# dinamic

DNA copy number changes (gains and losses) are commonly seen in tumor tissue.  Some copy
number changes provide a selective growth advantage, and these are observed in the same
genomic region across multiple samples.  These copy number changes are termed recurrent.
In contrast, sporadic copy number changes that occur randomly throughout the genome because
of underlying genomic instability are less likely to have biological relevance.  The
dinamic R package was designed to assess the statistical significance of recurrent DNA
copy number aberrations using the cyclic shift permutation scheme.

## Example

Please refer to the vignette.
