R: Designing Multi-Arm Multi-Stage Studies

# Designing Multi-Arm Multi-Stage Studies

## Documentation for package ‘MAMS’ version 3.0.3

- DESCRIPTION file
- Package NEWS

## Help Pages

.onAttach | .onAttach
a | Function to design multi-arm multi-stage studies with normal endpoints
and | Function to design multi-arm multi-stage studies with normal endpoints
boundaries | Function to design multi-arm multi-stage studies with normal endpoints
boundary | Function to design multi-arm multi-stage studies with normal endpoints
determines | Function to design multi-arm multi-stage studies with normal endpoints
finds | Function to design multi-arm multi-stage studies with normal endpoints
for | Function to design multi-arm multi-stage studies with normal endpoints
function | Function to design multi-arm multi-stage studies with normal endpoints
given | Function to design multi-arm multi-stage studies with normal endpoints
MAMS | Function to design multi-arm multi-stage studies with normal endpoints
mams | Function to design multi-arm multi-stage studies with normal endpoints
mams.sim | Simulating multi-arm multi-stage designs
MAMSNews | Shows changes and news
multi-arm | Function to design multi-arm multi-stage studies with normal endpoints
multi-stage | Function to design multi-arm multi-stage studies with normal endpoints
new.bounds | Function to update boundaries based on observed sample sizes
number | Function to design multi-arm multi-stage studies with normal endpoints
of | Function to design multi-arm multi-stage studies with normal endpoints
ordinal.mams | Function to design multi-arm multi-stage studies with ordinal or binary endpoints
plot.MAMS | Plot method for MAMS objects
plot.MAMS.stepdown | Plot method for MAMS.stepdown objects
print.MAMS | Generic print function for class MAMS.
print.MAMS.stepdown | Generic print function for class MAMS.stepdown.
required | Function to design multi-arm multi-stage studies with normal endpoints
shape | Function to design multi-arm multi-stage studies with normal endpoints
stepdown.mams | Function to find stopping boundaries for a 2- or 3-stage (step-down) multiple-comparisons-with-control test.
stepdown.update | Update the stopping boundaries of multi-arm multi-stage study at an interim analysis, allowing for unplanned treatment selection and/or sample-size reassessment.
study | Function to design multi-arm multi-stage studies with normal endpoints
subjects. | Function to design multi-arm multi-stage studies with normal endpoints
summary.MAMS | Generic summary function for class MAMS.
summary.MAMS.stepdown | Generic summary function for class MAMS.stepdown.
The | Function to design multi-arm multi-stage studies with normal endpoints
the | Function to design multi-arm multi-stage studies with normal endpoints
tite.mams | Function to design multi-arm multi-stage studies with time-to-event endpoints