# List of models

    knitr::kable(modeldb[, c("name", "description")])

name | description
--- | ---
PK_1cmt | One compartment PK model with linear clearance
PK_1cmt_des | One compartment PK model with linear clearance using differential equations
PK_2cmt | Two compartment PK model with linear clearance
PK_2cmt_des | Two compartment PK model with linear clearance using differential equations
PK_2cmt_no_depot | Two compartment PK model with linear clearance using differential equations
PK_2cmt_tdcl_des | Two compartment PK model with time-dependent clearance using differential equations (structured like nivolumab PK model)
PK_3cmt | Three compartment PK model with linear clearance
PK_3cmt_des | Three compartment PK model with linear clearance using differential equations
igg_kim_2006 | Immunoglobulin G (IgG) model for nonlinear metabolism in healthy subjects
phenylalanine_charbonneau_2021 | Phenylalanine model for absorption and metabolism in healthy subjects and patients with PKU
indirect_0cpt_transitEx | Two compartment PK model with Michealis-Menten clearance using differential equations
indirect_1cpt_inhi_kin | One compartment indirect response model with inhibition of kin.
indirect_1cpt_inhi_kin_CLV | One compartment indirect response model with inhibition of kin.
indirect_1cpt_inhi_kin_r0rmaxcrmax | One compartment indirect response model with inhibition of kin.
indirect_1cpt_inhi_kout | One compartment indirect response model with inhibition of kout.
indirect_1cpt_inhi_kout_CLV | One compartment indirect response model with inhibition of kout.
indirect_1cpt_inhi_kout_r0rmaxcrmax | One compartment indirect response model with inhibition of kout.
indirect_1cpt_stim_kin | One compartment indirect response model with stimulation of kin.Parameterized using rate cosntants
indirect_1cpt_stim_kin_CLV | One compartment indirect response model with stimulation of kin.
indirect_1cpt_stim_kin_r0rmaxcrmax | One compartment indirect response model with stimulation of kin.
indirect_1cpt_stim_kout | One compartment indirect response model with stimulation of kout.Parameterized using rate cosntants
indirect_1cpt_stim_kout_CLV | One compartment indirect response model with stimulation of kout.
indirect_1cpt_stim_kout_r0rmaxcrmax | One compartment indirect response model with stimulation of kout.
indirect_circ_1cpt_inhi_kin_kin_t | One compartment indirect response model with inhibition of kin and circadian kin_t.
indirect_circ_1cpt_inhi_kin_kout_t | One compartment indirect response model with inhibition of kin and circadian kin_t.
indirect_circ_1cpt_inhi_kout_kin_t | One compartment indirect response model with inhibition of kout and circadian kin_t.
indirect_circ_1cpt_inhi_kout_kout_t | One compartment indirect response model with inhibition of kout and circadian kin_t.
indirect_circ_1cpt_stim_kin_kin_t | One compartment indirect response model with stimulation of kin and circadian kin_t.Parameterized using rate cosntants
indirect_circ_1cpt_stim_kin_kout_t | One compartment indirect response model with stimulation of kin and circadian kout_t.Parameterized using rate constants
indirect_circ_1cpt_stim_kout_kin_t | One compartment indirect response model with stimulation of kout and circadian kin_t.Parameterized using rate cosntants
indirect_circ_1cpt_stim_kout_kout_t | One compartment indirect response model with stimulation of kout and circadian kout_t.Parameterized using rate cosntants
indirect_prec_1cpt_inhi_CLV | One compartment precursor-dependent indirect response model with inhibition of drug response. Parameterized with clearance and volume. (effect).
indirect_prec_1cpt_inhi_r0rmaxcrmax | One compartment precursor-dependent indirect response model with inhibition of drug response (effect).
indirect_prec_1cpt_stim_CLV | One compartment precursor-dependent indirect response model with inhibition of drug response (effect). Parameterized with clearance and volume
indirect_prec_1cpt_stim_r0rmaxcrmax | One compartment precursor-dependent indirect response model with inhibition of drug response (effect). Parameterized with clearance and volume
PK_2cmt_mAb_Davda_2014 | Two compartment PK model with linear clearance for average monoclonal antibodies (Davda 2014)
PK_double_sim_01 | PK double absorption model with simultaneous zero order and first order absorptions
PK_double_sim_10 | PK double absorption model with simultaneous first order and zero order absorptions
PK_double_sim_11 | PK double absorption model with simultaneous first order absorptions
CarlssonPetri_2021_liraglutide | Liraglutide PK model in adolescents (Carlsson Petri 2021)
Cirincione_2017_exenatide | Exenatide immediate-release PK model (Cirincione 2017)
Grimm_2023_gantenerumab | Gantenerumab PK model (Grimm 2017)
Grimm_2023_trontinemab | Trontinemab PK model (Grimm 2017)
Kovalenko_2020_dupilumab | Dupilumab PK model (Kovalenko 2020)
Kyhl_2016_nalmefene | NA
Soehoel_2022_tralokinumab | Tralokinumab PK model (Soehoel 2022)
Xie_2019_agomelatine | A semiphysiological population pharmacokinetic model of agomelatine and its metabolites in Chinese healthy volunteers
Zhu_2017_lebrikizumab | Lebrikizumab PK model (Zhu 2017)
oncology_sdm_lobo_2002 | Signal transduction model for delayed concentration effects on cancer cell growth
oncology_xenograft_simeoni_2004 | Oncology tumor growth model in xenograft models
tgi_no_sat_Koch | One compartment TGI model with with exponential tumor growth, without saturation.
tgi_no_sat_expo | One-compartment TGI model with exponential tumor growth, without saturation.
tgi_no_sat_linear | One compartment TGI model with with linear tumor growth, without saturation.
tgi_no_sat_powerLaw | One compartment TGI model with with exponential tumor growth, without saturation.
tgi_sat_Gompertz | One compartment TGI model with tumor growth proportional to tumor size through a generalized logistic function, with saturation.
tgi_sat_VonBertalanffy | One compartment TGI model where tumor growth is limited by a loss term, with saturation.
tgi_sat_genLogistic | One compartment TGI model with tumor growth proportional to tumor size through a generalized logistic function, with saturation.
tgi_sat_genVonBertalanffy | One compartment TGI model where tumor growth is limited by a loss term, with saturation.
tgi_sat_logistic | One compartment TGI model with with exponential tumor growth that decelerates linearly, with saturation.