Package: ActiveDriverWGS
Title: A Driver Discovery Tool for Cancer Whole Genomes
Version: 1.2.1
Authors@R: c(
	person("Juri", "Reimand", email = "juri.reimand@utoronto.ca", role = c("aut", "cre")), 
	person("Helen", "Zhu", email = "helen.zhu@oicr.on.ca", role = c("ctb")), 
	person("Kevin", "Cheng", email = "kevin.cheng@oicr.on.ca", role = "ctb"))
Description: A method for finding enrichments of somatic single nucleotide variants (SNVs) and small insertions-deletions (Indels) in functional elements in the human genome. 'ActiveDriverWGS' detects coding and noncoding cancer driver elements using whole genome sequencing data. The method is part of the publication H. Zhu et al. (2020) <doi:10.1016/j.molcel.2019.12.027> "Candidate Cancer Driver Mutations in Distal Regulatory Elements and Long-Range Chromatin Interaction Networks" in Molecular Cell. 
Depends: R (>= 3.5)
Imports: BSgenome, Biostrings, GenomeInfoDb, GenomicRanges, IRanges,
        S4Vectors
License: GPL-3
Encoding: UTF-8
LazyData: true
Suggests: BSgenome.Hsapiens.UCSC.hg19, BSgenome.Hsapiens.UCSC.hg38,
        BSgenome.Mmusculus.UCSC.mm9, BSgenome.Mmusculus.UCSC.mm10,
        knitr, testthat, rmarkdown
VignetteBuilder: knitr
RoxygenNote: 7.3.2
NeedsCompilation: no
Packaged: 2026-03-09 13:24:40 UTC; jreimand
Author: Juri Reimand [aut, cre],
  Helen Zhu [ctb],
  Kevin Cheng [ctb]
Maintainer: Juri Reimand <juri.reimand@utoronto.ca>
Repository: CRAN
Date/Publication: 2026-03-13 13:00:08 UTC
Built: R 4.6.0; ; 2026-04-25 15:58:35 UTC; unix
