R: R Functions for Chapter 3,4,6,7,9,10,11,12,14,15 of Sample Size Calculation in Clinical Research

# R Functions for Chapter 3,4,6,7,9,10,11,12,14,15 of Sample Size Calculation in Clinical Research

## Documentation for package ‘TrialSize’ version 1.4.1

- DESCRIPTION file

## Help Pages

TrialSize-package | Sample Size calculation in Clinical Research
AB.withDescalation | A + B Escalation Design with Dose De-escalation
AB.withoutDescalation | A + B Escalation Design without Dose De-escalation
ABE | Average Bioequivalence
ANOVA.Repeat.Measure | ANOVA with Repeat Measures
Carry.Over | Test the Carry-over effect
Cochran.Armitage.Trend | Cochran-Armitage's Test for Trend
Cox.Equality | Test for equality in Cox PH model.
Cox.Equivalence | Test for Equivalence in Cox PH model.
Cox.NIS | Test for non-inferiority/superiority in Cox PH model.
CrossOver.ISV.Equality | Test for Equality of Intra-Subject Variabilities in Crossover Design
CrossOver.ISV.Equivalence | Test for Similarity of Intra-Subject Variabilities in Crossover Design
CrossOver.ISV.NIS | Test for Non-Inferiority/Superiority of Intra-Subject Variabilitie in Crossover Design
Dose.Min.Effect | Williams' Test for Minimum effective dose (MED)
Dose.Response.binary | Linear Contrast Test for Binary Dose Response Study
Dose.Response.Linear | Linear Contrast Test for Dose Response Study
Dose.Response.time.to.event | Linear Contrast Test for Time-to-Event Endpoint in dose response study
gof.Pearson | Test Goodness of Fit by Pearson's Test
gof.Pearson.twoway | Test Goodness of Fit by Pearson's Test for two-way table
IBE | Individual Bioequivalence
InterSV.Equality | Test for Equality of Inter-Subject Variabilities
InterSV.NIS | Test for Equality of Inter-Subject Variabilities
ISCV.Equality | Test for Equality of Intra-Subject CVs
ISCV.Equivalence | Test for Equivalence of Intra-Subject CVs
ISCV.NIS | Test for Non-Inferiority/Superiority of Intra-Subject CVs
ISV.Equality | Test for Equality of Intra-Subject Variabilities
ISV.Equivalence | Test for Similarity of Intra-Subject Variabilities
ISV.NIS | Test for Non-Inferiority/Superiority of Intra-Subject Variabilities
McNemar.Test | McNemar Test in 2 by 2 table
MeanWilliamsDesign.Equality | Test for Equality in Multiple-Sample William Design
MeanWilliamsDesign.Equivalence | Test for Equivalence in Multiple-Sample William Design
MeanWilliamsDesign.NIS | Test for Non-Inferiority/Superiority in Multiple-Sample William Design
Multiple.Testing | Multiple Testing procedures
Nonpara.Independ | Test for independence for nonparametric study
Nonpara.One.Sample | One Sample Location problem in Nonparametric
Nonpara.Two.Sample | Two sample location problem for Nonparametric
OneSampleMean.Equality | One Sample Mean Test for Equality
OneSampleMean.Equivalence | One Sample Mean Test for Equivalence
OneSampleMean.NIS | One Sample Mean Test for Non-Inferiority/Superiority
OneSampleProportion.Equality | One sample proportion test for equality
OneSampleProportion.Equivalence | One sample proportion test for equivalence
OneSampleProportion.NIS | One sample proportion test for Non-inferiority/Superiority
OneSide.fixEffect | One-Sided Tests with fixed effect sizes
OneSide.varyEffect | One-Sided Tests with varying effect sizes
OneWayANOVA.pairwise | Pairwise Comparison for Multiple-Sample One-Way ANOVA
OneWayANOVA.PairwiseComparison | One-way ANOVA pairwise comparison
PBE | Population Bioequivalence
Propensity.Score.nostrata | Propensity Score ignoring strata
Propensity.Score.strata | Propensity Score with Stratas
QOL | Quality of life
QT.crossover | Crossover Design in QT/QTc Studies without covariates
QT.parallel | Parallel Group Design in QT/QTc Studies without covariates
QT.PK.crossover | Crossover Design in QT/QTc Studies with PK response as covariate
QT.PK.parallel | Parallel Group Design in QT/QTc Studies with PK response as covariate
RelativeRisk.Equality | Relative Risk in Parallel Design test for Equality
RelativeRisk.Equivalence | Relative Risk in Parallel Design test for Equivalence
RelativeRisk.NIS | Relative Risk in Parallel Design test for Non-inferiority/Superiority
RelativeRiskCrossOver.Equality | Relative Risk in Crossover Design test for Equality
RelativeRiskCrossOver.Equivalence | Relative Risk in Crossover Design test for Equivalence
RelativeRiskCrossOver.NIS | Relative Risk in Crossover Design test for Non-inferiority/Superiority
Sensitivity.Index | Calculate the power for Sensitivity Index
Stuart.Maxwell.Test | Stuart-Maxwell Test
TrialSize | Sample Size calculation in Clinical Research
TwoSampleCrossOver.Equality | Two Sample Crossover Design Test for Equality
TwoSampleCrossOver.Equivalence | Two Sample Crossover Design Test for Equivalence
TwoSampleCrossOver.NIS | Two Sample Crossover Design Test for Non-Inferiority/Superiority
TwoSampleMean.Equality | Two Sample Mean Test for Equality
TwoSampleMean.Equivalence | Two Sample Mean Test for Equivalence
TwoSampleMean.NIS | Two Sample Mean Test for Non-Inferiority/Superiority
TwoSampleProportion.Equality | Two sample proportion test for equality
TwoSampleProportion.Equivalence | Two sample proportion test for equivalence
TwoSampleProportion.NIS | Two sample proportion test for Non-Inferiority/Superiority
TwoSampleSeqCrossOver.Equality | Two sample proportion Crossover design test for equality
TwoSampleSeqCrossOver.Equivalence | Two sample proportion Crossover design test for equivalence
TwoSampleSeqCrossOver.NIS | Two sample proportion Crossover design for Non-inferiority/Superiority
TwoSampleSurvival.Conditional | Test for two sample conditional data in exponential model for survival data
TwoSampleSurvival.Equality | Test for two sample equality in exponential model for survival data
TwoSampleSurvival.Equivalence | Test for two sample equivalence in exponential model for survival data
TwoSampleSurvival.NIS | Test for two sample Non-Inferiority/Superiority in exponential model for survival data
TwoSide.fixEffect | Two-Sided Tests with fixed effect sizes
TwoSide.varyEffect | Two-Sided Tests with varying effect sizes
Vaccine.CEM | Composite Efficacy Measure(CEM) for Vaccine clinical trials.
Vaccine.ELDI | The evaluation of vaccine efficacy with Extremely Low Disease Incidence(ELDI)
Vaccine.RDI | Reduction in Disease Incidence(RDI) for Vaccine clinical trials.
Vitro.BE | In Vitro Bioequivalence
WilliamsDesign.Equality | William Design test for equality
WilliamsDesign.Equivalence | Williams Design test for equivalence
WilliamsDesign.NIS | Williams Design test for Non-inferiority/Superiority