Package: presmoothedTP
Type: Package
Title: Presmoothed Landmark Aalen-Johansen Estimator of Transition
        Probabilities for Complex Multi-State Models
Version: 0.1.0
Authors@R: c(
	person(
		given = "Gustavo",
		family = "Soutinho",
		role = c("aut", "cre"),
		email = "gustavosoutinho@sapo.pt",
		comment = c(ORCID = "0000-0002-0559-1327")
	),
	person(
		given = "Luis",
		family = "Meira-Machado",
		role = "aut",
		email = "lmachado@math.uminho.pt",
		comment = c(ORCID = "0000-0002-8577-7665")
	)
	)
Description: Multi-state models are essential tools in longitudinal data analysis. 
             One primary goal of these models is the estimation of transition 
             probabilities, a critical metric for predicting clinical prognosis 
             across various stages of diseases or medical conditions. Traditionally, 
             inference in multi-state models relies on the Aalen-Johansen (AJ) 
             estimator which is consistent under the Markov assumption. However, 
             in many practical applications, the Markovian nature of the process
             is often not guaranteed, limiting the applicability of the AJ
             estimator in more complex scenarios. This package extends the landmark Aalen-Johansen
             estimator (Putter, H, Spitoni, C (2018) <doi:10.1177/0962280216674497>)
             incorporating presmoothing techniques described by Soutinho, 
             Meira-Machado and Oliveira (2020) <doi:10.1080/03610918.2020.1762895>, 
             offering a robust alternative for estimating transition probabilities
             in non-Markovian multi-state models with multiple states and potential
             reversible transitions.
License: GPL-3
Depends: R (>= 3.5.0)
Imports: survival, mstate, plyr
RoxygenNote: 7.3.1
Encoding: UTF-8
LazyLoad: yes
LazyData: yes
NeedsCompilation: yes
Packaged: 2025-01-20 21:07:03 UTC; AEFH
Author: Gustavo Soutinho [aut, cre] (<https://orcid.org/0000-0002-0559-1327>),
  Luis Meira-Machado [aut] (<https://orcid.org/0000-0002-8577-7665>)
Maintainer: Gustavo Soutinho <gustavosoutinho@sapo.pt>
Repository: CRAN
Date/Publication: 2025-01-22 17:10:02 UTC
Built: R 4.6.0; ; 2026-04-27 19:25:13 UTC; unix
