Package: simFastBOIN
Type: Package
Title: Fast Bayesian Optimal Interval Design for Phase I Dose-Finding
        Trials
Version: 1.3.2
Date: 2025-12-06
Authors@R: person(given = "Gosuke",
                  family = "Homma",
                  role = c("aut", "cre"),
                  email = "my.name.is.gosuke@gmail.com",
                  comment = c(ORCID = "0000-0002-6854-5627"))
Description: 
    Conducting Bayesian Optimal Interval (BOIN) design for phase I 
    dose-finding trials. 'simFastBOIN' provides functions for pre-computing 
    decision tables, conducting trial simulations, and evaluating operating 
    characteristics. The package uses vectorized operations and the 
    Iso::pava() function for isotonic regression to achieve efficient 
    performance while maintaining full compatibility with BOIN methodology. 
    Version 1.3.2 adds p_saf and p_tox parameters for customizable safety and 
    toxicity thresholds. Version 1.3.1 fixes Date field. Version 1.2.1 adds 
    comprehensive 'roxygen2' documentation and enhanced print formatting with 
    flexible table output options. Version 1.2.0 integrated C-based PAVA for 
    isotonic regression. Version 1.1.0 introduced conservative MTD selection 
    (boundMTD) and flexible early stopping rules (n_earlystop_rule). Methods 
    are described in Liu and Yuan (2015) <doi:10.1111/rssc.12089>.
License: MIT + file LICENSE
Imports: knitr, kableExtra, Iso, stats
Suggests: testthat (>= 3.0.0), rmarkdown
Encoding: UTF-8
RoxygenNote: 7.3.3
Language: en-US
URL: https://github.com/gosukehommaEX/simFastBOIN
BugReports: https://github.com/gosukehommaEX/simFastBOIN/issues
Config/testthat/edition: 3
VignetteBuilder: knitr
NeedsCompilation: no
Packaged: 2025-12-11 14:05:14 UTC; i_lik
Author: Gosuke Homma [aut, cre] (ORCID:
    <https://orcid.org/0000-0002-6854-5627>)
Maintainer: Gosuke Homma <my.name.is.gosuke@gmail.com>
Repository: CRAN
Date/Publication: 2025-12-17 10:20:02 UTC
Built: R 4.6.0; ; 2026-04-28 21:22:23 UTC; unix
