[![Downloads](http://cranlogs.r-pkg.org/badges/pedgene)](https://CRAN.R-project.org/package=pedgene)

[![Total-Downloads](https://cranlogs.r-pkg.org/badges/grand-total/pedgene)](https://CRAN.R-project.org/package=pedgene)

# rpedgene (pedgene on CRAN)

Gene-level kernel and burden association tests of genetic variants with a trait of interest, allowing for related individuals, including twins.

# Authors

Daniel J. Schaid and Jason P. Sinnwell
Small contribution by A. Visconti

# Manuscript:

[Schaid DJ, McDonnell SK., Sinnwell JP, Thibodeau SN. (2013) **Multiple Genetic Variant Association Testing by Collapsing and Kernel Methods With Pedigree or Population Structured Data** *Genet Epidemiol*, 37(5):409-18](https://pubmed.ncbi.nlm.nih.gov/23650101/)

