Type: Package
Package: DTSEA
Title: Drug Target Set Enrichment Analysis
Version: 0.0.3
Authors@R: c(person(given = "Junwei", family = "Han", email = "hanjunwei1981@163.com", role  = c("aut", "cre", "cph")),
             person(given = "Yinchun", family = "Su", role  = "aut"))
Maintainer: Junwei Han <hanjunwei1981@163.com>
Description: It is a novel tool used to identify the candidate drugs against a particular disease based on the drug target set enrichment analysis. It assumes the most effective drugs are those with a closer affinity in the protein-protein interaction network to the specified disease. (See Gómez-Carballa et al. (2022) <doi: 10.1016/j.envres.2022.112890> and Feng et al. (2022) <doi: 10.7150/ijms.67815> for disease expression profiles; see Wishart et al. (2018) <doi: 10.1093/nar/gkx1037> and Gaulton et al. (2017) <doi: 10.1093/nar/gkw1074> for drug target information; see Kanehisa et al. (2021) <doi: 10.1093/nar/gkaa970> for the details of KEGG database.)
License: GPL (>= 2)
Depends: R (>= 4.0.0)
Imports: dplyr, fgsea, igraph, magrittr, tibble, tidyr, BiocParallel,
        stringr
Suggests: knitr, rmarkdown
VignetteBuilder: knitr
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.2.1
NeedsCompilation: no
Packaged: 2022-11-06 08:45:55 UTC; syc
Author: Junwei Han [aut, cre, cph],
  Yinchun Su [aut]
Repository: CRAN
Date/Publication: 2022-11-06 13:20:02 UTC
Built: R 4.6.0; ; 2026-04-26 17:46:41 UTC; unix
