Package: rxode2
Version: 5.1.2
Title: Facilities for Simulating from ODE-Based Models
Authors@R: c(
   person("Matthew L.","Fidler", role = c("aut", "cre"), email = "matthew.fidler@gmail.com", comment=c(ORCID="0000-0001-8538-6691")),
   person("Wenping", "Wang", role = c("aut"), email = "wwang8198@gmail.com"),
   person("Alan", "Hindmarsh",role="ctb"),
   person("Arun", "Srinivasan", role="ctb", email="arunkumar.sriniv@gmail.com"),
   person("Awad H.", "Al-Mohy",role="ctb"),
   person("Bill", "Denney", email="wdenney@humanpredictions.com", role="ctb", comment=c(ORCID="0000-0002-5759-428X")),
   person("Cleve", "Moler", role="ctb"),
   person("David", "Cooley", role="ctb"),
   person("Drew", "Schmidt", role="ctb"),
   person("Ernst", "Hairer", role="ctb"),
   person("Gabriel", "Staples", role="ctb"),
   person("Gerhard", "Wanner", role="ctb"),
   person("Gilbert", "Stewart", role="ctb"),
   person("Goro", "Fuji",  role="ctb", email="gfuji@cpan.org"),
   person("Hadley", "Wickham", role="ctb"),
   person("Igor", "Kushnir", email="igorkuo@gmail.com", role="ctb"),
   person("Jack", "Dongarra", role="ctb"),
   person("Jim", "Bunch", role="ctb"),
   person("Kevin", "Ushey", role="ctb"),
   person("Linda", "Petzold", role="ctb"),
   person("Martin", "Maechler", role="ctb"),
   person("Matt", "Dowle", role="ctb", email="mattjdowle@gmail.com"),
   person("Matteo", "Fasiolo", email = "matteo.fasiolo@gmail.com", role = "ctb"),
   person("Melissa", "Hallow", role = "aut", email = "hallowkm@uga.edu"),
   person("Michel", "Lang", , "michellang@gmail.com", role = "ctb"),
   person("Morwenn","", role="ctb"),
   person("Nicholas J.", "Higham",role="ctb"),
   person("Omar", "Elashkar", email="omar.i.elashkar@gmail.com", role="ctb"),
   person("Richard", "Upton", role = "ctb"),
   person("Roger B.", "Sidje", role="ctb"),
   person("Simon", "Frost", role="ctb"),
   person("Yu", "Feng", role="ctb"),
   person("Zufar", "Mulyukov", role="ctb", email="zufar.mulyukov@novartis.com"))
Maintainer: Matthew L. Fidler <matthew.fidler@gmail.com>
Depends: R (>= 4.1.0)
Suggests: Matrix, DT, covr, crayon, curl, digest, dplyr (>= 0.8.0),
        ggrepel, gridExtra, htmltools, knitr, learnr, microbenchmark,
        nlme, remotes, rlang, rmarkdown, scales, shiny, stringi,
        symengine, testthat, tidyr, usethis, withr, xgxr, pillar,
        tibble, units (>= 0.6-0), rsconnect, devtools, patchwork,
        nlmixr2data, lifecycle, kableExtra, pmxTools, rootSolve, memuse
Imports: PreciseSums (>= 0.7), Rcpp (>= 0.12.3), backports, cli (>=
        2.0.0), checkmate, ggplot2 (>= 3.4.0), inline, lotri (>=
        1.0.4), memoise, methods, rex, sys, tools, utils, dparser (>=
        1.3.1-12), rxode2ll (>= 2.0.9), data.table (>= 1.12.4), qs2,
        vctrs, stats
Description: Facilities for running simulations from ordinary
    differential equation ('ODE') models, such as pharmacometrics and other
    compartmental models.  A compilation manager translates the ODE model
    into C, compiles it, and dynamically loads the object code into R for
    improved computational efficiency.  An event table object facilitates
    the specification of complex dosing regimens (optional) and sampling
    schedules.  NB: The use of this package requires both C and
    Fortran compilers, for details on their use with R please see
    Section 6.3, Appendix A, and Appendix D in the "R Administration and
    Installation" manual. Also the code is mostly released under GPL.  The
    'VODE' and 'LSODA' are in the public domain.  The information is available
    in the inst/COPYRIGHTS.
BugReports: https://github.com/nlmixr2/rxode2/issues/
NeedsCompilation: yes
VignetteBuilder: knitr
License: GPL (>= 3)
URL: https://nlmixr2.github.io/rxode2/,
        https://github.com/nlmixr2/rxode2/
Biarch: true
LinkingTo: sitmo, lotri (>= 1.0.0), PreciseSums (>= 0.7), Rcpp,
        RcppArmadillo (>= 0.9.300.2.0), BH, RcppParallel, RcppEigen (>=
        0.3.3.9.2), StanHeaders (>= 2.21.0.7), dparser (>= 1.3.1-12)
Encoding: UTF-8
LazyData: true
Language: en-US
Config/testthat/edition: 3
Config/roxygen2/version: 8.0.0
Packaged: 2026-06-01 21:41:08 UTC; matt-fidler
Author: Matthew L. Fidler [aut, cre] (ORCID:
    <https://orcid.org/0000-0001-8538-6691>),
  Wenping Wang [aut],
  Alan Hindmarsh [ctb],
  Arun Srinivasan [ctb],
  Awad H. Al-Mohy [ctb],
  Bill Denney [ctb] (ORCID: <https://orcid.org/0000-0002-5759-428X>),
  Cleve Moler [ctb],
  David Cooley [ctb],
  Drew Schmidt [ctb],
  Ernst Hairer [ctb],
  Gabriel Staples [ctb],
  Gerhard Wanner [ctb],
  Gilbert Stewart [ctb],
  Goro Fuji [ctb],
  Hadley Wickham [ctb],
  Igor Kushnir [ctb],
  Jack Dongarra [ctb],
  Jim Bunch [ctb],
  Kevin Ushey [ctb],
  Linda Petzold [ctb],
  Martin Maechler [ctb],
  Matt Dowle [ctb],
  Matteo Fasiolo [ctb],
  Melissa Hallow [aut],
  Michel Lang [ctb],
  Morwenn [ctb],
  Nicholas J. Higham [ctb],
  Omar Elashkar [ctb],
  Richard Upton [ctb],
  Roger B. Sidje [ctb],
  Simon Frost [ctb],
  Yu Feng [ctb],
  Zufar Mulyukov [ctb]
Repository: CRAN
Date/Publication: 2026-06-02 07:20:02 UTC
Built: R 4.6.0; x86_64-apple-darwin20; 2026-06-02 09:45:59 UTC; unix
