R: Time to Event Outcome in Experimental Designs of Pre-Clinical Studies

# Time to Event Outcome in Experimental Designs of Pre-Clinical Studies

## Documentation for package ‘PDXpower’ version 1.0.5

- DESCRIPTION file
- Package README

## Help Pages

animals1 | Simulated preliminary animals uncensored data
animals2 | Simulated preliminary animals censored data
plotpower | A function to generate a four-panel power curve under specified number of PDX lines and number of individuals per PDX lines per treatment
PowANOVA | A function to obtain a power table with the combination of various number of PDX lines and number of individuals per PDX lines per treatment based on a prior knowledge of median survival
PowANOVADat | A function to obtain a power table with the combination of various number of PDX lines and number of individuals per PDX lines per treatment based on a preliminary dataset
PowFrailty | A function to obtain a power table with the combination of various number of PDX lines and number of individuals per PDX lines per treatment based on a prior knowledge of median survival
PowFrailtyDat | A function to obtain a power table with the combination of various number of PDX lines and number of individuals per PDX lines per treatment based on a preliminary dataset
print.PowerTable | Print PowerTable
SimPDXdata | A function to calculate the power under pre-specified effect size, variance, and correlation using Monte Carlo sampling scheme by fitting ANOVA fixed effects model, ANOVA random effects model, Cox model, and frailty model.