R: Centered Isotonic Regression and Dose-Response Utilities

# Centered Isotonic Regression and Dose-Response Utilities

## Documentation for package ‘cir’ version 2.3.1

- DESCRIPTION file.
- User guides, package vignettes and other documentation.

## Help Pages

agcouCI | Standard unordered-Binomial confidence interval utilities.
cir | Isotonic Regression, Centered Isotonic Regression, and Dose-Response Utilities
cirPAVA | Returns centered-isotonic-regression estimate
deltaInverse | Calculate inverse (dose-finding) intervals, using local inversion and the Delta method
doseFind | Inverse (dose-finding) estimate of a target x value (e.g., a percentile)
doseResponse | Constructor functions and class-checking functions for DRtrace and doseResponse classes
DRshrink | Shrinkage fix to bias in observed rates under adaptive dose-finding design
DRtrace | Constructor functions and class-checking functions for DRtrace and doseResponse classes
is.doseResponse | Constructor functions and class-checking functions for DRtrace and doseResponse classes
is.DRtrace | Constructor functions and class-checking functions for DRtrace and doseResponse classes
isotInterval | Returns analytical interval estimates, given isotonic-regression (centered or not) point estimates
iterCIR | Centered-isotonic-regression (CIR): iterative version for better bias correction
jeffCI | Standard unordered-Binomial confidence interval utilities.
morrisCI | Analytical confidence intervals using the Morris (1988) algorithm
oldPAVA | Returns standard isotonic-regression estimate, with flexible dose-response input
plot.doseResponse | Plotting Methods for DRtrace, doseResponse Objects
plot.DRtrace | Plotting Methods for DRtrace, doseResponse Objects
quickInverse | Point and Interval Inverse Estimation ("Dose-Finding"), using CIR and IR
quickIsotone | One-Stop-shop Forward point and interval estimation via CIR or IR
slope | Piecewise-linear local slopes given a (non-strictly) monotone x-y sequence
wilsonCI | Standard unordered-Binomial confidence interval utilities.