Package: MultisiteMediation
Version: 0.0.4
Date: 2021-09-02
Title: Causal Mediation Analysis in Multisite Trials
Author: Xu Qin, Guanglei Hong, Jonah Deutsch, and Edward Bein
Maintainer: Xu Qin <xuqin@pitt.edu>
Depends: lme4, statmod, psych, MASS, ggplot2
Description: Multisite causal mediation analysis using the methods proposed by Qin and Hong (2017) <doi:10.3102/1076998617694879>, Qin, Hong, Deutsch, and Bein (2019) <doi:10.1111/rssa.12446>, and Qin, Deutsch, and Hong (2021) <doi:10.1002/pam.22268>. It enables causal mediation analysis in multisite trials, in which individuals are assigned to a treatment or a control group at each site. It allows for estimation and hypothesis testing for not only the population average but also the between-site variance of direct and indirect effects transmitted through one single mediator or two concurrent (conditionally independent) mediators. This strategy conveniently relaxes the assumption of no treatment-by-mediator interaction while greatly simplifying the outcome model specification without invoking strong distributional assumptions. This package also provides a function that can further incorporate a sample weight and a nonresponse weight for multisite causal mediation analysis in the presence of complex sample and survey designs and non-random nonresponse, to enhance both the internal validity and external validity. The package also provides a weighting-based balance checking function for assessing the remaining overt bias.
License: GPL-2
RoxygenNote: 7.1.1
URL: https://github.com/Xu-Qin/MultisiteMediation
BugReports: https://github.com/Xu-Qin/MultisiteMediation/issues
NeedsCompilation: no
Packaged: 2021-09-05 15:38:31 UTC; XUQIN
Repository: CRAN
Date/Publication: 2021-09-05 16:00:02 UTC
Built: R 4.6.0; ; 2026-04-26 09:00:40 UTC; unix
