Package: SpaCCI
Type: Package
Title: Spatially Aware Cell-Cell Interaction Analysis
Version: 1.0.5
Date: 2026-02-26
Authors@R: person(given = "Li-Ting",
                  family = "Ku",
                  role = c("aut", "cre"),
                  email = "lku@mdanderson.org")
Maintainer: Li-Ting Ku <lku@mdanderson.org>
Description: Provides tools for analyzing spatial cell-cell interactions based on ligand-receptor pairs, including functions for local, regional, and global analysis using spatial transcriptomics data. Integrates with databases like 'CellChat' <https://github.com/jinworks/CellChat>, 'CellPhoneDB' <https://www.cellphonedb.org/>, 'Cellinker' <https://www.rna-society.org/cellinker/>, 'ICELLNET' <https://github.com/soumelis-lab/ICELLNET>, and 'ConnectomeDB' <https://humanconnectome.org/software/connectomedb/> to identify ligand-receptor pairs, visualize interactions through heatmaps, chord diagrams, and infer interactions on different spatial scales. 
License: GPL (>= 2)
Encoding: UTF-8
Depends: R (>= 3.5.0)
Imports: Rcpp (>= 1.0.13), Seurat (>= 4.0.0), nnls, ggrepel, pheatmap,
        circlize (>= 0.4.12), Matrix, dplyr, patchwork, grDevices,
        reshape2, graphics, ggplot2, FNN, rlang
LinkingTo: Rcpp, RcppArmadillo
RoxygenNote: 7.3.3
NeedsCompilation: yes
Packaged: 2026-02-27 03:48:47 UTC; lku
Author: Li-Ting Ku [aut, cre]
Repository: CRAN
Date/Publication: 2026-02-27 08:30:23 UTC
Built: R 4.6.0; aarch64-apple-darwin23; 2026-04-26 21:44:51 UTC; unix
Archs: SpaCCI.so.dSYM
