Package: adestr
Type: Package
Title: Estimation in Optimal Adaptive Two-Stage Designs
Version: 1.0.0
Authors@R: c(person("Jan", "Meis", role = c("aut", "cre"), email = "meis@imbi.uni-heidelberg.de", comment = c(ORCID = "0000-0001-5407-7220")),
  person("Martin", "Maechler", role = c("cph"), email = "maechler@stat.math.ethz.ch", comment = c(ORCID = "0000-0002-8685-9910", "Original author of monoSpl.c (from the 'stats' package).")))
Description: 
  Methods to evaluate the performance characteristics of
  various point and interval estimators for optimal adaptive two-stage designs as described
  in Meis et al. (2024) <doi:10.1002/sim.10020>.
  Specifically, this package is written to work with trial designs created by the 'adoptr' package
  (Kunzmann et al. (2021) <doi:10.18637/jss.v098.i09>; Pilz et al. (2021) <doi:10.1002/sim.8953>)).
  Apart from the a priori evaluation of performance characteristics, this package also allows for the
  evaluation of the implemented estimators on real datasets, and it implements methods
  to calculate p-values.
License: GPL (>= 2)
Copyright: This package contains a modified version of the monotonic
        spline functions from the 'stats' package. Specifically, the
        code is containted in the files 'R/fastmonoHFC.R',
        'src/fastmonoHFC.c', 'src/modreg.h' and 'src/monoSpl.c'. The R
        Core team and Martin Maechler are the copyright holders of the
        original code. Jan Meis is the copyright holder of everything
        else.
Encoding: UTF-8
VignetteBuilder: knitr
RoxygenNote: 7.2.3
Depends: R (>= 4.0.0), adoptr
Imports: methods, stats, grDevices, cubature, ggplot2, ggpubr, scales,
        latex2exp, forcats, future.apply, progressr, Rdpack
Suggests: covr, knitr, rmarkdown, testthat (>= 3.0.0), microbenchmark
Config/testthat/edition: 3
Collate: 'adestr_package.R' 'twostagedesign_with_cache.R' 'analyze.R'
        'estimators.R' 'densities.R' 'evaluate_estimator.R'
        'fastmonoHFC.R' 'fisher_information.R' 'hcubature.R'
        'helper_functions.R' 'integrate_over_sample_space.R'
        'reference_implementation.R' 'mle_distribution.R'
        'mlmse_score.R' 'n2c2_helpers.R' 'plot.R' 'priors.R' 'print.R'
URL: https://jan-imbi.github.io/adestr/
RdMacros: Rdpack
NeedsCompilation: yes
Packaged: 2024-07-12 13:14:06 UTC; pn425
Author: Jan Meis [aut, cre] (<https://orcid.org/0000-0001-5407-7220>),
  Martin Maechler [cph] (<https://orcid.org/0000-0002-8685-9910>,
    Original author of monoSpl.c (from the 'stats' package).)
Maintainer: Jan Meis <meis@imbi.uni-heidelberg.de>
Repository: CRAN
Date/Publication: 2024-07-12 13:50:09 UTC
Built: R 4.6.0; x86_64-apple-darwin20; 2026-05-01 05:38:55 UTC; unix
Archs: adestr.so.dSYM
