VDKEA---WRTGSFLCKGSSYMISVNMHCSVLLLTCMSVDRYLAIVWPVV---RRTDCAY
VVCASIWFISCLLGLPTLLS---IKLIWSLVALIFTFFVPLLSIVTCYCCIARKL---GK
HNKKLKKSIKIIFIVVAAFLVSWLPFNTFKFLAIVS---ILQLGMEVSGPLAFANSCVNP
FIYYIFDSYIRRAI
>GPR1_HUMAN
VVHWVSLVLYCLAFVLGIPGNAIVIWFTGLKWK---TVTTLWFLNLAIADFIFLLFLPLY
ISYVA---WPFGIWLCKANSFTAQLNMFASVFFLTVISLDHYIHLIHPVL---RTLKNSL
IVIIFIWLLASLIGGPALYF---RHHVLTWVKFIIGYLFPLLTMSICYLCLIFKV---KR
TVLISSRHFWTILVVVVAFVVCWTPYHLFSIWELTI---VMQAGIPLSTGLAFLNSCLNP
ILYVLISKKFQARF
>GPR25_HUMAN
YGYVYIPALYLAAFAVGLLGNAFVVWLLAGRRG---RLVDTFVLHLAAADLGFVLTLPLW
AAAAA---WPFGDGLCKLSSFALAGTRCAGALLLAGMSVDRYLAVVKLLE---RTPRCAL
ASCCGVWAVALLAGLPSLVY---AFQGLSLLLLLLTFVLPLVVTLFCYCRISRRL---PH
VGRARRNSLRIIFAIESTFVGSWLPFSALRAVFHLA---ALRWGLTIATCLAFVNSCANP
LIYLLLDRSFRARA
>GPR32_HUMAN
SLRPLTVVILSASIVVGVLGNGLVLWMTVFRMA---TVSTVCFFHLALADFMLSLSLPIA
MYYIV---WLLGEWACKLYITFVFLSYFASNCLLVFISVDRCISVLYPVW---RTVQRAS
WLAFGVWLLAAALCSAHLKF---GHIIGTIGHFLLGFLGPLAIIGTCAHLIRAKL---RE
GWVHANRPKRLLLVLVSAFFIFWSPFNVVLLVHLWR---RMLLILQASFALGCVNSSLNP
FLYVFVGRDFQEKF
>GPR33_HUMAN
ASKMIIALSLYISSIIGTITNGLYLWVLRFKMK---TVNTLLFFHLILSYFISTMILPFM
ATSQL---WNFGTALCKVFNGTLSLGMFTSVFFLSAIGLDRYLLTLHPVW---RTPRWAS
SIVLGVWISAAALSIPYLIF---IHVACFISRFLLGFLLPFFIIIFCYERVASKV---ER
SLFKSSKPFKVMMTAIISFFVCWMPYHIHQGLLLTT---LLELTLILTVLTTSFNTIFSP
TLYLFVGENFKKVF
>GPR44_HUMAN
YIDHAAVLLHGLASLLGLVENGVILFVVGCRMR---TVVTTWVLHLALSDLLASASLPFF
TYFLA---WELGTTFCKLHSSIFFLNMFASGFLLSAISLDRCLQVVRPVW---RTVAAAH
KVCLVLWALAVLNTVPYFVF---RQAALAVSKFLLAFLVPLAIIASSHAAVSLRL---HR
GRRRPGRFVRLVAAVVAAFALCWGPYHVFSLLEARA---LVWRGLPFVTSLAFFNSVANP
VLYVLTCPDMLRKL
>LT4R1_HUMAN
FISLLAIILLSVALAVGLPGNSFVVWSILKRMQ---SVTALMVLNLALADLAVLLTAPFF
LHFLA---WSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFV---RTKAMAR
RVLAGIWVLSFLLATPVLAY---HRAFHLIFEAVTGFLLPFLAVVASYSDIGRRL---AR
RFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGR---RLSLARNVLIALAFLSSSVNP
VLYACAGGGLLRSA
>LT4R2_HUMAN
TSRATGTAFLLLAALLGLPGNGFVVWSLAGWRP---PLAATLVLHLALADGAVLLLTPLF
VAFLT---WPLGQAGCKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFL---RSPALAR
RLLLAVWLAALLLAVPAAVY---HAAAHLSLETLTAFVLPFGLMLGCYSVTLARL---WG
SGRHGARVGRLVSAIVLAFGLLWAPYHAVNLLQAVA---AGQAARAGTTALAFFSSSVNP
VLYVFTAGDLLPRA
>RL3R1_HUMAN
RVRILISVVYWVVCALGLAGNLLVLYLMKSMQG---SSINLFVTNLALTDFQFVLTLPFW
AVENA---WPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALK---SCCFSAK
ALCVWIWALAALASLPSAIF---WLGLYHSQKVLLGFVLPLGIIILCYLLLVRFI---GA
SARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILI---CQVYAFPVSVCLAHSNSCLNP
VLYCLVRREFRKAL
>RL3R2_HUMAN
ALRLMVALAYGLVGAIGLLGNLAVLWVLSNCAR---PPSDTFVFNLALADLGLALTLPFW
AAESA---WPFGGALCKMVLTATVLNVYASIFLITALSVARYWVVAMAAG---LSLFWAR
IATLAVWAAAALVTVPTAVF---WLGAYQLQRVVLAFMVPLGVITTSYLLLLAFL---QR
RRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLV---IQTYVFPVTTCLAHSNSCLNP
VLYCLLRREPRQAL
>XCR1_HUMAN
FATLATTVLYCLVFLLSLVGNSLVLWVLVKYES---SLTNIFILNLCLSDLVFACLLPVW
ISPYH---WVLGDFLCKLLNMIFSISLYSSIFFLTIMTIHRYLSVVSPLS---PTLRCRV
LVTMAVWVASILSSILDTIF---WYLTSVYQHNLF-FLLSLGIILFCYVEILRTL---RS
RSKRRHRTVKLIFAIVVAYFLSWGPYNFTLFLQTLF---QLEYALLICRNLAFSHCCFNP
VLYVFVGVKFRTHL
>MCHR1_HUMAN
YINIIMPSVFGTICLLGIIGNSTVIFAVVKKSK---NVPDIFIINLSVVDLLFLLGMPFM
IHQLM---WHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPIS---RKPSVAT
LVICLLWALSFISITPVWLY---DLYWFTLYQFFLAFALPFVVITAAYVRILQRM---RS
IRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSI---TFVYLYNAAISLGYANSCLNP
FVYIVLCETFRKRL
>MCHR2_HUMAN
VDTVILPSMIGIICSTGLVGNILIVFTIIRSRK---TVPDIYICNLAVADLVHIVGMPFL
IHQWA---WVFGGPLCTIITSLDTCNQFACSAIMTVMSVDRYFALVQPFR---RTRYKTI
RINLGLWAASFILALPVWVY---DVLWYTLYLTITTFFFPLPLILVCYILILCYT---SV
PKQRVMKLTKMVLVLVVVFILSAAPYHVIQLVNLQM---AFYVGYYLSICLSYASSSINP
FLYILLSGNFQKRL
>NPBW1_HUMAN
PLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPR---TVTNLFILNLAIADELFTLVLPIN
IADFL---WPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAE---RTYSAAR
AVSLAVWGIVTLVVLPFAVF---WWRASRLYTLVLGFAIPVSTICVLYTTLLCRL---KA
LERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTT---LVIAISYFITSLTYANSCLNP
FLYAFLDASFRRNL
>NPBW2_HUMAN
FLYVLLPAVYSGICAVGLTGNTAVILVILRAPK---TVTNVFILNLAVADGLFTLVLPVN
IAEHL---WPFGELLCKLVLAVDHYNIFSSIYFLAVMSVDRYLVVLATVR---RTYRGAK
VASLCVWLGVTVLVLPFFSF---WFKASRVYTLVLGFVLPVCTICVLYTDLLRRL---KA
LGKARRKVTVLVLVVLAVCLLCWTPFHLASVVALTT---LVISMSYVITSLTYANSCLNP
FLYAFLDDNFRKNF
>OPRD_HUMAN
ALAIAITALYSAVCAVGLLGNVLVMFGIVRYTK---TATNIYIFNLALADALATSTLPFQ
SAKYL---WPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVK---RTPAKAK
LINICIWVLASGVGVPIMVM---WDTVTKICVFLFAFVVPILIITVCYGLMLLRL---KE
KDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLV---LVVAALHLCIALGYANSSLNP
VLYAFLDENFKRCF
>OPRK_HUMAN
AIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTK---TATNIYIFNLALADALVTTTMPFQ
STVYL---WPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVK---RTPLKAK
IINICIWLLSSSVGISAIVL---WDLFMKICVFIFAFVIPVLIIIVCYTLMILRL---RE
KDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG---AALSSYYFCIALGYTNSSLNP
ILYAFLDENFKRCF
>OPRM_HUMAN
ITAITIMALYSIVCVVGLFGNFLVMYVIVRYTK---TATNIYIFNLALADALATSTLPFQ
SVNYL---WPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK---RTPRNAK
IINVCNWILSSAIGLPVMFM---WENLLKICVFIFAFIMPVLIITVCYGLMILRL---KE
KDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALV---FQTVSWHFCIALGYTNSCLNP
VLYAFLDENFKRCF
>OPRX_HUMAN
GLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTK---TATNIYIFNLALADTLVLLTLPFQ
GTDIL---WPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIR---RTSSKAQ
AVNVAIWALASVVGVPVAIM---WGPVFAICIFLFSFIVPVLVISVCYSLMIRRL---RE
KDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLG---TAVAILRFCTALGYVNSCLNP
ILYAFLDENFKACF
>SSR1_HUMAN
GSAILISFIYSVVCLVGLCGNSMVIYVILRYAK---TATNIYILNLAIADELLMLSVPFL
VTSTL---WPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIK---RRPTVAK
VVNLGVWVLSLLVILPIVVF---WLVGFVLYTFLMGFLLPVGAICLCYVLIIAKM---QQ
RKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFA---DDATVSQLSVILGYANSCANP
ILYGFLSDNFKRSF
>SSR2_HUMAN
TSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAK---TITNIYILNLAIADELFMLGLPFL
AMQVA---WPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIK---RRPRTAK
MITMAVWGVSLLVILPIMIY---WYTGFIIYTFILGFLVPLTIICLCYLFIIIKV---SK
RKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSM---ALKGMFDFVVVLTYANSCANP
ILYAFLSDNFKKSF
>SSR3_HUMAN
VSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTA---SVTNVYILNLALADELFMLGLPFL
AAQNA---WPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTR---RTAPVAR
TVSAAVWVASAVVVLPVVVF---WRAGFIIYTAALGFFGPLLVICLCYLLIVVKV---QR
RRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVC---AFFGLYFLVVALPYANSCANP
ILYGFLSYRFKQGF
>SSR4_HUMAN
AGMVAIQCIYALVCLVGLVGNALVIFVILRYAK---TATNIYLLNLAVADELFMLSVPFV
ASSAA---WPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLR---RRPSVAK
LINLGVWLASLLVTLPIAIF---WSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKM---QQ
RRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLVV---LDATVNHVSLILSYANSCANP
ILYGFLSDNFRRSF
>SSR5_HUMAN
ARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAK---TVTNIYILNLAVADVLYMLGLPFL
ATQNA---WPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLS---RRPRVAK
LASAAAWVLSLCMSLPLLVF---WGAVFIIYTAVLGFFAPLLVICLCYLLIVVKV---CV
RRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAV---ASAGLYFFVVILSYANSCANP
VLYGFLSDNFRQSF
>UR2R_HUMAN
VATGTIGTLLSAMGVVGVVGNAYTLVVTCRSLR---ASMYVYVVNLALADLLYLLSIPFI
VATYV---WHFGDVGCRVLFGLDFLTMHASIFTLTVMSSERYAAVLRPLD---RPKGYRK
LLALGTWLLALLLTLPVMLA---AHRAYLTLLFATSIAGPGLLIGLLYARLARAY---KR
ARRPGARALRLVLGIVLLFWACFLPFWLWQLLAQYH---TARIVNYLTTCLTYGNSCANP
FLYTLLTRNYRDHL
>BRS3_HUMAN
EALCAIYITYAVIISVGILGNAILIKVFFKTKS---TVPNIFITSLAFGDLLLLLTCVPV
DATHY---WLFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLE---NAILKTC
VKAGCVWIVSMIFALPEAIF---LQEIHSLLCFLVFYIIPLSIISVYYSLIARTL---RK
QIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFT---MHFIFTIFSRVLAFSNSCVNP
FALYWLSKSFQKHF
>CCKAR_HUMAN
WQPAVQILLYSLIFLLSVLGNTLVITVLIRNKR---TVTNIFLLSLAVSDLMLCLFCMPF
NLIPN---FIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQ---QTKSHAL
KVIAATWCLSFTIMTPYPIY---MQQSWHTFLLLILFLIPGIVMMVAYGLISLEL---AA
NLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYD---LSGTPISFILLLSYTSSCVNP
IIYCFMNKRFRLGF
>EDNRA_HUMAN
AFKYINTVISCTIFIVGMVGNATLLRIIYQNKC---NGPNALIASLALGDLIYVVIDLPI
NVFKL---NDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSR---GIPLVTA
IEIVSIWILSFILAIPEAIG---YQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEM---SE
HLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTV---FLLLMDYIGINLATMNSCINP
IALYFVSKKFKNCF
>EDNRB_HUMAN
TFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKC---NGPNILIASLALGDLLHIVIDIPI
NVYKL---WPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSR---GVPKWTA
VEIVLIWVVSVVLAVPEAIG---YKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM---ND
HLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTL---FLLVLDYIGINMASLNSCINP
IALYLVSKRFKNCF
>ETBR2_HUMAN
YSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYY---SAWNSILASLALWDFLVLFFCLPI
VIFNE---RLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLP---ERCQSIL
AKLAVIWVGSMTLAVPELLL---YQNARMWWYFGCYFCLPILFTVTCQLVTWRVR---SK
HEQCESQLNSTVVGLTVVYAFCTLPENVCNIVVAYL---TLDLLGLINQFSTFFKGAITP
VLLLCICRPLGQAF
>GALR1_HUMAN
VENFVTLVVFGLIFALGVLGNSLVITVLARSKP---STTNLFILNLSIADLAYLLFCIPF
QATVY---WVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRR---RVSRNAL
LGVGCIWALSIAMASPVAYH---HKKAYVVCTFVFGYLLPLLLICFCYAKVLNHL---KK
SEASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFG---ASFLFRITAHCLAYSNSSVNP
IIYAFLSENFRKAY
>GALR2_HUMAN
PEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQ---STTNLFILNLGVADLCFILCCVPF
QATIY---WVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLH---RTPRNAL
AAIGLIWGLSLLFSGPYLSY---RRRAMDICTFVFSYLLPVLVLGLTYARTLRYL---SG
ARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFG---ATYALRILSHLVSYANSCVNP
IVYALVSKHFRKGF
>GALR3_HUMAN
VGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGP---STTDLFILNLAVADLCFILCCVPF
QATIY---WLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLR---RTPRNAR
AAVGLVWLLAALFSAPYLSY---RRRALDVATFAAGYLLPVAVVSLAYGRTLRFL---EA
RRRATGRAGRAMLAVAALYALCWGPHHALILCFWYG---ATYACRLASHCLAYANSCLNP
LVYALASRHFRARF
>GASR_HUMAN
LELAIRITLYAVIFLMSVGGNMLIIVVLGLSRR---TVTNAFLLSLAVSDLLLAVACMPF
TLLPN---FIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQ---QTRSHAA
RVIVATWLLSGLLMVPYPVY---VRQTWSVLLLLLLFFIPGVVMAVAYGLISREL---QA
KLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFD---LSGAPISFIHLLSYASACVNP
LVYCFMHRRFRQAC
>GHSR_HUMAN
PLLAGVTATCVALFVVGIAGNLLTMLVVSRFRE---TTTNLYLSSMAFSDLLIFLCMPLD
LVRLW---WNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLR---VTKGRVK
LVIFVIWAVAFCSAGPIFVL---GLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKL---SL
RDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKS---ISQYCNLVSFVLFYLSAAINP
ILYNIMSKKYRVAV
>GNRHR_HUMAN
LSGKIRVTVTFFLFLLSATFNASFLLKLQKWTQ---SRMKLLLKHLTLANLLETLIVMPL
DGMWN---WYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLA---SNSKVGQ
SMVGLAWILSSVFAGPQLYI---HQAFYNFFTFSCLFIIPLFIMLICNAKIIFTL---NN
IPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFD---LSDPVNHFFFLFAFLNPCFDP
LIYGYFSL------
>GNRR2_HUMAN
AAAKVRVGVTIVLFVSSAGGNLAVLWSVTRREP---SPVRRLFIHLAAADLLVTFVVMPL
DATWN---WLAVDIACRTLMFLKLMATYSAAFLPVVIGLDRQAAVLNPL----GSRSGVR
KLLGAAWGLSFLLAFPQLFL---QETTYNLFTFCCLFLLPLTAMAICYSRIVLSV---DN
CPRVRLRALRLALLILLTFILCWTPYYLLGMWYWFS---VPPSLSHILFLLGLLNAPLDP
LLYGAFTLGCRRGH
>GP101_HUMAN
AHGIIRSTVLVIFLAASFVGNIVLALVLQRKPQ---QVTNRFIFNLLVTDLLQISLVAPW
VVATS---WPLNSHFCTALVSLTHLFAFASVNTIVVVSVDRYLSIIHPLS---MTQRRGY
LLLYGTWIVAILQSTPPLYG---ASPSYTILSVVSFIVIPLIVMIACYSVVFCAA---PL
PRCYQCKAAKVIFIIIFSYVLSLGPYCFLAVLAVWV---VPQWVITIIIWLFFLQCCIHP
YVYGYMHKTIKKEI
>GP135_HUMAN
AAVAAQALVLLLIFLLSSLGNCAVMGVIVKHRQ---TVTNAFILSLSLSDLLTALLCLPA
AFLDL---AGPWRGFCAASRFFSSCFGIVSTLSVALISLDRYCAIVRPPR---IGRRRAL
QLLAGAWLTALGFSLPWELL---LGAAFSVGLVVACYLLPFLLMCFCHYHICKTV---VL
RFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAAR---APSLLSVVAVWLTWANGAINP
VIYAIRNPNISMLL
>GP151_HUMAN
DWRTIIPALLVAVCLVGFVGNLCVIGILLHNAW---SMIHSLILNLSLADLSLLLFSAPI
RATAY---WDLGWFVCKSSDWFIHTCMAAKSLTIVVVAKVCFMYASDPAK---IHNYTIW
SVLVAIWTVASLLPLPEWFF---FMSMFGKLYPLLAFGLPLFFASFYFWRAYDQC---LR
NQIRSKQVTVMLLSIAIISALLWLPEWVAWLWVWHL---PPQGFIALSQVLMFSISSANP
LIFLVMSEEFREGL
>GP173_HUMAN
ASAYVKLVLLGLIMCVSLAGNAILSLLVLKERA---KAPYYFLLDLCLADGIRSAVCFPF
VLASV---WTFSALSCKIVAFMAVLFCFHAAFMLFCISVTRYMAIAHHRF---MTLWTCA
AVICMAWTLSVAMAFPPVFD---YFKANDTLGFMLMLAVLMAATHAVYGKLLLFE---MD
EVKGEKQLGRMFYAITLLFLLLWSPYIVACYWRVFV---VPHRYLATAVWMSFAQAAVNP
IVCFLLNKDLKKCL
>GP176_HUMAN
LYRQFTTTVQVVIFIGSLLGNFMVLWSTCRTTV---SVTNRFIKNLACSGICASLVCVPF
DIILS---WIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLE---ISDAKSR
ELVMYIWAHAVVASVPVFAV---GHLVYVLVYNITTVIVPVVVVFLFLILIRRAL---PY
ASQREAELHATLLSMVMVFILCSVPYATLVVYQTVL---TSVFLLLTAVWLPKVSLLANP
VLFLTVNKSVRKCL
>GPR19_HUMAN
GEVATASIFFGILWLFSIFGNSLVCLVIHRSRR---STTNYFVVSMACADLLISVASTPF
VLLQF---WTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLS---VSREKAK
KMIAASWIFDAGFVTPVLFF---EGTAYTVIHFLVGFVIPSVLIILFYQKVIKYI---NI
VPRTKVKTIKMFLILNLLFLLSWLPFHVAQLWHPHE---KSSLVFTAITWISFSSSASKP
TLYSIYNANFRRGM
>GPR27_HUMAN
AALGLKLATLSLLLCVSLAGNVLFALLIVRERS---RAPYYLLLDLCLADGLRALACLPA
VMLAA---APPGALGCKLLAFLAALFCFHAAFLLLGVGVTRYLAIAHHRF---AGWPCAA
MLVCAAWALALAAAFPPVLD---PDGAPGALGFLLLLAVVVGATHLVYLRLLFFI---LE
EFKTEKRLCKMFYAVTLLFLLLWGPYVVASYLRVLV---VPQAYLTASVWLTFAQAGINP
VVCFLFNRELRDCF
>GPR37_HUMAN
YGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYY---SISNSLLANLAFWDFLIIFFCLPL
VIFHE---WLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRFRAATNVQM---ENCSSTT
AKLAVIWVGALLLALPEVVL---YDSARLWWYFGCYFCLPTLFTITCSLVTARKI---KR
QIQLESQMNCTVVALTILYGFCIIPENICNIVTAYM---TMDLLNIISQFLLFFKSCVTP
VLLFCLCKPFSRAF
>GPR39_HUMAN
WIKITLILVYLIIFVMGLLGNSATIRVTQVLQK---KEVTDHMVSLACSDILVFLIGMPM
EFYSI---TSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFR---SGPCQVK
LLIGFVWVTSALVALPLLFA---MSICTNLSSRWTVFQSSIFGAFVVYLVVLLSV---EE
SRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAK---AYMILLPFSETFFYLSSVINP
LLYTVSSQQFRRVF
>GPR83_HUMAN
TVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQR---SATSLFIVNLAVADIMITLLNTPF
TLVRF---WIFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLK---ISITKGV
IYIAVIWTMATFFSLPHAIC---FWKYLDLATFILLYILPLLIISVAYARVAKKL---FA
LRRKKKKTIKMLMLVVVLFALCWFPLNCYVLLLSSK---TNNALYFAFHWFAMSSTCYNP
FIYCWLNENFRIEL
>GPR84_HUMAN
GYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPK---TRFNLLIANLTLADLLYCTLLQPF
SVDTY---WRTGATFCRVFGLLLFASNSVSILTLCLIALGRYLLIAHPKL---FSAKGIV
LALVSTWVVGVASFAPLWPI---RGRPYTTILMGIYFVLGLSSVGIFYCLIHRQV---PD
SSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARV---APRVVHMLAANLTWLNGCINP
VLYAAMNRQFRQAY
>GPR85_HUMAN
LTAFLKLTSLGFIIGVSVVGNLLISILLVKDKT---RAPYYFLLDLCCSDILRSAICFPF
VFNSV---WTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRF---LTFWTCL
AVICMVWTLSVAMAFPPVLD---SFRANDSLGFMLLLALILLATQLVYLKLIFFV---LD
EFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFA---VPGGFLTAAVWMSFAQAGINP
FVCIFSNRELRRCF
>GRPR_HUMAN
GILYVIPAVYGVIILIGLIGNITLIKIFCTVKS---NVPNLFISSLALGDLLLLITCAPV
DASRY---WLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMD---HALMKIC
LKAAFIWIISMLLAIPEAVF---HPKIHSMASFLVFYVIPLSIISVYYYFIAKNL---KK
QIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYH---LHFVTSICARLLAFTNSCVNP
FALYLLSKSFRKQF
>KISSR_HUMAN
VDAWLVPLFFAALMLLGLVGNSLVIYVICRHKP---TVTNFYIANLAATDVTFLLCCVPF
TALLY---WVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLR---RTPRLAL
AVSLSIWVGSAAVSAPVLAL---LERAFALYNLLALYLLPLLATCACYAAMLRHL---ER
AGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALG---AAYALKTWAHCMSYSNSALNP
LLYAFLGSHFRQAF
>MTLR_HUMAN
GALVPVTAVCLCLFVVGVSGNVVTVMLIGRYRD---TTTNLYLGSMAVSDLLILLGLPFD
LYRLW---WVFGPLLCRLSLYVGEGCTYATLLHMTALSVERYLAICRPLR---VTRRRVR
ALIAVLWAVALLSAGPFLFL---GALRVMLWVTTAYFFLPFLCLSILYGLIGREL---SG
RERGHRQTVRVLLVVVLAFIICWLPFHVGRIIYINT---FSQYFNIVALQLFYLSASINP
ILYNLISKKYRAAA
>NK1R_HUMAN
WQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKR---TVTNYFLVNLAFAEASMAAFNTVV
NFTYA---WYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQ---LSATATK
VVICVIWVLALLLAFPQGYY---YEKVYHICVTVLIYFLPLLVIGYAYTVVGITL---HE
QVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN---FIQQVYLAIMWLAMSSTMYNP
IIYCCLNDRFRLGF
>NK2R_HUMAN
WQLALWATAYLALVLVAVTGNAIVIWIILAHRR---TVTNYFIVNLALADLCMAAFNAAF
NFVYA---WYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQ---LSAPSTK
AVIAGIWLVALALASPQCFY---TLLLYHLVVIALIYFLPLAVMFVAYSVIGLTL---LR
HLQAKKKFVKTMVLVVLTFAICWLPYHLYFILGSFQ---FIQQVYLALFWLAMSSTMYNP
IIYCCLNHRFRSGF
>NK3R_HUMAN
WRIALWSLAYGVVVAVAVLGNLIVIWIILAHKR---TVTNYFLVNLAFSDASMAAFNTLV
NFIYA---WYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLK---LSATATK
IVIGSIWILAFLLAFPQCLY---QHFTYHIIVIILVYCFPLLIMGITYTIVGITL---HE
QLKAKRKVVKMMIIVVMTFAICWLPYHIYFILTAIY---YIQQVYLASFWLAMSSTMYNP
IIYCCLNKRFRAGF
>NMBR_HUMAN
VIRCVIPSLYLLIITVGLLGNIMLVKIFITNSA---SVPNIFISNLAAGDLLLLLTCVPV
DASRY---WMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMD---GALLRTC
VKAMGIWVVSVLLAVPEAVF---HPKIHSVLIFLVYFLIPLAIISIYYYHIAKTL---KK
QMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFN---GHMIVTLVARVLSFGNSCVNP
FALYLLSESFRRHF
>NMUR1_HUMAN
ELFMPICATYLLIFVVGAVGNGLTCLVILRHKA---TPTNYYLFSLAVSDLLVLLVGLPL
ELYEM---FLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQ---VTRAHVR
RVLGAVWGLAMLCSLPNTSL---LYNMVVQTTALLFFCLPMAIMSVLYLLIGLRL---QQ
HDRGRRQVTKMLFVLVVVFGICWAPFHADRVMWSVV---AFQHVHVISGIFFYLGSAANP
VLYSLMSSRFRETF
>NMUR2_HUMAN
HFFLPVSVVYVPIFVVGVIGNVLVCLVILQHQA---TPTNYYLFSLAVSDLLVLLLGMPL
EVYEM---FLFGPVGCYFKTALFETVCFASILSITTVSVERYVAILHPFR---STRRRAL
RILGIVWGFSVLFSLPNTSI---IYNFIIQVTSFLFYLLPMTVISVLYYLMALRL---NI
QRPCRKSVNKMLFVLVLVFAICWAPFHIDRLFFSFV---VFNLVHVVSGVFFYLSSAVNP
IIYNLLSRRFQAAF
>NPFF1_HUMAN
PVAAMFIVAYALIFLLCMVGNTLVCFIVLKNRH---TVTNMFILNLAVSDLLVGIFCMPT
TLVDN---WPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFR---LTLRKAL
VTIAVIWALALLIMCPSAVT---MRRVYTTVLFSHIYLAPLALIVVMYARIARKL---PR
ASRRRARVVHMLVMVALFFTLSWLPLWALLLLIDYG---VTVYAFPFAHWLAFFNSSANP
IIYGYFNENFRRGF
>NPFF2_HUMAN
QVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKH---TVTNLFILNLAISDLLVGIFCMPI
TLLDN---WPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFK---LTIKTAF
VIIMIIWVLAITIMSPSAVM---MRKIYTTVLFANIYLAPLSLIVIMYGRIGISL---HV
VSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYA---INIYIYPFAHWLAFGNSSVNP
IIYGFFNENFRRGF
>NPSR1_HUMAN
SFKTEQLITLWVLFVFTIVGNSVVLFSTWRRKK---SRMTFFVTQLAITDSFTGLVNILT
DINWR---FTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMK---QGEKQAR
VLIVIAWSLSFLFSIPTLII---YWTPYMTIVAFLVYFIPLTIISIMYGIVIRTI---GL
ISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFN---ERFYASVIIQNLPALNSAINP
LIYCVFSSSISFPC
>NPY1R_HUMAN
AMIFTLALAYGAVIILGVSGNLALIIIILKQKE---NVTNILIVNLSFSDLLVAIMCLPF
TFVYT---WVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRG---PNNRHAY
VGIAVIWVLAVASSLPFLIY---HRLSYTTLLLVLQYFGPLCFIFICYFKIYIRL---KY
RSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWN---NHNLLFLLCHLTAMISTCVNP
IFYGFLNKNFQRDL
>NPY2R_HUMAN
EVQVVLILAYCSIILLGVIGNSLVIHVVIKFKS---TVTNFFIANLAVADLLVNTLCLPF
TLTYT---WKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLE---ISKRISF
LIIGLAWGISALLASPLAIF---YGTVYSLSSLLILYVLPLGIISFSYTRIWSKL---DH
YHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDID---EYKLIFTVFHIIAMCSTFANP
LLYGWMNSNYRKAF
>NPY4R_HUMAN
DVMVFIVTSYSIETVVGVLGNLCLMCVTVRQKE---NVTNLLIANLAFSDFLMCLLCQPL
TAVYT---WIFGETLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTG---PSISQAY
LGIVLIWVIACVLSLPFLAN---HRTIYTTFLLLFQYCLPLGFILVCYARIYRRL---SL
RAGHMKQVNVVLVVMVVAFAVLWLPLHVFNSLEDWH---HGNLIFLVCHLLAMASTCVNP
FIYGFLNTNFKKEI
>NPY5R_HUMAN
DLQYFLIGLYTFVSLLGFMGNLLILMALMKKRN---TTVNFLIGNLAFSDILVVLFCSPF
TLTSV---WMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPIS---LTANHGY
FLIATVWTLGFAICSPLPVF---YRIAFTISLLLVQYILPLVCLTVSHTSVCRSI---TR
IKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFN---HFKLVYCICHLLGMMSCCLNP
ILYGFLNNGIKADL
>NTR1_HUMAN
YSKVLVTAVYLALFVVGTVGNTVTAFTLARKKS---STVHYHLGSLALSDLLTLLLAMPV
ELYNF---WAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFK---MSRSRTK
KFISAIWLASALLTVPMLFT---TVKVVIQVNTFMSFIFPMVVISVLNTIIANKL---PG
RVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYI---FYHYFYMVTNALFYVSSTINP
ILYNLVSANFRHIF
>NTR2_HUMAN
WAKVLFTALYALIWALGAAGNALSVHVVLKARA---GRLRHHVLSLALAGLLLLLVGVPV
ELYSF---WVFGDLGCRGYYFVHELCAYATVLSVAGLSAERCLAVCQPLR---LTPRRTR
WLVALSWAASLGLALPMAVI---ALQVFIQVNVLVSFVLPLALTAFLNGVTVSHL---VR
RIRSLQRSVQVLRAIVVMYVICWLPYHARRLMYCYV---FYHYFYMVTNTLFYVSSAVTP
LLYNAVSSSFRKLF
>OX1R_HUMAN
QYEWVLIAAYVAVFVVALVGNTLVCLAVWRNHH---TVTNYFIVNLSLADVLVTAICLPA
SLLVD---WLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLL---STARRAR
GSILGIWAVSLAIMVPQAAV---YPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKL---VK
QMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVF---AVYACFTFSHWLVYANSAANP
IIYNFLSGKFREQF
>OX2R_HUMAN
EYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHH---TVTNYFIVNLSLADVLVTITCLPA
TLVVD---WFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLM---STAKRAR
NSIVIIWIVSCIIMIPQAIV---YPKMYHICFFLVTYMAPLCLMVLAYLQIFRKL---IK
QIRARRKTARMLMVVLLVFAICYLPISILNVLKRVF---TVYAWFTFSHWLVYANSAANP
IIYNFLSGKFREEF
>OXYR_HUMAN
ALARVEVAVLCLILLLALSGNACVLLALRTTRQ---SRLFFFMKHLSIADLVVAVFQVLP
QLLWD---FYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLR---LRRRTDR
LAVLATWLGCLVASAPQVHI---GPKAYITWITLAVYIVPVIVLATCYGLISFKI---KL
ISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWD---KEASAFIIVMLLASLNSCCNP
WIYMLFTGHLFHEL
>PKR1_HUMAN
AAKIVIGMALVGIMLVCGIGNFIFIAALVRYKK---NLTNLLIANLAISDFLVAIVCCPF
EMDYY---WEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLR---MKCQTAT
GLIALVWTVSILIAIPSAYF---YYKSYFLFIFGIEFVGPVVTMTLCYARISREL---RK
RLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFF---HYLTAFYIVECIAMSNSMINT
LCFVTVKNDTVKYF
>PKR2_HUMAN
AAKIVIGIALAGIMLVCGIGNFVFIAALTRYKK---NLTNLLIANLAISDFLVAIICCPF
EMDYY---WEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLK---MNYQTAS
FLIALVWMVSILIAIPSAYF---YYKSYFLFIFGVEFVGPVVTMTLCYARISREL---RK
RLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFF---HYLTAFYVVECIAMSNSMINT
VCFVTVKNNTMKYF
>PRLHR_HUMAN
QLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRR---NVTNFLIGNLALSDVLMCTACVPL
TLAYA---WVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLR---ISLRLSA
YAVLAIWALSAVLALPAAVH---QRQLYAWGLLLVTYLLPLLVILLSYVRVSVKL---DW
DRARRRRTFCLLVVVVVVFAVCWLPLHVFNLLRDLD---AFGLVQLLCHWLAMSSACYNP
FIYAWLHDSFREEL
>QRFPR_HUMAN
RAKLALVLTGVLIFALALFGNALVFYVVTRSKA---TVTNIFICSLALSDLLITFFCIPV
TMLQN---WLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFK---YTNRRAF
TMLGVVWLVAVIVGSPMWHV---HQKIYTTFILVILFLLPLMVMLILYSKIGYEL---SK
IARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYS---TIKMIFAIVQIIGFSNSICNP
IVYAFMNENFKKNV
>TRFR_HUMAN
EYQVVTILLVLIICGLGIVGNIMVVLVVMRTKH---TPTNCYLVSLAVADLMVLVAAGLP
NITDS---WVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIK---CTFSRAK
KIIIFVWAFTSLYCMLWFFL---YYSPIYLMDFGVFYVVPMILATVLYGFIARIL---NS
TVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFL---QENWFLLFCRICIYLNSAINP
VIYNLMSQKFRAAF
>V1AR_HUMAN
ELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPR---SRMHLFIRHLSLADLAVAFFQVLP
QMCWD---FRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLK---QPARRSR
LMIAAAWVLSFVLSTPQYFV---GSRAYVTWMTGGIFVAPVVILGTCYGFICYNI---KS
ISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWD---SENPTITITALLGSLNSCCNP
WIYMFFSGHLLQDC
>V1BR_HUMAN
ELAKVEIGVLATVLVLATGGNLAVLLTLGQLGR---SRMHLFVLHLALTDLAVALFQVLP
QLLWD---FQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLR---QPGQSTY
LLIAAPWLLAAIFSLPQVFI---GPRAYLTWTTLAIFVLPVTMLTACYSLICHEI---NT
ISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWD---STNVAFTISMLLGNLNSCCNP
WIYMGFNSHLLPRP
>V2R_HUMAN
LLARAELALLSIVFVAVALSNGLVLAALARRGR---APIHVFIGHLCLADLAVALFQVLP
QLAWK---FRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPML---GSGAHWN
RPVLVAWAFSLLLSLPQLFI---GRRTYVTWIALMVFVAPTLGIAACQVLIFREI---AH
VSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWD---LEGAPFVLLMLLASLNSCTNP
WIYASFSSSVSSEL
>MTR1A_HUMAN
WLASALACVLIFTIVVDILGNLLVILSVYRNKK---NAGNIFVVSLAVADLVVAIYPYPL
VLMSI---WNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLK---YSSKNSL
CYVLLIWLLTLAAVLPNLRA---VSSAYTIAVVVFHFLVPMIIVIFCYLRIWILV---PK
LKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASD---IPEWLFVASYYMAYFNSCLNA
IIYGLLNQNFRKEY
>MTR1B_HUMAN
WVAPALSAVLIVTTAVDVVGNLLVILSVLRNRK---NAGNLFLVSLALADLVVAFYPYPL
ILVAI---WALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMA---YRRWHTP
LHICLIWLLTVVALLPNFFV---ASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLV---LC
LKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAIN---IPEGLFVTSYLLAYFNSCLNA
IVYGLLNQNFRREY
>MTR1L_HUMAN
ALIIFMFCAMVITIVVDLIGNSMVILAVTKNKK---NSGNIFVVSLSVADMLVAIYPYPL
MLHAM---WDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQ---FSVRNTC
IYLVITWIMTVLAVLPNMYI---NNPVFTVTIVCIHFVLPLLIVGFCYVRIWTKV---PD
NQLAEVRNFLTMFVIFLLFAVCWCPINVLTVLVAVS---IPNWLYLAAYFIAYFNSCLNA
VIYGLLNENFRREY
>OPN3_HUMAN
GTYERLALLLGSIGLLGVGNNLLVLVLYYKFQR---TPTHLLLVNISLSDLLVSLFGVTF
TFVSC---WVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHARV---INFSWAW
RAITYIWLYSLAWAGAPLLG---NDSSFVLFLFLGCLVVPLGVIAHCYGHILYSI---IK
ILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNG---VTPTISIVSYLFAKSNTVYNP
VIYVFMIRKFRRSL
>OPN4_HUMAN
HAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRS---TPANMFIINLAVSDFLMSFTQAPV
FFTSS---WLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLA---ASKRRAA
FVLLGVWLYALAWSLPPFFG---AVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAI---RQ
RLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAG---LTPYMSSVPAVIAKASAIHNP
IIYAITHPKYRVAI
>OPN5_HUMAN
EADLVAGFYLTIIGILSTFGNGYVLYMSSRRKK---RPAEIMTINLAVCDLGISVVGKPF
TIISC---WVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSY---LKRKHAY
ICLAAIWAYASFWTTMPLVG---GGQVFILNILFFCLLLPTAVIVFSYVKIIAKV---HS
SHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFG---IPIQLSVVPTLLAKSAAMYNP
IIYQVIDYKFACCQ
>OPSB_HUMAN
WAFYLQAAFMGTVFLIGFPLNAMVLVATLRYKK---QPLNYILVNVSFGGFLLCIFSVFP
VFVAS---FVFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFG---FSSKHAL
TVVLATWTIGIGVSIPPFFG---RSESYTWFLFIFCFIVPLSLICFSYTQLLRAL---AT
TQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNN---LDLRLVTIPSFFSKSACIYNP
IIYCFMNKQFQACI
>OPSD_HUMAN
WQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKK---TPLNYILLNLAVADLFMVLGGFTS
TLYTS---FVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS---FGENHAI
MGVAFTWVMALACAAPPLAG---NNESFVIYMFVVHFTIPMIIIFFCYGQLVFTV---AT
TQKAEKEVTRMVIIMVIAFLICWVPYASVAFYIFTH---FGPIFMTIPAFFAKSAAIYNP
VIYIMMNKQFRNCM
>OPSR_HUMAN
WVYHLTSVWMIFVVTASVFTNGLVLAATMKFKK---HPLNWILVNLAVADLAETVIASTI
SIVNQ---FVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFG---FDAKLAI
VGIAFSWIWSAVWTAPPIFG---GVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAI---ES
TQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAAN---FHPLMAALPAYFAKSATIYNP
VIYVFMNRQFRNCI
>OPSX_HUMAN
TEHNIVATYLIMAGMISIISNIIVLGIFIKYKE---TPTNAIIINLAVTDIGVSSIGYPM
SAASD---WKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDV---MTTNTYI
GLILGAWINGLFWALMPIIG---SFVSYTMTVIAINFIVPLTVMFYCYYHVTLSI---NR
DWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASFG---IPPPMAIIAPLFAKSSTFYNP
CIYVVANKKFRRAM
>RGR_HUMAN
LEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPE---TPCHLLVLSLALADSGISLNALVA
ATSSL---WPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQ---LAWNSAV
SLVLFVWLSSAFWAALPLLG---NFTSFLFTMSFFNFAMPLFITITSYSLMEQKL-----
--GKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIA---ISPKLQMVPALIAKMVPTINA
INYALGNEMVCRGI
>FSHR_HUMAN
MGYNILRVLIWFISILAITGNIIVLVILTTSQY---TVPRFLMCNLAFADLCIGIYLLLI
ASVDI---DWQTGAGCDAAGFFTVFASELSVYTLTAITLERWHTITHAMQ---VQLRHAA
SVMVMGWIFAFAAALFPIFG---PLSQLYVMSLLVLNVLAFVVICGCYIHIYLTV---IV
SSSSDTRIAKRMAMLIFTDFLCMAPISFFAISASLK---TVSKAKILLVLFHPINSCANP
FLYAIFTKNFRRDF
>LSHR_HUMAN
MGYDFLRVLIWLINILAIMGNMTVLFVLLTSRY---TVPRFLMCNLSFADFCMGLYLLLI
ASVDS---DWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIH---LRLRHAI
LIMLGGWLFSSLIAMLPLVG---TLSQVYILTILILNVVAFFIICACYIKIYFAV---LM
ATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFK---TVTNSKVLLVLFYPINSCANP
FLYAIFTKTFQRDF
>TSHR_HUMAN
MGYKFLRIVVWFVSLLALLGNVFVLLILLTSHY---NVPRFLMCNLAFADFCMGMYLLLI
ASVDL---DWQTGPGCNTAGFFTVFASELSVYTLTVITLERWYAITFAMR---IRLRHAC
AIMVGGWVCCFLLALLPLVG---PLALAYIVFVLTLNIVAFVIVCCCHVKIYITV---YN
PGDKDTKIAKRMAVLIFTDFICMAPISFYALSAILN---TVSNSKILLVLFYPLNSCANP
FLYAIFTKAFQRDV
>LGR4_HUMAN
LGSWMIRLTVWFIFLVALFFNLLVILTTFASCT---PSSKLFIGLISVSNLFMGIYTGIL
TFLDA---WWETGSGCKVAGFLAVFSSESAIFLLMLATVERSLSAKDIMK---NHLKQFR
VAALLAFLGATVAGCFPLFH---TPSLGFTVTLVLLNSLAFLLMAVIYTKLYCNL---DL
SENSQSSMIKHVAWLIFTNCIFFCPVAFFSFAPLIT---SPEIMKSVTLIFFPLPACLNP
VLYVFFNPKFKEDW
>LGR5_HUMAN
LDGWLIRIGVWTIAVLALTCNALVTSTVFRSPL---SPIKLLIGVIAAVNMLTGVSSAVL
AGVDA---WWENGVGCHVIGFLSIFASESSVFLLTLAALERGFSVKYSAK---APFSSLK
VIILLCALLALTMAAVPLLG---PSTMGYMVALILLNSLCFLMMTIAYTKLYCNL---DL
ENIWDCSMVKHIALLLFTNCILNCPVAFLSFSSLIN---SPEVIKFILLVVVPLPACLNP
LLYILFNPHFKEDL
>LGR6_HUMAN
FESWGIRLAVWAIVLLSVLCNGLVLLTVFAGGP---PPVKFVVGAIAGANTLTGISCGLL
ASVDA---RWETGLGCRATGFLAVLGSEASVLLLTLAAVQCSVSVSCVRA---PSLGSVR
AGVLGCLALAGLAAALPLAS---PAALGFTVALVMMNSFCFLVVAGAYIKLYCDL---DF
EAVWDCAMVRHVAWLIFADGLLYCPVAFLSFASMLG---TPEAVKSVLLVVLPLPACLNP
LLYLLFNPHFRDDL
>RXFP1_HUMAN
LASIIQRVFVWVVSAVTCFGNIFVICMRPYIRS---KLYAMSIISLCCADCLMGIYLFVI
GGFDL---LWMESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFR---PGKCRTI
TVLILIWITGFIVAFIPLSN---GAQIYSVAIFLGINLAAFIIIVFSYGSMFYSV---RN
QVKKEMILAKRFFFIVFTDALCWIPIFVVKFLSLLQ---PGTITSWVVIFILPINSALNP
ILYTLTTRPFKEMI
>RXFP2_HUMAN
LANNILRIFVWVIAFITCFGNLFVIGMRSFIKA---TTHAMSIKILCCADCLMGVYLFFV
GIFDI---LWMESVQCRLMGFLAMLSTEVSVLLLTYLTLEKFLVIVFPFS---PGKRQTS
VILICIWMAGFLIAVIPFWN---GSKGYSLGIFLGVNLLAFLIIVFSYITMFCSI---RN
CFGREVAVANRFFFIVFSDAICWIPVFVVKILSLFR---PDTMTSWIVIFFLPVNSALNP
ILYTLTTNFFKDKL
>PD2R_HUMAN
VEKGNSAVMGGVLFSTGLLGNLLALGLLARSGL---SVFYMLVCGLTVTDLLGKCLLSPV
VLAAY---PALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFF---ITLRLGA
LVAPVVSAFSLAFCALPFMG---VLGYSVLYSSLMALLVLATVLCNLGAMRNLYA---SP
QPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFK---SEEAEDLRALRFLSVISIVDP
WIFIIFRSPVFRIF
>PE2R1_HUMAN
PPSGASPALPIFSMTLGAVSNLLALALLAQAAG---TTFLLFVASLLATDLAGHVIPGAL
VLRLY---RAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLL---VSVARAR
LALAAVAAVALAVALLPLAR---QALLAGLFASLGLVALLAALVCNTLSGLALLR---RR
ARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGG---SLQRPLFLAVRLASWNQILDP
WVYILLRQAVLRQL
>PE2R2_HUMAN
LPPGESPAISSVMFSAGVLGNLIALALLARRWR---SLFHVLVTELVFTDLLGTCLISPV
VLASY---LAPESRACTYFAFAMTFFSLATMLMLFAMALERYLSIGHPYF---VSRSGGL
AVLPVIYAVSLLFCSLPLLD---RTAYLQLYATLLLLLIVSVLACNFSVILNLIR---RV
SMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETS---RKEKWDLQALRFLSINSIIDP
WVFAILRPPVLRLM
>PE2R3_HUMAN
DCGSVSVAFPITMLLTGFVGNALAMLLVSRSYR---KSFLLCIGWLALTDLVGQLLTTPV
VIVVY---IDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHW---MKTRATR
AVLLGVWLAVLAFALLPVLG---NLFFASAFAFLGLLALTVTFSCNLATIKALVS---AQ
WGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFN---KECNFFLIAVRLASLNQILDP
WVYLLLRKILLRKF
>PE2R4_HUMAN
DRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRK---TTFYTLVCGLAVTDLLGTLLVSPV
TIATY---WPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYF---VDKRLAG
LTLFAVYASNVLFCALPNMG---HAAYSYMYAGFSSFLILATVLCNVLVCGALLR---RR
IAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLY---VSKNPDLQAIRIASVNPILDP
WIYILLRKTVLSKA
>PF2R_HUMAN
TENRLSVFFSVIFMTVGILSNSLAIAILMKAYQ---ASFLLLASGLVITDFFGHLINGAI
AVFVY---FDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIF---ITSKHVK
MMLSGVCLFAVFIALLPILG---DRFYLLLFSFLGLLALGVSLLCNAITGITLLR----Q
GRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGIN---ETCETTLFALRMATWNQILDP
WVYILLRKAVLKNL
>PI2R_HUMAN
VRGSVGPATSTLMFVAGVVGNGLALGILSARRP---SAFAVLVTGLAATDLLGTSFLSPA
VFVAY---ARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYL---DGPRCAR
LALPAIYAFCVLFCALPLLG---GAAFSLAYAGLVALLVAAIFLCNGSVTLSLCR---PR
TGEDEVDHLILLALMTVVMAVCSLPLTIRCFTQAVA---SSEMGDLLAFRFYAFNPILDP
WVFILFRKAVFQRL
>TA2R_HUMAN
RRLIASPWFAASFCVVGLASNLLALSVLAGARQ---SSFLTFLCGLVLTDFLGLLVTGTI
VVSQH---VDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFS---ASQRRAW
ATVGLVWAAALALGLLPLLG---DVAFGLLFSMLGGLSVGLSFLLNTVSVATLCH---QR
PRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLR---TTEKELLIYLRVATWNQILDP
WVYILFRRAVLRRL
>MAS_HUMAN
RQIPIVHWVIMSISPVGFVENGILLWFLCFRMR---NPFTVYITHLSIADISLLFCIFIL
SIDYA---SSGHYYTIVTLSVTFLFGYNTGLYLLTAISVERCLSVLYPIW---RPKYQSA
LVCALLWALSCLVTTMEYVM---RAVIIFIAILSFLVFTPLMLVSSTILVVKIRK---NT
WASHSSKLYIVIMVTIIIFLIFAMPMRLLYLLYYEY---TFGNLHHISLLFSTINSSANP
FIYFFVGSSKKKRF
>MRGRD_HUMAN
TAYLVLSSLAMFTCLCGMAGNSMVIWLLGFRMH---NPFCIYILNLAAADLLFLFSMAST
LSLET---VNTTDKVHELMKRLMYFAYTVGLSLLTAISTQRCLSVLFPIW---RPRHLSA
WVCGLLWTLCLLMNGLTSSF---FRVDMVQAALIMGVLTPVMTLSSLTLFVWVRR---QQ
WRRQPTRLFVVVLASVLVFLICSLPLSIYWFVLYWL---MQVLCFSLSRLSSSVSSSANP
VIYFLVGSRRSHRL
>MRGRF_HUMAN
PPPAVMNYIFLLLCLCGLVGNGLVLWFFGFSIK---NPFSIYFLHLASADVGYLFSKAVF
SILNT---GTFADYIRSVCRVLGLCMFLTGVSLLPAVSAERCASVIFPAW---RPKRLSA
VVCALLWVLSLLVTCLHNYF---RHMDIFLGILLFLLCCPLMVLPCLALILHVEC---AR
RRQRSAKLNHVILAMVSVFLVSSIYLGIDWFLFWVF---PAPFPEYVTDLCICINSSAKP
IVYFLAGRDKSQRL
>MAS1L_HUMAN
LPLNIIAPKAVLVSLCGVLLNGTVFWLLCCGA----NPYMVYILHLVAADVIYLCCSAVG
FLQVT---HGVVFFIPDFLAILSPFSFEVCLCLLVAISTERCVCVLFPIW---RPKYTSN
VVCTLIWGLPFCINIVKSLF---CVIFLKLSGLFHAILSLVMCVSSLTLLIRFLC---CS
QQQKATRVYAVVQISAPMFLLWALPLSVAPLITDFK---MFVTTSYLISLFLIINSSANP
IIYFFVGSLRKKRL
>MRGRE_HUMAN
AFNLIILSLTEGLGLGGLLGNGAVLWLLSSNVY---NPFAIYLLDVACADLIFLGCHMVA
IVPDL---LDFPGFVQTSLATLRFFCYIVGLSLLAAVSVEQCLAALFPAW---RPRHLTT
CVCALTWALCLLLHLLLSGA---CRTLWLVAAVLLALLCCTMCGASLMLLLRVER---GP
QRPPPRGFPGLILLTVLLFLFCGLPFGIYWLSRNLL---IPHYFYHFSFLMAAVHCAAKP
VVYFCLGSAQGRRL
>MRGRG_HUMAN
TFDSVVFYLTLIVGLGGPVGNGLVLWNLGFRIK---GPFSIYLLHLAAADFLFLSCRVGF
SVAQ-----AALGAQDTLYFVLTFLWFAVGLWLLAAFSVERCLSDLFPAC---RPRHASA
VLCALVWTPTLPAVPLPANA---CPRYHVASVTWFLVLARVAWTAGVVLFVWVTC----C
STRPRPRLYGIVLGALLLLFFCGLPSVFYWSLQPLL---LLPVFSPLATLLACVNSSSKP
LIYSGLGRQPGKRE
>MRGX1_HUMAN
KQTLSLTVLTCIVSLVGLTGNAVVLWLLGCRMR---NAFSIYILNLAAADFLFLSGRLIY
SLLSF---ISIPHTISKILYPVMMFSYFAGLSFLSAVSTERCLSVLWPIW---RPTHLSA
VVCVLLWALSLLRSILEWML---CQTSDFITVAWLIFLCVVLCGSSLVLLIRILC---GS
RKIPLTRLYVTILLTVLVFLLCGLPFGIQFFLFLWI---LFCHVHLVSIFLSALNSSANP
IIYFFVGSFRQRQN
>MRGX2_HUMAN
KETLIPVFLILFIALVGLVGNGFVLWLLGFRMR---NAFSVYVLSLAGADFLFLCFQIIN
CLVYL---CSISINFPSFFTTVMTCAYLAGLSMLSTVSTERCLSVLWPIW---RPRHLSA
VVCVLLWALSLLLSILEGKF---CQTFDFITAAWLIFLFMVLCGSSLALLVRILC---GS
RGLPLTRLYLTILLTVLVFLLCGLPFGIQWFLILWI---LFCHIHPVSVVLSSLNSSANP
IIYFFVGSFRKQWR
>MRGX3_HUMAN
KQTLSFTGLTCIVSLVALTGNAVVLWLLGCRMR---NAVSIYILNLVAADFLFLSGHIIC
SPLRL---INIRHPISKILSPVMTFPYFIGLSMLSAISTERCLSILWPIW---RPRYLSS
VMCVLLWALSLLRSILEWMF---CETSDFITIAWLVFLCVVLCGSSLVLLVRILC---GS
RKMPLTRLYVTILLTVLVFLLCGLPFGIQWALFSRI---LFCHVHLVSIFLSALNSSANP
IIYFFVGSFRQRQN
>MRGX4_HUMAN
NQTLSFTVLTCIISLVGLTGNAVVLWLLGYRMR---NAVSIYILNLAAADFLFLSFQIIR
SPLRL---INISHLIRKILVSVMTFPYFTGLSMLSAISTERCLSVLWPIW---RPTHLSA
VVCVLLWGLSLLFSMLEWRF---CETSDFIPVAWLIFLCVVLCVSSLVLLVRILC---GS
RKMPLTRLYVTILLTVLVFLLCGLPFGILGALIYRM---LYCHVYLVCMSLSSLNSSANP
IIYFFVGSFRQRQN
>ACTHR_HUMAN
PRVVLPEEIFFTISIVGVLENLIVLLAVFKNKN---APMYFFICSLAISDMLGSLYKILE
NILII---GSFETTADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALR---VTMRRTV
VVLTVIWTFCTGTGITMVIF-----HVPTVITFTSLFPLMLVFILCLYVHMFLLA---ST
LPRANMKGAITLTILLGVFIFCWAPFVLHVLLMTFC---CYMSLFQVNGMLIMCNAVIDP
FIYAFRSPELRDAF
>MC3R_HUMAN
EQVFIKPEVFLSLGIVSLLENILVILAVVRNGN---SPMYFFLCSLAVADMLVSVSNALE
TIMIA---DQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALR---MTVRKAL
TLIVAIWVCCGVCGVVFIVY-----SKMVIVCLITMFFAMMLLMGTLYVHMFLFA---AP
QQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITC---CYTAHFNTYLVLIMCNSVIDP
LIYAFRSLELRNTF
>MC4R_HUMAN
EQLFVSPEVFVTLGVISLLENILVIVAIAKNKN---SPMYFFICSLAVADMLVSVSNGSE
TIIIT---QSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQ---MTVKRVG
IIISCIWAACTVSGILFIIY-----SSAVIICLITMFFTMLALMASLYVHMFLMA---AI
RQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISC---CFMSHFNLYLILIMCNSIIDP
LIYALRSQELRKTF
>MC5R_HUMAN
EDMGIAVEVFLTLGVISLLENILVIGAIVKNKN---SPMYFFVCSLAVADMLVSMSSAWE
TITIY---DAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALR---MTARRSG
AIIAGIWAFCTGCGIVFILY-----STYVILCLISMFFAMLFLLVSLYIHMFLLA---SA
RQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSC---RFMSHFNMYLILIMCNSVMDP
LIYAFRSQEMRKTF
>MSHR_HUMAN
LEVSISDGLFLSLGLVSLVENALVVATIAKNRN---SPMYCFICCLALSDLLVSGSNVLE
TAVIL---AAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALR---VTLPRAR
RAVAAIWVASVVFSTLFIAY-----HVAVLLCLVVFFLAMLVLMAVLYVHMLARA---PV
HQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLC---CIFKNFNLFLALIICNAIIDP
LIYAFHSQELRRTL
>GP119_HUMAN
ESSFSFGVILAVLASLIIATNTLVAVAVLLLIH---GVSLCFTLNLAVADTLIGVAISGL
LTDQL---RPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFR---MSGFVAG
ACIAGLWLVSYLIGFLPLGI---FHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIA---SP
RTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVAC---LYLVLERYLWLLGVGNSLLNP
LIYAYWQKEVRLQL
>GPR12_HUMAN
LVVNPWDIVLCTSGTLISCENAIVVLIIFHNPS---APMFLLIGSLALADLLAGIGLITN
FVFAY---LLQSEATKLVTIGLIVASFSASVCSLLAITVDRYLSLYYALT---RTVTFTY
VMLVMLWGTSICLGLLPVMG---PLTKNNAAILSVSFLFMFALMLQLYIQICKIV---TS
HYVTTRKGVSTLAIILGTFAACWMPFTLYSLIADYT----PSIYTYATLLPATYNSIINP
VIYAFRNQEIQKAL
>GPR3_HUMAN
PSPKAWDVVLCISGTLVSCENALVVAIIVGTPA---APMFLLVGSLAVADLLAGLGLVLH
FAAVF---CIGSAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALT---TTVTRTY
VMLALVWGGALGLGLLPVLA---PLSKNHLVVLAIAFFMVFGIMLQLYAQICRIV---AS
HYVATRKGIATLAVVLGAFAACWLPFTVYCLLGDAH----PPLYTYLTLLPATYNSMINP
IIYAFRNQDVQKVL
>GPR6_HUMAN
PAVNPWDVLLCVSGTVIAGENALVVALIASTPA---TPMFVLVGSLATADLLAGCGLILH
FVFQY---LVPSETVSLLTVGFLVASFAASVSSLLAITVDRYLSLYNALT---RTLLGVH
LLLAATWTVSLGLGLLPVLG---PLARSHVALLSAAFFMVFGIMLHLYVRICQVV---PP
HLAATRKGVGTLAVVLGTFGASWLPFAIYCVVGSHE----PAVYTYATLLPATYNSMINP
IIYAFRNQEIQRAL
>S1PR1_HUMAN
NSIKLTSVVFILICCFIILENIFVLLTIWKTKK---RPMYYFIGNLALSDLLAGVAYTAN
LLLSG---YKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKL---SNNFRLF
LLISACWVISLILGGLPIMG---LYHKHYILFCTTVFTLLLLSIVILYCRIYSLV---SR
SSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGC---DILFRAEYFLVLAVLNSGTNP
IIYTLTNKEMRRAF
>S1PR2_HUMAN
TSRQVASAFIVILCCAIVVENLLVLIAVARNSK---SAMYLFLGNLAASDLLAGVAFVAN
TLLSG---LRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKL---DKSCRML
LLIGASWLISLVLGGLPILG---LYAKHYVLCVVTIFSIILLAIVALYVRIYCVV---DM
AAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYAC---PILYKAHYFFAVSTLNSLLNP
VIYTWRSRDLRREV
>S1PR3_HUMAN
EGSTLTTVLFLVICSFIVLENLMVLIAIWKNNK---NRMYFFIGNLALCDLLAGIAYKVN
ILMSG---FSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRP---NKRHRVF
LLIGMCWLIAFTLGALPILG---LYSKKYIAFCISIFTAILVTIVILYARIYFLV---HN
NSERSMALLRTVVIVVSVFIACWSPLFILFLIDVAC---PILFKAQWFIVLAVLNSAMNP
VIYTLASKEMRRAF
>S1PR4_HUMAN
GGLGALRGLSVAASCLVVLENLLVLAAITSHMR---RWVYYCLVNITLSDLLTGAAYLAN
VLLSG---FRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVA---TKTSRVY
GFIGLCWLLAALLGMLPLLG---LYSKRYILFCLVIFAGVLATIMGLYGAIFRLV---PA
ARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFG---EYLRGMDWILALAVLNSAVNP
IIYSFRSREVCRAV
>S1PR5_HUMAN
AGLRADAVVCLAVCAFIVLENLAVLLVLGRHPR---APMFLLLGSLTLSDLLAGAAYAAN
ILLSG---LKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGP---SSRGRTL
AMAAAAWGVSLLLGLLPALG---LYAKAYVLFCVLAFVGILAAICALYARIYCQV---AR
RKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVAC---PVLLQADPFLGLAMANSLLNP
IIYTLTNRDLRHAL
>CNR1_HUMAN
SQQLAIAVLSLTLGTFTVLENLLVLCVILHSRS---RPSYHFIGSLAVADLLGSVIFVYS
FIDFH---RKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLA---VTRPKAV
VAFCLMWTIAIVIAVLPLLG---HIDETYLMFWIGVTSVLLLFIVYAYMYILWKA---PD
QARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFG---LIKTVFAFCSMLCLLNSTVNP
IIYALRSKDLRHAF
>CNR2_HUMAN
PQKTAVAVLCTLLGLLSALENVAVLYLILSSHQ---KPSYLFIGSLAGADFLASVVFACS
FVNFH---GVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPS---LTRGRAL
VTLGIMWVLSALVSYLPLMG---LIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKA---MA
RMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLAT---QVKKAFAFCSMLCLINSMVNP
VIYALRSGEIRSSA
>LPAR1_HUMAN
TVSKLVMGLGITVCIFIMLANLLVMVAIYVNRR---FPIYYLMANLAAADFFAGLAYFYL
MFNTG---RRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQL---MSNRRVV
VVIVVIWTMAIVMGAIPSVG---LYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYV---RR
NRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCC---DVLAYEKFFLLLAEFNSAMNP
IIYSYRDKEMSATF
>LPAR2_HUMAN
PKDVVVVALGLTVSVLVLLTNLLVIAAIASNRR---QPIYYLLGNLAAADLFAGVAYLFL
MFHTG---ARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQL---LPRGRVV
MLIVGVWVAALGLGLLPAHS---LLSRSYLAVWALSSLLVFLLMVAVYTRIFFYV---PR
YRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLG---NVLAVEKYFLLLAEANSLVNA
AVYSCRDAEMRRTF
>LPAR3_HUMAN
TKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRK---FPFYYLLANLAAADFFAGIAYVFL
MFNTG---KTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRV---LTKKRVT
LLILLVWAIAIFMGAVPTLG---IYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYV---IS
RRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLN---GVQHVKRWFLLLALLNSVVNP
IIYSYKDEDMYGTM
>AA1R_HUMAN
AFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQA---DATFCFIVSLAVADVAVGALVIPL
AILIN---PQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLR---VTPRRAA
VAIAGCWILSFVVGLTPMFG---SMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLI---QK
YYGKELKIAKSLALILFLFALSWLPLHILNCITLFC---KPSILTYIAIFLTHGNSAMNP
IVYAFRIQKFRVTF
>AA2AR_HUMAN
MGSSVYITVELAIAVLAILGNVLVCWAVWLNSN---NVTNYFVVSLAAADIAVGVLAIPF
AITIS---FCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLR---VTGTRAK
GIIAICWVLSFAIGLTPMLG---PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAA---RS
TLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFC---APLWLMYLAIVLSHTNSVVNP
FIYAYRIREFRQTF
>AA2BR_HUMAN
TQDALYVALELVIAALSVAGNVLVCAAVGTANT---TPTNYFLVSLAAADVAVGLFAIPF
AITIS---FCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLR---VTGTRAR
GVIAVLWVLAFGIGLTPFLG---PMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVA---RT
TLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQ---KPKWAMNMAILLSHANSVVNP
IVYAYRNRDFRYTF
>AA3R_HUMAN
LANVTYITMEIFIGLCAIVGNVLVICVVKLNPS---TTTFYFIVSLALADIAVGVLVMPL
AIVVS---ITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVR---TTHRRIW
LALGLCWLVSFLVGLTPMFG---RMDYMVYFSFLTWIFIPLVVMCAIYLDIFYII---GA
FYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFN---VPQLVLYMGILLSHANSMMNP
IVYAYKIKKFKETY
>5HT1A_HUMAN
SYQVITSLLLGTLIFCAVLGNACVVAAIALERS---NVANYLIGSLAVTDLMVSVLVLPM
AALYQ---WTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPID---RTPRRAA
ALISLTWLIGFLISIPPMLG---KDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAA---KM
ALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFC---MPTLLGAIINWLGYSNSLLNP
VIYAYFNKDFQNAF
>5HT1B_HUMAN
PWKVLLVMLLALITLATTLSNAFVIATVYRTRK---TPANYLIASLAVTDLLVSILVMPI
STMYT---WTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVE---RTPKRAA
VMIALVWVFSISISLPPFFW---DHILYTVYSTVGAFYFPTLLLIALYGRIYVEA---KL
MAARERKATKTLGIILGAFIVCWLPFFIISLVMPIC---FHLAIFDFFTWLGYLNSLINP
IIYTMSNEDFKQAF
>5HT1D_HUMAN
ALKISLAVVLSVITLATVLSNAFVLTTILLTRK---TPANYLIGSLATTDLLVSILVMPI
SIAYT---WNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALE---RTAGHAA
TMIAIVWAISICISIPPLFW---SQISYTIYSTCGAFYIPSVLLIILYGRIYRAA---RI
SAARERKATKILGIILGAFIICWLPFFVVSLVLPIC---IHPALFDFFTWLGYLNSLINP
IIYTVFNEEFRQAF
>5HT1E_HUMAN
TEKMLICMTLVVITTLTTLLNLAVIMAIGTTKK---QPANYLICSLAVTDLLVAVLVMPL
SIIYI---WKLGYFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIE---RTAKRAA
LMILTVWTISIFISMPPLFW---DHVIYTIYSTLGAFYIPLTLILILYYRIYHAA---QI
SSTRERKAARILGLILGAFILSWLPFFIKELIVGLS---VSSEVADFLTWLGYVNSLINP
LLYTSFNEDFKLAF
>5HT1F_HUMAN
PSKILVSLTLSGLALMTTTINSLVIAAIIVTRK---HPANYLICSLAVTDFLVAVLVMPF
SIVYI---WIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVE---RTPKHAG
IMITIVWIISVFISMPPLFW---DHIVSTIYSTFGAFYIPLALILILYYKIYRAA---KI
SGTRERKAATTLGLILGAFVICWLPFFVKELVVNVC---ISEEMSNFLAWLGYLNSLINP
LIYTIFNEDFKKAF
>5HT2A_HUMAN
QEKNWSALLTAVVIILTIAGNILVIMAVSLEKK---NATNYFLMSLAIADMLLGFLVMPV
SMLTI---WPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIH---NSRTKAF
LKIIAVWTISVGISMPIPVF---ADDNFVLIGSFVSFFIPLTIMVITYFLTIKSL---MQ
SISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVIC---VIGALLNVFVWIGYLSSAVNP
LVYTLFNKTYRSAF
>5HT2B_HUMAN
NKLHWAALLILMVIIPTIGGNTLVILAVSLEKK---YATNYFLMSLAVADLLVGLFVMPI
ALLTI---WPLPLVLCPAWLFLDVLFSTASIMHLCAISVDRYIAIKKPIQ---NSRATAF
IKITVVWLISIGIAIPVPIK---RFGDFMLFGSLAAFFTPLAIMIVTYFLTIHAL---VQ
TISNEQRASKVLGIVFFLFLLMWCPFFITNITLVLC---TLQMLLEIFVWIGYVSSGVNP
LVYTLFNKTFRDAF
>5HT2C_HUMAN
GVQNWPALSIVIIIIMTIGGNILVIMAVSMEKK---NATNYFLMSLAIADMLVGLLVMPL
SLLAI---WPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIE---NSRTKAI
MKIAIVWAISIGVSVPIPVI---NDPNFVLIGSFVAFFIPLTIMVITYCLTIYVL---MQ
AINNERKASKVLGIVFFVFLIMWCPFFITNILSVLC---LMEKLLNVFVWIGYVCSGINP
LVYTLFNKIYRRAF
>5HT4R_HUMAN
VEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQ---IKTNYFIVSLAFADLLVSVLVMPF
GAIEL---WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPL---MTPLRIA
LMLGGCWVIPTFISFLPIMQ---NK-PYAITCSVVAFYIPFLLMVLAYYRIYVTA---TH
RMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI---VPGQVWTAFLWLGYINSGLNP
FLYAFLNKSFRRAF
>5HT5A_HUMAN
VFGVLILTLLGFLVAATFAWNLLVLATILRVRT---RVPHNLVASMAVSDVLVAALVMPL
SLVHE---WQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHME---TRKCVSN
VMIALTWALSAVISLAPLLF---REPSYAVFSTVGAFYLPLCVVLFVYWKIYKAA---TW
REQKEQRAALMVGILIGVFVLCWIPFFLTELISPLC---IPAIWKSIFLWLGYSNSFFNP
LIYTAFNKNYNSAF
>5HT6R_HUMAN
GGSGWVAAALCVVIALTAAANSLLIALICTQPA---NTSNFFLVSLFTSDLMVGLVVMPP
AMLNA---WVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLR---MTPLRAL
ALVLGAWSLAALASFLPLLL---ASLPFVLVASGLTFFLPSGAICFTYCRILLAA---TK
HSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVC---ISPGLFDVLTWLGYCNSTMNP
IIYPLFMRDFKRAL
>5HT7R_HUMAN
VEKVVIGSILTLITLLTIAGNCLVVISVCFVKK---QPSNYLIVSLALADLSVAVAVMPF
VSVTD---WIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLT---QNGKCMA
KMILSVWLLSASITLPPLFG---QDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAA---IS
IFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFI---IPLWVERTFLWLGYANSLINP
FIYAFFNRDLRTTY
>ACM1_HUMAN
WQVAFIGITTGLLSLATVTGNLLVLISFKVNTE---TVNNYFLLSLACADLIIGTFSMNL
YTTYL---WALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLS---RTPRRAA
LMIGLAWLVSFVLWAPAILF---SQPIITFGTAMAAFYLPVTVMCTLYWRIYRET---TF
SLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFC---VPETLWELGYWLCYVNSTINP
MCYALCNKAFRDTF
>ACM2_HUMAN
FEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRH---TVNNYFLFSLACADLIIGVFSMNL
YTLYT---WPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLT---RTTKMAG
MMIAAAWVLSFILWAPAILF---SNAAVTFGTAIAAFYLPVIIMTVLYWHISRAS---KP
PPSREKKVTRTILAILLAFIITWAPYNVMVLINTFC---IPNTVWTIGYWLCYINSTINP
ACYALCNATFKKTF
>ACM3_HUMAN
WQVVFIAFLTGILALVTIIGNILVIVSFKVNKQ---TVNNYFLLSLACADLIIGVISMNL
FTTYI---WALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLT---RTTKRAG
VMIGLAWVISFVLWAPAILF---SEPTITFGTAIAAFYMPVTIMTILYWRIYKET---RM
SLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFC---IPKTFWNLGYWLCYINSTVNP
VCYALCNKTFRTTF
>ACM4_HUMAN
VEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQ---TVNNYFLFSLACADLIIGAFSMNL
YTVYI---WPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLT---RTTKMAG
LMIAAAWVLSFVLWAPAILF---SNPAVTFGTAIAAFYLPVVIMTVLYIHISLAS---RQ
MAARERKVTRTIFAILLAFILTWTPYNVMVLVNTFC---IPDTVWSIGYWLCYVNSTINP
ACYALCNATFKKTF
>ACM5_HUMAN
WEVITIAAVTAVVSLITIVGNVLVMISFKVNSQ---TVNNYYLLSLACADLIIGIFSMNL
YTTYI---WALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLT---RTPKRAG
IMIGLAWLISFILWAPAILC---SEPTITFGTAIAAFYIPVSVMTILYCRIYRET---RV
VLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFC---VPVTLWHLGYWLCYVNSTVNP
ICYALCNRTFRKTF
>ADA1A_HUMAN
SKAILLGVILGGLILFGVLGNILVILSVACHRH---SVTHYYIVNLAVADLLLTSTVLPF
SAIFE---WAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLR---VTQRRGL
MALLCVWALSLVISIGPLFG---EEPGYVLFSALGSFYLPLAIILVMYCRVYVVA---LL
KFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFF---PSETVFKIVFWLGYLNSCINP
IIYPCSSQEFKKAF
>ADA1B_HUMAN
TRAISVGLVLGAFILFAIVGNILVILSVACNRH---TPTNYFIVNLAMADLLLSFTVLPF
SAALE---WVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQ---VTRRKAI
LALLSVWVLSTVISIGPLLG---EEPFYALFSSLGSFYIPLAVILVMYCRVYIVA---LF
KFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLF---PPDAVFKVVFWLGYFNSCLNP
IIYPCSSKEFKRAF
>ADA1D_HUMAN
AQGVGVGVFLAAFILMAVAGNLLVILSVACNRH---TVTNYFIVNLAVADLLLSATVLPF
SATME---WAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLK---MTERKAA
AILALLWVVALVVSVGPLLG---EEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVA---LL
KFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLF---PSEGVFKVIFWLGYFNSCVNP
LIYPCSSREFKRAF
>ADA2A_HUMAN
QVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRA---APQNLFLVSLASADILVATLVIPF
SLANE---WYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIE---RTPRRIK
AIIITVWVISAVISFPPLIS---DQKWYVISSCIGSFFAPCLIMILVYVRIYQIA---RG
RQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVG---VPRTLFKFFFWFGYCNSSLNP
VIYTIFNHDFRRAF
>ADA2B_HUMAN
QATAAIAAAITFLILFTIFGNALVILAVLTSRS---APQNLFLVSLAAADILVATLIIPF
SLANE---WYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALE---RTPRRIK
CIILTVWLIAAVISLPPLIY---QEAWYILASSIGSFFAPCLIMILVYLRIYLIA---RA
QLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAIC---VPHGLFQFFFWIGYCNSSLNP
VIYTIFNQDFRRAF
>ADA2C_HUMAN
GAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRA---APQNLFLVSLASADILVATLVMPF
SLANE---WYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVE---RTPRRVK
ATIVAVWLISAVISFPPLVS---DETWYILSSCIGSFFAPCLIMGLVYARIYRVA---KV
AQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGIC---VPGPLFKFFFWIGYCNSSLNP
VIYTVFNQDFRRSF
>ADRB1_HUMAN
QWTAGMGLLMALIVLLIVAGNVLVIVAIAKTPR---TLTNLFIMSLASADLVMGLLVVPF
GATIV---WEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFR---LTRARAR
GLVCTVWAISALVSFLPILM---TNRAYAIASSVVSFYVPLCIMAFVYLRVFREA---RL
VALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFH---VPDRLFVFFNWLGYANSAFNP
IIYCRSPDFRKAFQ
>ADRB2_HUMAN
VWVVGMGIVMSLIVLAIVFGNVLVITAIAKFER---TVTNYFITSLACADLVMGLAVVPF
GAAHI---WTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFK---LTKNKAR
VIILMVWIVSGLTSFLPIQM---TNQAYAIASSIVSFYVPLVIMVFVYSRVFQEA---SK
FCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQ---IRKEVYILLNWIGYVNSGFNP
LIYCRSPDFRIAFQ
>ADRB3_HUMAN
WEAALAGALLALAVLATVGGNLLVIVAIAWTPR---TMTNVFVTSLAAADLVMGLLVVPP
AATLA---WPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLR---VTKRCAR
TAVVLVWVVSAAVSFAPIMS---SNMPYVLLSSSVSFYLPLLVMLFVYARVFVVA---RL
LPLREHRALCTLGLIMGTFTLCWLPFFLANVLRALG---VPGPAFLALNWLGYANSAFNP
LIYCRSPDFRSAFR
>DRD1_HUMAN
SVRILTACFLSLLILSTLLGNTLVCAAVIRFRH---KVTNFFVISLAVSDLLVAVLVMPW
KAVAE---FWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFR---MTPKAAF
ILISVAWTLSVLISFIPVQL---LSRTYAISSSVISFYIPVAIMIVTYTRIYRIA---KM
SFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFC---IDSNTFDVFVWFGWANSSLNP
IIYAFNADFRKAFS
>DRD2_HUMAN
PHYNYYATLLTLLIAVIVFGNVLVCMAVSREKA---TTTNYLIVSLAVADLLVATLVMPW
VVYLE---WKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPML---SSKRRVT
VMISIVWVLSFTISCPLLFG---ANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVL---KL
SQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHC---IPPVLYSAFTWLGYVNSAVNP
IIYTTFNIEFRKAF
>DRD3_HUMAN
RPHAYYALSYCALILAIVFGNGLVCMAVLKERA---TTTNYLVVSLAVADLLVATLVMPW
VVYLE---WNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVH---SSCRRVA
LMITAVWVLAFAVSCPLLFG---SNPDFVIYSSVVSFYLPFGVTVLVYARIYVVL---RG
VPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHC---VSPELYSATTWLGYVNSALNP
VIYTTFNIEFRKAF
>DRD4_HUMAN
GQGAAALVGGVLLIGAVLAGNSLVCVSVATERA---TPTNSFIVSLAAADLLLALLVLPL
FVYSE---WLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLR---GGSRRQL
LLIGATWLLSAAVAAPVLCG---EDRDYVVYSSVCSFFLPCPLMLLLYWATFRGL---AK
ITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALC---VPPRLVSAVTWLGYVNSALNP
VIYTVFNAEFRNVF
>DRD5_HUMAN
PSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRH---NMTNVFIVSLAVSDLFVALLVMPW
KAVAE---YWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFR---MTQRMAL
VMVGLAWTLSILISFIPVQL---LNRTYAISSSLISFYIPVAIMIVTYTRIYRIA---RA
SIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFC---VSETTFDVFVWFGWANSSLNP
VIYAFNADFQKVFA
>HRH1_HUMAN
PQLMPLVVVLSTICLVTVGLNLLVLYAVRSERK---TVGNLYIVSLSVADLIVGAVVMPM
NILYL---WSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLR---RTKTRAS
ATILGAWFLSFLWVIPILGW---DVTWFKVMTAIINFYLPTLLMLWFYAKIYKAV---GL
HMNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFC---CNEHLHMFTIWLGYINSTLNP
LIYPLCNENFKKTF
>HRH2_HUMAN
ACKITITVVLAVLILITVAGNVVVCLAVGLNRR---NLTNCFIVSLAITDLLLGLLVLPF
SAIYQ---WSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLR---VTPVRVA
ISLVLIWVISITLSFLSIHL---VNEVYGLVDGLVTFYLPLLIMCITYYRIFKVA---KA
ATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLR---INEVLEAIVLWLGYANSALNP
ILYAALNRDFRTGY
>HRH3_HUMAN
AWTAVLAALMALLIVATVLGNALVMLAFVADSS---TQNNFFLLNLAISDFLVGAFCIPL
YVPYV---WTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVS---GDTRRAV
RKMLLVWVLAFLLYGPAILS---YNWYFLITASTLEFFTPFLSVTFFNLSIYLNI---RF
RLSRDRKVAKSLAVIVSIFGLCWAPYTLLMIIRAAC---VPDYWYETSFWLLWANSAVNP
VLYPLCHHSFRRAF
>HRH4_HUMAN
STRVTLAFFMSLVAFAIMLGNALVILAFVVDKN---HRSSYFFLNLAISDFFVGVISIPL
YIPHT---WDFGKEICVFWLTTDYLLCTASVYNIVLISYDRYLSVSNAVS---TGVLKIV
TLMVAVWVLAFLVNGPMILV---SEWYILAITSFLEFVIPVILVAYFNMNIYWSL---HV
ELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFY---PKSVWYRIAFWLQWFNSFVNP
LLYPLCHKRFQKAF
>TAAR1_HUMAN
DVRASLYSLMVLIILTTLVGNLIVIVSISHFKQ---TPTNWLIHSMATVDFLLGCLVMPY
SMVRS---WYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLR---MNILVIC
VMIFISWSVPAVFAFGMIFL---FSKISGVLTFMTSFYIPGSIMLCVYYRIYLIA---GI
SQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFL---IPPTLNDVLIWFGYLNSTFNP
MVYAFFYPWFRKAL
>TAAR2_HUMAN
GVRVAMYSFMAGSIFITIFGNLAMIISISYFKQ---TPTNFLILSMAITDFLLGFTIMPY
SMIRS---WYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLL---ITIPVIK
RLLLLCWSVPGAFAFGVVFS---FNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVS---NN
QVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFL---TPVVLFDALTWFGYFNSTCNP
LIYGFFYPWFRRAL
>TAAR3_HUMAN
SCPGDNVFGYDWSHDYPLFGNLVIMVSISHFKQ---SPTNFLILSMATTDFLLGFVIMPY
SIMRS---WYFGDGFCKFHTSFDMMLRLTSIFHLCSIAIDRFYAVCYPLH---MTNSTIK
QLLAFCWSVPALFSFGLVLS---FNKFWGTILFTTCFFTPGSIMVGIYGKIFIVS---HL
SKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYL---TPILILDLLVWLRYFNSTCNP
LIHGFFNPWFQKAF
>TAAR5_HUMAN
GIQLVIYLTCAAGMLIIVLGNVFVAFAVSYFKA---TPTNFLLLSLALADMFLGLLVLPL
STIRS---WFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLL---FTVRVAL
RYILAGWGVPAAYTSLFLYT---LLNKFWGWLNFPLFFVPCLIMISLYVKIFVVA---AG
AAKHERKAAKTLGIVVGIYLLCWLPFTIDTMVDSLL---TPPLVFDIFIWFAYFNSACNP
IIYVFSYQWFRKAL
>TAAR6_HUMAN
GSRVILYIVFGFGAVLAVFGNLLVMISILHFKQ---SPTNFLVASLACADFLVGVTVMPF
SMVRT---WYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLV---FTVSVSG
ICISVSWILPLMYSGAVFYT---VVNQNWVLTDFLSFFIPTFIMIILYGNIFLVA---AR
VARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFM---TPACIYEICCWCAYYNSAMNP
LIYALFYPWFRKAI
>TAAR8_HUMAN
GSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQ---SPTNFLIASLACADFLVGVTVMLF
SMVRT---WYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLV---FTVSVSG
ICISVSWILPLTYSGAVFYT---IVSQGWVLIDFLLFFIPTLVMIILYSKIFLIA---IR
VAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFM---TPAYIYEICCWSAYYNSAMNP
LIYALFYPWFRKAI
>TAAR9_HUMAN
GPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQ---TPTNFLIASLACADFLVGVTVMPF
STVRS---WYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLT---FTVSVSG
ICIVLSWFFSVTYSFSIFYT---PLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVA---ER
VAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYM---TPPYVYEILVWCVYYNSAMNP
LIYAFFYQWFGKAI
>GP120_HUMAN
VLAAVETTVLVLIFAVSLLGNVCALVLVARRRR---GATACLVLNLFCADLLFISAIPLV
LAVRW---WLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQR---PGRRARA
VLLALIWGYSAVAALPLCVF---GEISWDVSFVTLNFLVPGLVIVISYSKILQTS---IR
VSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQ---IWPSLFFWVVAFTFANSALNP
ILYNMTLCRNEWKK
>GP139_HUMAN
GLGFVPVVYYSLLLCLGLPANILTVIILSQLVA---KSSYNYLLALAAADILVLFFIVFV
DFLLE---MQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLK---SYPARTR
KVIVSVYITCFLTSIPYYWW---VHHVLIWIHCFTVYLVPCSIFFILNSIIVYKL---RL
RGYSTGKTTAILFTITSIFATLWAPRIIMILYHLYG---LVHIMSDIANMLALLNTAINF
FLYCFISKRFRTMA
>GP142_HUMAN
VAGVIPVIYYSVLLGLGLPVSLLTAVALARLAT---RPSYYYLLALTASDIIIQVVIVFA
GFLLQ---RQVPQAVVRTANILEFAANHASVWIAILLTVDRYTALCHPLH---SSPGRTR
RAIAAVLSAALLTGIPFYWW---LDEVLKWAHCLTVYFIPCGVFLVTNSAIIHRL---SG
LQPRVGKSTAILLGITTLFTLLWAPRVFVMLYHMYV---RVHLALDVANMVAMLHTAANF
GLYCFVSKTFRATV
>GP146_HUMAN
GLSLLSLLGLVVGVPVGLCYNALLVLANLHSKA---TMPDVYFVNMAVAGLVLSALAPVH
LLGPP---WSVGGEVHVALQIPFNVSSLVAMYSTALLSLDHYIERALPRT---ASVYNTR
HVCGFVWGGALLTSFSSLLF---NAEAADATLVFIGYVVPALATLYALVLLSRVR---RD
TGRLEPSAHRLLVATVCTQFGLWTPHYLILLGHTVI---LLHFVKDFSKLLAFSSSFVTP
LLYRYMNQSFPSKL
>GP148_HUMAN
SMLYWLFLPSSLLAAATLAVSPLLLVTILRNQR---EPHYLLPANILLSDLAYILLHMLI
SSSSL---WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLR---MSHGAAW
KAVALIWLVACCFPTFLIWL---LVIVTYTSILCVLFLCTALIANCFWRIYAEAK---SG
IWGQGYSRARGTLLIHSVLITLYVSTGVVFSLDMVL---HTWLLAANSEVLMMLPRAMLP
YLYLLRYRQLLGMV
>GP150_HUMAN
PSRRVRLVFLGVILVVAVAGNTTVLCRLCGGGG---RKMDFLLVQLALADLYACGGTALS
QLAWE---AATGDLACRFLQLLQASGRGASAHLVVLIALERRRAVRLPHG---RALAALG
WLLALLLALPPAFVVRGDSP---HLQVYAFYEAVAGFVAPVTVLGVACGHLLSVW---SA
LPRAKVQSLKMSLLLALLFVGCELPYFAARLAAAWS---EGEGLSAALRVVAMANSALNP
FVYLFFQAGDCRLR
>GP160_HUMAN
NQPLDVNYLLFLIILGKILLNILTLGMRRKNTC---NFMEYFCISLAFVDLLLLVNISII
LYFRD---RFTKYHICLFTQIISFTYGFLHYPVFLTACIDYCLNFSKTTK---CQKLFYF
FTVILIWISVLAYVLGDPAI---WLSFFMVMILFVAFITCWEEVTTLVQAIRITS---SH
SSYTVRSKKIFLSKLIVCFLSTWLPFVLLQVIIVLL---IPAYIEMNIPWLYFVNSFLIA
TVYWFNCHKLNLKD
>GP161_HUMAN
GVIITQFIAIIVITIFVCLGNLVIVVTLYKKSY---TLSNKFVFSLTLSNFLLSVLVLPF
VVTSS---WIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMV---ITGNRAV
MALVYIWLHSLIGCLPPLFG---REPGYTAFWQIWCALFPFLVMLVCYGFIFRVA---RE
PFVQRQRTSRLFSISNRITDLGLSPHLTALMAGGQP---CSQDSGTDMMLLEDYTSDDNP
PSHCTCPPKRRSSV
>GPBAR_HUMAN
PIPKGALGLSLALASLIITANLLLALGIAWDRR---PPAGCFFLSLLLAGLLTGLALPTL
PGLWN---SRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPL----QPPGSIR
LALLLTWAGPLLFASLPALG---IFPAPYLYLEVYGLLLPAVGAAAFLSVRVLAT---AL
ARALTWRQARAQAGAMLLFGLCWGPYVATLLLSVLA---LGPGTLLSLLSLGSASAAAVP
VAMGLGDQRYTAPW
>GPR21_HUMAN
NFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPL---HTTSYFIQTMAYADLFVGVSCVVP
SLSLL---PVEESLTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPLT---VTPWRLR
LCIFLIWLYSTLVFLPSFFH---TDSYFTLFIVMMLYAPAALIVCFTYFNIFRIC---EV
QACPDKRYAMVLFRITSVFYILWLPYIIYFLLESST---SNRFASFLTTWLAISNSFCNC
VIYSLSNSVFQRGL
>GPR22_HUMAN
SFQVSLTGFLMLEIVLGLGSNLTVLVLYCMKSN---SVSNIITMNLHVLDVIICVGCIPL
TIVIL---ESNTALICCFHEACVSFASVSTAINVFAITLDRYDISVKPAN---LTMGRAV
MLMISIWIFSFFSFLIPFIE---LGMYYHLLVQIPIFFFTVVVMLITYTKILQAL---RE
RRERQKRVFRMSLLIISTFLLCWTPISVLNTTILCL---LLVKLRLCFLVMAYGTTIFHP
LLYAFTRQKFQKVL
>GPR26_HUMAN
SWDAGLAGLLVGTMGVSLLSNALVLLCLLHSAD---QAPALFTLNLTCGNLLCTVVNMPL
TLAGV---QPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLS---MRLRDAA
LMVAYTWLHALTFPAAALAL---RFAVFTGAFHALSFLLSFVVLCCTYLKVLKVA---EE
QKRRRQRATKKISTFIGTFLVCFAPYVITRLVELFS---IGSHWGVLSKCLAYSKAASDP
FVYSLLRHQYRKSC
>GPR45_HUMAN
PLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPA---SAINLLLATLAFSDIMLSLCCMPF
TAVTL---WHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQD---LNPRRAK
VIIAVSWVLSFCIAGPSLTG---ADRAYVVTLVVAVFFAPFGVMLCAYMCILNTV---SV
DLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFS---SFYATSTCVLWFSYLKSVFNP
IVYCWRIKKFREAC
>GPR52_HUMAN
DVCIFETVVIVLLTFLIIAGNLTVIFAFHCAPL---YTTSYFIQTMAYADLFVGVSCLVP
TLSLL---GVHESLTCRVFGYIISVLKSVSMACLACISVDRYLAITKPLS---VTPCRLR
ICIILIWIYSCLIFLPSFFG---TSAYFTGFIVCLLYAPAAFVVCFTYFHIFKIC---ET
GHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSR---DNPTLSFLTTWLAVSNSFCNC
VIYSLSNGVFRLGL
>GPR61_HUMAN
ASESVALFFMLLLDLTAVAGNAAVMAVIAKTPA---LRKFVFVFHLCLVDLLAALTLMPL
AMLSS---ALFGEVACRLYLFLSVCFVSLAILSVSAINVERYYYVVHPMR---MTLGLVA
SVLVGVWVKALAMASVPVLG---YCQLFVVVFAVLYFLLPLLLILVVYCSMFRVA---PH
RTFGGGKAAVVLLAVGGQFLLCWLPYFSFHLYVALS---STGQVESVVTWIGYFCFTSNP
FFYGCLNRQIRGEL
>GPR62_HUMAN
VAGSLGLILAAVVEVGALLGNGALLVVVLRTPG---LRDALYLAHLCVVDLLAAASIMPL
GLLAA---VRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLR---GSRPPPV
LVLTAVWAAAGLLGALSLLG---GLGPFRPLWALLAFALPALLLLGAYGGIFVVA---LR
PRLPGGKAALAPALAVGQFAACWLPYGCACLAPAAR----AAEAEAAVTWVAYSAFAAHP
FLYGLLQRPVRLAL
>GPR63_HUMAN
PLQITLSAIMIFILFVSFLGNLVVCLMVYQKAA---SAINILLASLAFADMLLAVLNMPF
ALVTI---WIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQRQD---LNPYRAK
VLIAVSWATSFCVAFPLAVG---GYQAYVILISLISFFIPFLVILYSFMGILNTL---SI
DMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFS---NFFEISTWLLWLCYLKSALNP
LIYYWRIKKFHDAC
>GPR75_HUMAN
ATLVTCTFLLAVIFCLGSYGNFIVFLSFFDPAF---TNFDFMILNLSFCDLFICGVTAPM
FTFVL---SSIPDAFCFTFHLTSSGFIIMSLKTVAVIALHRLRMVLGKQP---ASFPCTV
LLTLLLWATSFTLATLATLK---VRKCPPVITVDASRPQPFMGVPVQGGGDPIQC---NL
STAKDSKAVVTCVIIVLSVLVCCLPLGISLVQVVLS---ILYQFELFGFTLIFFKSGLNP
FIYSRNSAGLRRKV
>GPR78_HUMAN
PGEALLAGLLVMVLAVALLSNALVLLCCAYSAE---RASGVLLVNLSLGHLLLAALDMPF
TLLGV---TPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLR---LRPRYAG
LLLGCAWGQSLAFSGAALGC---RFAAFTATLHAVGFVLPLAVLCLTSLQVHRVA---IQ
QKRRRHRATRKIGIAIATFLICFAPYVMTRLAELVP---VNAQWGILSKCLTYSKAVADP
FTYSLLRRPFRQVL
>GPR88_HUMAN
GRRIPVSLLYSGLAIGGTLANGMVIYLVSSFRK---TTSNAFIVNGCAADLSVCALWMPQ
EAVLG---DGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPA---YQRRHTA
GMLALSWALALGLVLLLPPW---SVKRVSVLNFHLLHQLPGCAAAAAAFPGAQHA---HP
RRAQRRLSGLSVLLLCCVFLLATQPLVWVSLASGFS---VPWGVHAASWLLCCALSALNP
LLYTWRNEEFRRSV
>Q5KU14_HUMAN
VLSVVETTVLGLIFVVSLLGNVCALVLVARRRR---GATASLVLNLFCADLLFTSAIPLV
LVVRW---WLLGPVVCHLLFYVMTMSGSVTILTLAAVSLERMVCIVRLRR---PGRRTQA
ALLAFIWGYSALAALPLCIL---GEISWDVFFVTLNFLVPGLVIVISYSKILQIT---IR
VSQQDYRLFRTLFLLMVSFFIMWSPIIITILLILIQ---IWPSLFFWVVAFTFANSALNP
ILYNMSLFRNEWRK
