R: CFO-Type Designs in Phase I/II Clinical Trials

# CFO-Type Designs in Phase I/II Clinical Trials

## Documentation for package ‘CFO’ version 2.2.0

- DESCRIPTION file

## Help Pages

aCFO.next | Determination of the dose level for next cohort in the accumulative calibration-free odds (aCFO) design for phase I trials
CFO.next | Determination of the dose level for next cohort in the calibration-free odds (CFO) design for phase I trials
CFO.oc | Generate operating characteristics of phase I trials single-drug trials in multiple simulations
CFO.selectmtd | Select the maximum tolerated dose (MTD) for the real single-drug trials
CFO.simu | Conduct one simulation using the calibration-free odds (CFO), accumulative CFO (aCFO) design, or randomized CFO (rCFO) design for phase I trials.
CFO2d.next | Determinate the dose level for the next cohort in the two-dimensional calibration-free odds (2dCFO) design for phase I trials.
CFO2d.oc | Generate operating characteristics of phase I drug-combination trials in multiple simulations
CFO2d.selectmtd | Select the maximum tolerated dose (MTD) for the real drug combination trials
CFO2d.simu | Conduct one simulation using the two-dimensional calibration-free odds (2dCFO) design for phase I trials.
CFOeff.next | Determination of the dose level for next cohort in the calibration-free odds (CFO) design for phase I/II trials
CFOeff.oc | Generate operating characteristics of phase I/II trials single-drug trials in multiple simulations.
CFOeff.selectobd | Select the optimal biological dose (OBD) for the real single-drug trials
CFOeff.simu | Conduct one simulation using the calibration-free odds (CFO) design for phase I/II trials
gammatable | Generating table of threshold gamma_L and gamma_R in the calibration-free odds (CFO) design
lateonset.next | Determination of the dose level for next cohort in the calibration-free odds type (CFO-type) design with late-onset toxicity for phase I trials
lateonset.simu | Conduct one simulation using the calibration-free odds type (CFO-type) design with late-onset toxicity for phase I trials.
pCFO.next | Determination of the dose level for next cohort in the precision calibration-free odds (pCFO) design for phase I trials
plot.cfo | Plot the results by other functions
print.cfo | Generate descriptive summary for objects returned by other functions
rCFO.next | Determination of the dose level for next cohort in the randomized calibration-free odds (rCFO) design for phase I trials
summary.cfo | Generate descriptive summary for objects returned by other functions