Package: DamageDetective
Type: Package
Title: Detecting Damaged Cells in Single-Cell RNA Sequencing Data
Version: 1.0.0
Authors@R: 
    person("Alicen", "Henning", email = "alicen.jhb@gmail.com",
    role = c("aut", "cre", "cph"),
    comment = c(ORCID = "0009-0004-0535-1624"))
Description: Detects and filters damaged cells in single-cell RNA sequencing
    (scRNA-seq) data using a novel approach inspired by 'DoubletFinder'. Damage
    is detected by measuring the extent to which cells deviate from
    artificially damaged profiles of themselves, simulated through the
    probabilistic escape of cytoplasmic RNA. As output, a damage score
    ranging from 0 to 1 is given for each cell providing an intuitive scale for 
    filtering that is standardised across cell types, samples, and experiments.
License: AGPL (>= 3)
Encoding: UTF-8
Language: en-US
LazyData: false
RoxygenNote: 7.3.2
Depends: R (>= 4.4.0)
Imports: cowplot, dplyr, ggplot2, ggpubr, Matrix, patchwork, scales,
        RcppHNSW, rlang, tidyr, withr
Suggests: Seurat, knitr, rmarkdown, spelling
VignetteBuilder: knitr
URL: https://alicenjoyhenning.github.io/DamageDetective/,
        https://github.com/alicenjoyhenning/DamageDetective
BugReports: https://github.com/alicenjoyhenning/DamageDetective/issues
NeedsCompilation: no
Packaged: 2025-04-03 10:53:38 UTC; alicen
Author: Alicen Henning [aut, cre, cph]
    (<https://orcid.org/0009-0004-0535-1624>)
Maintainer: Alicen Henning <alicen.jhb@gmail.com>
Repository: CRAN
Date/Publication: 2025-04-03 16:20:02 UTC
Built: R 4.6.0; ; 2026-05-01 03:31:53 UTC; unix
