R: Clinical Trial Design and Data Analysis Functions

# Clinical Trial Design and Data Analysis Functions

## Documentation for package ‘clinfun’ version 1.1.5

- DESCRIPTION file
- User guides, package vignettes and other documentation
- Package NEWS

## Help Pages

aucVardiTest | Two-Sample Tests for Growth Curves under Dependent Right Censoring
bdrycross.prob | Stopping rule for toxicity/futility monitoring
calogrank | Survival curves analysis of covariance
coxphCPE | Concordance Probability Estimate for Cox model
coxphERR | Heller Explained Relative Risk
coxphQuantile | Survival time quantile as a function of covariate
CPS.ssize | Trial Designs Based On Fisher's Exact Test
deltaAUC | Comparing the AUC from ROC curves from nested binary regression
fe.mdor | Trial Designs Based On Fisher's Exact Test
fe.power | Trial Designs Based On Fisher's Exact Test
fe.ssize | Trial Designs Based On Fisher's Exact Test
fedesign | Trial Designs Based On Fisher's Exact Test
futilbdry | Stopping rule for toxicity/futility monitoring
gsdesign | Group Sequential Designs
gsdesign.binomial | Group Sequential Designs
gsdesign.normal | Group Sequential Designs
gsdesign.survival | Group Sequential Designs
ipmn | Comparing the AUC from ROC curves from nested binary regression
jonckheere.test | Exact/permutation version of Jonckheere-Terpstra test
ktau | Kendall's tau-b estimate
lines.roc.curve | Empirical ROC curve
mdrr | Trial Designs Based On Fisher's Exact Test
oc.twostage.bdry | Two-stage boundary operating characteristics
or2pcase | Trial Designs Based On Fisher's Exact Test
permlogrank | Permutation version of survdiff
ph2simon | Simon's 2-stage Phase II design
ph2single | Exact single stage Phase II design
plot.ph2simon | Simon's 2-stage Phase II design
plot.roc.curve | Empirical ROC curve
plot.roc.perm.test | Permutation test to compare ROC curve
power.ladesign | Power of k-sample rank test under Lehmann alternative
print.futilbdry | Stopping rule for toxicity/futility monitoring
print.ladesign | Power of k-sample rank test under Lehmann alternative
print.ph2simon | Simon's 2-stage Phase II design
print.roc.area.test | Nonparametric area under the ROC curve
print.roc.curve | Empirical ROC curve
print.roc.perm.test | Permutation test to compare ROC curve
print.toxbdry | Stopping rule for toxicity/futility monitoring
pselect | Probability of selection under pick the winner rule
roc.area.test | Nonparametric area under the ROC curve
roc.curve | Empirical ROC curve
roc.perm.test | Permutation test to compare ROC curve
ROCanalysis | Functions to plot and compare ROC curves.
rocanalysis | Functions to plot and compare ROC curves.
toxbdry | Stopping rule for toxicity/futility monitoring
twostage.admissible | Admissible design options between Minimax and Optimal
twostage.inference | Inference following a two-stage design for binary response