Package: LTFHPlus
Type: Package
Title: Implementation of LT-FH++
Version: 2.2.0
Authors@R: c(
    person("Emil Michael", "Pedersen", email = "emp@ph.au.dk", role = c("aut", "cre")),
    person("Florian", "Privé", email = "florian.prive.21@gmail.com", role = c("aut", "ths")),
    person("Bjarni Jóhann", "Vilhjálmsson", email = "bjv@econ.au.dk", role = "ths"),
    person("Esben", "Agerbo", email = "ea@econ.au.dk", role = "ths"),
    person("Jette", "Steinbach", , "jst@econ.au.dk", role = "aut"),
    person("Lucas", "Rasmussen", email = "lar.ncrr@au.dk", role = "ctb"))
Description: Implementation of LT-FH++, an extension of
    the liability threshold family history (LT-FH) model.
    LT-FH++ uses a Gibbs sampler for sampling from the truncated 
    multivariate normal distribution and allows for 
    flexible family structures. LT-FH++ was first described in 
    Pedersen, Emil M., et al. (2022) 
    <doi:10.1016/j.ajhg.2022.01.009> 
    as an extension to LT-FH with more flexible family structures, 
    and again as the age-dependent liability threshold (ADuLT) model
    Pedersen, Emil M., et al. (2023) 
    <https://www.nature.com/articles/s41467-023-41210-z> 
    as an alternative to traditional time-to-event genome-wide
    association studies, where family history was not considered.
License: GPL-3
Imports: batchmeans, dplyr, future.apply, future, purrr, Rcpp, rlang,
        stats, stringr, tibble, tmvtnorm, tidyselect, igraph, xgboost,
        tidyr, ggplot2
Suggests: MASS, knitr, rmarkdown, kinship2, testthat
LinkingTo: Rcpp
Encoding: UTF-8
RoxygenNote: 7.3.3
Language: en-GB
URL: https://emilmip.github.io/LTFHPlus/,
        https://github.com/EmilMiP/LTFHPlus
BugReports: https://github.com/EmilMiP/LTFHPlus/issues
NeedsCompilation: yes
Packaged: 2025-11-17 09:58:16 UTC; au483192
Author: Emil Michael Pedersen [aut, cre],
  Florian Privé [aut, ths],
  Bjarni Jóhann Vilhjálmsson [ths],
  Esben Agerbo [ths],
  Jette Steinbach [aut],
  Lucas Rasmussen [ctb]
Maintainer: Emil Michael Pedersen <emp@ph.au.dk>
Repository: CRAN
Date/Publication: 2025-11-17 10:10:02 UTC
Built: R 4.6.0; aarch64-apple-darwin23; 2026-04-26 19:31:01 UTC; unix
Archs: LTFHPlus.so.dSYM
