Package: bbssr
Type: Package
Title: Blinded Sample Size Re-Estimation for Binary Endpoints
Version: 1.0.2
Date: 2025-06-14
Authors@R: person("Gosuke", "Homma", email = "my.name.is.gosuke@gmail.com", 
                  role = c("aut", "cre"))
Description: Provides comprehensive tools for blinded sample size re-estimation (BSSR) 
    in two-arm clinical trials with binary endpoints. Unlike traditional fixed-sample 
    designs, BSSR allows adaptive sample size adjustments during trials while 
    maintaining statistical integrity and study blinding. Implements five exact 
    statistical tests: Pearson chi-squared, Fisher exact, Fisher mid-p, Z-pooled 
    exact unconditional, and Boschloo exact unconditional tests. Supports restricted, 
    unrestricted, and weighted BSSR approaches with exact Type I error control.
    Statistical methods based on Mehrotra et al. (2003) <doi:10.1111/1541-0420.00051> 
    and Kieser (2020) <doi:10.1007/978-3-030-49528-2_21>.
License: MIT + file LICENSE
URL: https://github.com/gosukehommaEX/bbssr
BugReports: https://github.com/gosukehommaEX/bbssr/issues
Depends: R (>= 3.5.0)
Imports: fpCompare, stats
Suggests: testthat (>= 3.0.0), knitr, rmarkdown, dplyr, ggplot2,
        tibble, tidyr, Exact, exact2x2, microbenchmark
VignetteBuilder: knitr
Encoding: UTF-8
RoxygenNote: 7.3.2
Config/testthat/edition: 3
NeedsCompilation: no
Packaged: 2025-06-17 15:59:41 UTC; i_lik
Author: Gosuke Homma [aut, cre]
Maintainer: Gosuke Homma <my.name.is.gosuke@gmail.com>
Repository: CRAN
Date/Publication: 2025-06-18 12:00:06 UTC
Built: R 4.6.0; ; 2026-04-25 23:53:27 UTC; unix
