Package: AEenrich
Version: 1.1.1
Title: Adverse Event Enrichment Tests
Type: Package
Description: We extend existing gene enrichment tests to perform adverse
    event enrichment analysis. Unlike the continuous gene expression data,
    adverse event data are counts. Therefore, adverse event data has many zeros
    and ties. We propose two enrichment tests. One is a modified Fisher's exact
    test based on pre-selected significant adverse events, while the other is
    based on a modified Kolmogorov-Smirnov statistic. We add Covariate
    adjustment to improve the analysis."Adverse event enrichment tests using
    VAERS" Shuoran Li, Lili Zhao (2020) <doi:10.48550/arXiv.2007.02266>.
Authors@R: c(
    person(given = "Shuoran", family = "Li", role = c("aut"), email = "shuoranl@umich.edu"),
    person(given = "Hongfan", family = "Chen", role = c("aut"), email = "chenhf@umich.edu"),
    person(given = "Lili", family = "Zhao", role = c("aut"), email = "zhaolili@med.umich.edu"),
    person(given = "Michael", family = "Kleinsasser", role = c("aut", "cre"), email = "mkleinsa@umich.edu"))
License: GPL-2
Encoding: UTF-8
LazyData: true
Biarch: true
Depends: R (>= 3.5.0)
Imports: dplyr, magrittr, qvalue, doParallel, tidyr, modelr, foreach,
        rlang, utils
biocViews:
URL: https://github.com/umich-biostatistics/AEenrich
BugReports: https://github.com/umich-biostatistics/AEenrich/issues
RoxygenNote: 7.3.3
Suggests: testthat
NeedsCompilation: no
Packaged: 2026-01-22 14:17:55 UTC; mk
Author: Shuoran Li [aut],
  Hongfan Chen [aut],
  Lili Zhao [aut],
  Michael Kleinsasser [aut, cre]
Maintainer: Michael Kleinsasser <mkleinsa@umich.edu>
Repository: CRAN
Date/Publication: 2026-01-22 14:30:02 UTC
Built: R 4.6.0; ; 2026-04-30 18:33:02 UTC; unix
