R: CFO-Type Designs in Phase I Clinical Trials

# CFO-Type Designs in Phase I Clinical Trials

## Documentation for package ‘CFO’ version 1.1.1

- DESCRIPTION file.

## Help Pages

aCFO.next | Determination of the dose level for next cohort in the accumulative calibration-free odds (aCFO) design
CFO.next | Determination of the dose level for next cohort in the calibration-free odds (CFO) design
CFO.oc | Generate operating characteristics of sigle-drug trials in multiple simulations
CFO.selectmtd | Select the maximum tolerated dose (MTD) for the real single-drug trial
CFO.simu | Conduct one simulation using the Calibration-free odds (CFO) or accumulative CFO (aCFO) design.
CFO2d.next | Determinate the dose level for the next cohort in the two-dimensional calibration-free odds (2dCFO) design.
CFO2d.oc | Generate operating characteristics of drug-combination trials in multiple simulations
CFO2d.selectmtd | Select the maximum tolerated dose (MTD) for the real drug combination trial
CFO2d.simu | Conduct one simulation using the two-dimensional calibration-free odds (2dCFO) design.
lateonset.next | Determination of the dose level for next cohort in the calibration-free odds type (CFO-type) design with late-onset toxicity
lateonset.simu | Conduct one simulation using the calibration-free odds type (CFO-type) design with late-onset toxicity.
plot.cfo | Plot the results by other functions
print.cfo | Generate descriptive summary for objects returned by other functions
summary.cfo | Generate descriptive summary for objects returned by other functions