Package: KinformR
Title: Relationship-Informed Pedigree and Variant Scoring
Version: 0.1.2
Authors@R: 
    person("Cameron M.", "Nugent", , "cam.nugent@sequencebio.com", role = c("aut", "cre"),
           comment = c(ORCID = "0000-0002-1135-2605"))
Maintainer: Cameron M. Nugent <cam.nugent@sequencebio.com>
Description: 
    Comparative evaluation of families and candidate variants in
    rare-variant association studies. The package can be used for
    two methodologically overlapping but distinct purposes. First, the prior to any genetic or genomic
    evaluation, evaluation of relative detection power of pedigrees, can direct recruitment
    efforts by showing which individuals not yet sampled would be the most meaningful additions to a study.
    Second, after sequencing and analysis,  variants based on association with disease status
    and familial relationships of individuals, aids in variant prioritization.
    Methodology is described in 
    Nugent (2025) <doi:10.1101/2025.10.06.25337426>.
License: MIT + file LICENSE
URL: https://github.com/SequenceBio/KinformR
BugReports: https://github.com/SequenceBio/KinformR/issues
Encoding: UTF-8
RoxygenNote: 7.3.2
VignetteBuilder: knitr
Suggests: devtools, testthat, knitr, rmarkdown
NeedsCompilation: no
Packaged: 2026-02-12 18:18:32 UTC; cam.nugent@sequencebio.com
Author: Cameron M. Nugent [aut, cre] (ORCID:
    <https://orcid.org/0000-0002-1135-2605>)
Repository: CRAN
Date/Publication: 2026-02-17 15:50:02 UTC
Built: R 4.6.0; ; 2026-04-25 19:53:52 UTC; unix
