Package: power.nb
Title: Power and Sample Size Calculation for Differential Abundance
        Microbiome Studies
Version: 0.1.0
Authors@R: 
   c(person("Michael", "Agronah", 
           email =  "michaelagronah@gmail.com", role = c("aut","cre"),
           comment = c(ORCID = "0009-0007-2655-4094")),
   person("Ben","Bolker", role="aut", 
     email =  "bolker@mcmaster.ca",
   comment=c(ORCID="0000-0002-2127-0443"))
   )
Description: Provides functions for estimating statistical power and required sample sizes 
    in differential abundance microbiome studies using negative binomial models. 
    The methods are based on Agronah and Bolker (2025) <doi:10.1371/journal.pone.0318820>.
    The package includes tools for simulation-based power analysis and sample size 
    estimation using generalized additive models (GAMs), and visualization utilities for exploring 
    the relationship between power, effect size, abundance, and sample size.
License: MIT + file LICENSE
URL: https://michaelagronah.com/power.nb/
BugReports: https://github.com/magronah/power.nb/issues
Encoding: UTF-8
VignetteBuilder: knitr
Depends: R (>= 4.1.0)
Imports: DESeq2, fitdistrplus, rlang, minpack.lm,foreach,tibble, purrr,
        mixtools, scam, ggplot2, ggrastr, metR, DEoptim, latex2exp,
        parallel,stats,doParallel
Suggests: rmarkdown, knitr, kableExtra, tidyverse, patchwork, dplyr,
        rlist
biocViews:
RoxygenNote: 7.3.3
NeedsCompilation: no
Packaged: 2026-06-07 01:18:19 UTC; michaelagronah
Author: Michael Agronah [aut, cre] (ORCID:
    <https://orcid.org/0009-0007-2655-4094>),
  Ben Bolker [aut] (ORCID: <https://orcid.org/0000-0002-2127-0443>)
Maintainer: Michael Agronah <michaelagronah@gmail.com>
Repository: CRAN
Date/Publication: 2026-06-15 11:50:07 UTC
Built: R 4.5.2; ; 2026-06-15 13:10:36 UTC; unix
