Package: surrosurv
Type: Package
Title: Evaluation of Failure Time Surrogate Endpoints in Individual
        Patient Data Meta-Analyses
Version: 1.1.27
Authors@R: c(
  person("Federico", "Rotolo", role="aut", email="federico.rotolo@gustaveroussy.fr",
          comment = c(ORCID = "0000-0003-4837-6501")),
  person("Xavier", "Paoletti", role="ctb"),
  person("Marc", "Buyse", role="ctb"),
  person("Tomasz", "Burzykowski", role="ctb"),
  person("Stefan", "Michiels", role="ctb", email="stefan.michiels@gustaveroussy.fr",
          comment = c(ORCID = "0000-0002-6963-2968")),
  person("Dan", "Chaltiel", role="cre", email="dan.chaltiel@gustaveroussy.fr",
          comment = c(ORCID = "0000-0003-3488-779X")))
Maintainer: Dan Chaltiel <dan.chaltiel@gustaveroussy.fr>
Description: Provides functions for the evaluation of
    surrogate endpoints when both the surrogate and the true endpoint are failure
    time variables. The approaches implemented are:
    (1) the two-step approach (Burzykowski et al, 2001) <DOI:10.1111/1467-9876.00244> with a copula model (Clayton, Plackett, Hougaard) at
    the first step and either a linear regression of log-hazard ratios at the second
    step (either adjusted or not for measurement error);
    (2) mixed proportional hazard models estimated via mixed Poisson GLM
    (Rotolo et al, 2017 <DOI:10.1177/0962280217718582>).
Depends: R (>= 3.5.0)
Imports: copula, eha, grDevices, lme4, MASS, Matrix, msm, mvmeta,
        optimx, parallel, parfm, stats, survival
License: GPL-2
URL: https://github.com/Oncostat/surrosurv
BugReports: https://github.com/Oncostat/surrosurv/issues/
VignetteBuilder: R.rsp
Suggests: R.rsp, testthat (>= 3.0.0)
Encoding: UTF-8
Config/testthat/edition: 3
NeedsCompilation: no
Packaged: 2025-10-10 08:45:08 UTC; Dan
Author: Federico Rotolo [aut] (ORCID: <https://orcid.org/0000-0003-4837-6501>),
  Xavier Paoletti [ctb],
  Marc Buyse [ctb],
  Tomasz Burzykowski [ctb],
  Stefan Michiels [ctb] (ORCID: <https://orcid.org/0000-0002-6963-2968>),
  Dan Chaltiel [cre] (ORCID: <https://orcid.org/0000-0003-3488-779X>)
Repository: CRAN
Date/Publication: 2025-10-10 09:10:02 UTC
Built: R 4.6.0; ; 2026-04-28 21:52:58 UTC; unix
