R: Centered Isotonic Regression and Dose-Response Utilities

# Centered Isotonic Regression and Dose-Response Utilities

## Documentation for package ‘cir’ version 2.5.1

- DESCRIPTION file.
- User guides, package vignettes and other documentation.

## Help Pages

cir-package | Isotonic Regression, Centered Isotonic Regression, and Dose-Response Utilities
agcouCI | Standard unordered-Binomial confidence interval utilities.
cir | Isotonic Regression, Centered Isotonic Regression, and Dose-Response Utilities
cirPAVA | Centered-isotonic-regression (CIR) point estimation
deltaInverse | Backend utility to calculate inverse (dose-finding) intervals, using local inversion and the Delta method
doseFind | Inverse (dose-finding) point estimate (e.g., estimating a percentile)
doseResponse | Constructor functions and class-checking functions for DRtrace and doseResponse classes
DRshrink | Shrinkage fix to mitigate bias in observed rates, under adaptive dose-finding designs
DRtrace | Constructor functions and class-checking functions for DRtrace and doseResponse classes
is.doseResponse | Constructor functions and class-checking functions for DRtrace and doseResponse classes
is.DRtrace | Constructor functions and class-checking functions for DRtrace and doseResponse classes
isotInterval | Backend utility to calculate analytical CIR/IR interval estimates, given the point estimates
jeffCI | Standard unordered-Binomial confidence interval utilities.
morrisCI | Analytical ordered-binary-Y confidence intervals, using the Morris (1988) algorithm
oldPAVA | "Old School" isotonic-regression point estimates, with flexible dose-response input
plot.doseResponse | Plotting Methods for DRtrace, doseResponse Objects
plot.DRtrace | Plotting Methods for DRtrace, doseResponse Objects
quickInverse | Convenient point and Interval Inverse Estimation ("Dose-Finding"), using CIR or IR
quickIsotone | Convenient Forward point and interval estimation via CIR or IR
slope | Piecewise-linear local slopes given a (non-strictly) monotone x-y sequence
wilsonCI | Standard unordered-Binomial confidence interval utilities.