# admiralneuro

## Updates of Existing Functions

- Improved test coverage in `compute_centiloid()` function when invalid tracer combination is provided. The 
function also now only accepts positive SUVR values. (#106)

<details>
<summary>Developer Notes</summary>

- Aligned the templates' save directory with `{pharmaverseadam}` requirements. (#91)

</details>

## New features

- The function `compute_upsit_percentile()` calculates percentiles based on age, sex, and UPSIT scores. (# 95)

## Documentation

- Vignette "Creating ADNV". (#114)

## Template programs

- ADNV template scripts `ad_adnv.R` which creates a Nervous System Analysis Dataset. (#113)

## Various

- Moved test SDTM datasets `dm_neuro`, `nv_neuro`, `suppnv_neuro` and `ag_neuro` from `{admiralneuro}` to `{pharmaversesdtm}`. (#92)

- Updated the kapa.ai `data-modal-search-placeholder` to "Ask me a question about {admiralneuro} or the {admiral} ecosystem..." (#119)

# admiralneuro 0.1.0

- Initial package release mainly focused on Alzheimer’s disease specifically for the PET scan analysis.

## Functions

- The function `compute_centiloid()` computes centiloid values based on Amyloid PET tracer, SUVR value and pipeline, and reference region. (#21)

## Template programs

- ADAPET template scripts `ad_adapet.R` which creates an Amyloid PET Scan Analysis Dataset. (#25)
- ADTPET template scripts `ad_adtpet.R` which creates a Tau PET Scan Analysis Dataset. (#25)

## Documentation

- Vignette "Creating ADAPET and ADTPET". (#19)
