R: Utilities and Design Aids for Up-and-Down Dose-Finding Studies

# Utilities and Design Aids for Up-and-Down Dose-Finding Studies

## Documentation for package ‘upndown’ version 0.3.0

- DESCRIPTION file
- User guides, package vignettes and other documentation

## Help Pages

bcd | Up-and-Down Design Rules for use in Dose-Finding Simulator
bcdmat | Transition Probability Matrices for Up-and-Down Designs
bcoin | Up-and-Down Target Calculation and Design Guidance
checkCDF | Data Validation Utilities for 'upndown'
checkDose | Data Validation Utilities for 'upndown'
checkNatural | Data Validation Utilities for 'upndown'
checkResponse | Data Validation Utilities for 'upndown'
checkTarget | Data Validation Utilities for 'upndown'
classicmat | Transition Probability Matrices for Up-and-Down Designs
cumulvec | Key Probability Vectors of Up-and-Down Designs
currentvec | Key Probability Vectors of Up-and-Down Designs
dfboot | Generic percentile dose-response / dose-finding bootstrap routine
dfsim | Generalized Dose-Finding Ensemble Simulator
dixonmood | Original Dixon and Mood (1948) point estimate
drplot | Visualizing the dose-response summary of an up-and-down experiment
dynamean | Up-and-Down target-dose averaging estimate, with dynamic cutoff-point
g2targ | Up-and-Down Target Calculation and Design Guidance
groupUD | Up-and-Down Design Rules for use in Dose-Finding Simulator
gtargOptions | Up-and-Down Target Calculation and Design Guidance
gudmat | Transition Probability Matrices for Up-and-Down Designs
k2targ | Up-and-Down Target Calculation and Design Guidance
kmatFull | Transition Probability Matrices for Up-and-Down Designs
kmatMarg | Transition Probability Matrices for Up-and-Down Designs
krow | Up-and-Down Design Rules for use in Dose-Finding Simulator
ktargOptions | Up-and-Down Target Calculation and Design Guidance
pivec | Key Probability Vectors of Up-and-Down Designs
reversals | Reversal-anchored averaging estimators for Up-and-Down
reversmean | Reversal-anchored averaging estimators for Up-and-Down
udest | Centered-Isotonic-Regression (CIR) Estimate for the Up-and-Down Target Dose
udplot | Visualizing the time series of an up-and-down experiment
validUDinput | Data Validation Utilities for 'upndown'