ADPopSel                Simulation-based design of adaptive trials with
                        data-driven population selection
ADPopSelApp             Graphical user interface to design an adaptive
                        trial with data-driven population selection
ADPopSelExample1        Simulation-based design of an adaptive trial
                        with population selection (normally distributed
                        endpoint)
ADPopSelExample2        Simulation-based design of an adaptive trial
                        with population selection (binary endpoint)
ADPopSelExample3        Simulation-based design of an adaptive trial
                        with population selection (time-to-event
                        endpoint)
ADRand                  Simulation-based design of adaptive trials with
                        response-adaptive randomization
ADRandApp               Graphical user interface to design an adaptive
                        trial with data-driven population selection
ADRandExample           Simulation-based design of dose-finding Phase
                        II trials with response-adaptive randomization
                        (normally distributed endpoint)
ADSSMod                 Simulation-based design of adaptive trials with
                        data-driven sample size or event count
                        re-estimation
ADSSModApp              Graphical user interface to design an adaptive
                        trial with data-driven sample size or event
                        count re-estimation
ADSSModExample1         Simulation-based design of an adaptive trial
                        with sample size re-estimation (normally
                        distributed endpoint)
ADSSModExample2         Simulation-based design of an adaptive trial
                        with sample size re-estimation (binary
                        endpoint)
ADSSModExample3         Simulation-based design of an adaptive trial
                        with event count re-estimation (time-to-event
                        endpoint)
ADTreatSel              Simulation-based design of adaptive trials with
                        data-driven treatment selection
ADTreatSelApp           Graphical user interface to design an adaptive
                        trial with data-driven treatment selection
ADTreatSelExample1      Simulation-based design of an adaptive trial
                        with treatment selection (normally distributed
                        endpoint)
ADTreatSelExample2      Simulation-based design of an adaptive trial
                        with treatment selection (binary endpoint)
ADTreatSelExample3      Simulation-based design of an adaptive trial
                        with treatment selection (time-to-event
                        endpoint)
ClustRand               Simulation-based design of cluster-randomized
                        trials
ClustRandApp            Graphical user interface to design a
                        cluster-randomized trial
ClustRandExample1       Simulation-based design of a cluster-randomized
                        trial (normally distributed endpoint)
ClustRandExample2       Simulation-based design of a cluster-randomized
                        trial (binary endpoint)
EventPred               Simulation-based event prediction in trials
                        with an event-driven design
EventPredApp            Graphical user interface for event prediction
                        in trials with an event-driven design
EventPredData           Example data set for EventPred
EventPredExample        Simulation-based event prediction in trials
                        with an event-driven design (time-to- event
                        endpoint)
EventPredPriorDistribution
                        Calculation of the parameters of prior gamma
                        distributions
FutRule                 Simulation-based selection of an optimal
                        futility stopping rule at an interim analysis
FutRuleApp              Graphical user interface for an optimal
                        selection of a futility stopping rule at an
                        interim analysis
FutRuleExample1         Simulation-based selection of an optimal
                        futility stopping rule (normally distributed
                        endpoint)
FutRuleExample2         Simulation-based selection of an optimal
                        futility stopping rule (binary endpoint)
FutRuleExample3         Simulation-based selection of an optimal
                        futility stopping rule (time-to-event endpoint)
GenerateReport          Simulation report
MedianaDesigner-package
                        Efficient Simulation-Based Power and Sample
                        Size Calculations for a Broad Class of
                        Late-Stage Clinical Trials
MultAdj                 Simulation-based design of traditional trials
                        with multiple objectives
MultAdjApp              Graphical user interface for power calculations
                        in traditional trials with multiple objectives
MultAdjExample1         Simulation-based power calculations in Phase
                        III trials with multiple dose-placebo
                        comparisons
MultAdjExample2         Simulation-based power calculations in Phase
                        III trials with multiple endpoints
MultAdjExample3         Simulation-based power calculations in Phase
                        III trials with multiple endpoints and multiple
                        dose-placebo comparisons
