R: Kalman Reaction Networks

# Kalman Reaction Networks

## Documentation for package ‘Karen’ version 1.0

- DESCRIPTION file
- User guides, package vignettes and other documentation

## Help Pages

get.cdn | Get the cell differentiation network from a fitted Kalman Reaction Network.
get.fit | Fit the state-space model to a clonal tracking dataset
get.sim.trajectories | Simulate a clonal tracking dataset from a given cell differentiation network.
get.sMoments | Get the first two-order smoothing moments from a fitted Kalman Reaction Network.
get.sMoments.avg | Get the clone-average of the first two-order smoothing moments from a fitted Kalman Reaction Network.
nearestPD | Nearest Positive Definite Matrix
Y_CT | Clonal tracking data from clinical trials
Y_RM | Rhesus Macaque clonal tracking dataset