Package: MiRKAT
Title: Microbiome Regression-Based Kernel Association Tests
Version: 1.2.3
Authors@R: c(person("Anna", "Plantinga", role = c("aut", "cre"), email = "amp9@williams.edu"),
             person("Nehemiah", "Wilson", role = c("aut", "ctb")),
             person("Haotian", "Zheng", role = c("aut", "ctb")),
             person("Tianying", "Wang", role = c("aut", "ctb")), 
             person("Xiang", "Zhan", role = c("aut", "ctb")),
             person("Michael", "Wu", role = "aut"),
             person("Ni", "Zhao", role = c("aut", "ctb")),
	           person("Jun", "Chen", role = "aut"))
Maintainer: Anna Plantinga <amp9@williams.edu>
Description: Test for overall association between microbiome composition data 
  and phenotypes via phylogenetic kernels. The phenotype can be univariate 
  continuous or binary (Zhao et al. (2015) <doi:10.1016/j.ajhg.2015.04.003>), 
  survival outcomes (Plantinga et al. (2017) <doi:10.1186/s40168-017-0239-9>), 
  multivariate (Zhan et al. (2017) <doi:10.1002/gepi.22030>) and 
  structured phenotypes (Zhan et al. (2017) <doi:10.1111/biom.12684>). 
  The package can also use robust regression (unpublished work) and 
  integrated quantile regression (Wang et al. (2021) <doi:10.1093/bioinformatics/btab668>). 
  In each case, the microbiome community effect is modeled nonparametrically 
  through a kernel function, which can incorporate phylogenetic tree information. 
Depends: R (>= 3.1.0)
License: GPL (>= 2)
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.2.3
NeedsCompilation: no
Imports: MASS, CompQuadForm, quantreg, GUniFrac, PearsonDS, lme4,
        Matrix, permute, mixtools, survival, stats
Suggests: knitr, vegan, rmarkdown, magrittr, kableExtra
VignetteBuilder: knitr, rmarkdown
Packaged: 2023-02-15 23:09:07 UTC; anna
Author: Anna Plantinga [aut, cre],
  Nehemiah Wilson [aut, ctb],
  Haotian Zheng [aut, ctb],
  Tianying Wang [aut, ctb],
  Xiang Zhan [aut, ctb],
  Michael Wu [aut],
  Ni Zhao [aut, ctb],
  Jun Chen [aut]
Repository: CRAN
Date/Publication: 2023-02-17 14:50:02 UTC
Built: R 4.6.0; ; 2026-04-26 19:46:06 UTC; unix
