R: Scalable Exact Algorithm for Large-Scale Set-Based Gene-Environment Interaction Tests

# Scalable Exact Algorithm for Large-Scale Set-Based Gene-Environment Interaction Tests

## Documentation for package ‘SEAGLE’ version 1.0.1

- DESCRIPTION file
- User guides, package vignettes and other documentation
- Package README

## Help Pages

applyAt | Function for applying t(A) on the left for REML EM
cosihap | Synthetic haplotype data generated from COSI software
estimate.vc | REML EM Algorithm
makeSimData | Generate synthetic data according to a fixed effects model
prep.SEAGLE | Prepare data for input into SEAGLE function
Rinv.AtG | Function for applying R inverse to AtG in REML EM algorithm
Rinv.u | Function for applying R inverse to u in REML EM algorithm
SEAGLE | Compute score-like test statistic and p-value for GxE test with SEAGLE algorithm
Vinv | Function for applying V inverse in Algorithm 1